Body

CHICAGO --- A drug used to treat cancer may also be effective in diseases that cause scarring of the internal organs or skin, such as pulmonary fibrosis or scleroderma.

The drug, with the generic name bortezomib, stopped the production of fibrotic proteins in human cells and the development of fibrous scarring in a mouse model of fibrotic disease, according to a new Northwestern Medicine study published in the journal Thorax.

AMES, Iowa - For decades, scientists have believed that a relationship exists between how much biomass plant species produce and how many species can coexist.

This idea comes from a 1970s study that showed as plant biomass produced – called plant productivity - in a system increased, so did the number of plant species – referred to as plant richness - to a point. After that point, the number of plant species is thought to decline.

SEATTLE, WA -- Opioids -- a class of medicines commonly given for pain -- were associated with a higher risk of pneumonia in a study of 3,061 adults, aged 65 to 94, e-published in advance of publication in the Journal of the American Geriatrics Society. The study from researchers at Group Health Research Institute and the University of Washington (UW) also found that benzodiazepines, which are drugs generally given for insomnia and anxiety, did not affect pneumonia risk.

African ranchers often prefer to keep wild grazers like zebras off the grass that fattens their cattle.

But a new study by Kenyan and University of California at Davis researchers shows that grazing by wild animals doesn't always harm, and may sometimes benefit, cattle.

The results are published in this week's issue of the journal Science.

For immediate release -- Sept. 22, 2011 (Toronto) -- A new research study conducted by an international team of experts recommends a public health approach to cannabis - including evidence-based guidelines for lower-risk use - to reduce the health harms that result from the use of cannabis. Led by CAMH scientist and CIHR/PHAC* Chair in Applied Public Health (Simon Fraser University, Vancouver) Dr. Benedikt Fischer, the study is being published in the September/October 2011 issue of the Canadian Journal of Public Health (CJPH).

Females in inbred populations become more promiscuous in order to screen out sperm from genetically incompatible males, according to new study by the University of East Anglia (UEA).

Published tomorrow in the journal Science, the findings help answer the puzzling evolutionary question of why females in most species mate with multiple males – even though a single male can provide full fertility and promiscuity can carry fatal risks for the female.

RIVERSIDE, Calif. – An international research team led by biologists at the University of California, Riverside and Texas A&M University has released for the first time a large and robust DNA matrix that has representation for all mammalian families. The matrix – the culmination of about five years of painstaking research – has representatives for 99 percent of mammalian families, and covers not only the earliest history of mammalian diversification but also all the deepest divergences among living mammals.

In an exciting development, an international team of researchers have, for the first time, pieced together the human genome from an Aboriginal Australian. The results, now to be published in the international journal Science, re-interpret the prehistory of our species.

Children with severe therapy-resistant asthma (STRA) may have poorer lung function and worse symptoms compared to children with moderate asthma, due to lower levels of vitamin D in their blood, according to researchers in London. Lower levels of vitamin D may cause structural changes in the airway muscles of children with STRA, making breathing more difficult. The study provides important new evidence for possible treatments for the condition.

ROCHESTER, Minn. -- Researchers at Mayo Clinic are hacking the genetic code that controls the human response to disease vaccination, and they are using this new cipher to answer many of the deep-seated questions that plague vaccinology, including why patients respond so differently to identical vaccines and how to minimize the side effects to vaccination.

Bethesda, Md. (Sept. 22, 2011) – The kidney performs several vital functions. It filters blood, removes waste products from the body, balances the body's fluids, and releases hormones that regulate blood pressure. A number of diseases and conditions can damage the kidney's filtration apparatus, such as diabetes and immune disorders. This damage leads to a condition called nephrotic syndrome, which is characterized by protein in the urine, high cholesterol and triglycerides, and swelling (edema).

A new study published in the November 2011 issue of Stroke reveals some promising data on the positive effects of soy protein reducing the progression of clogged arteries in women who were within five years of menopause. This study was the largest and longest randomized controlled human study conducted to-date that directly investigated the efficacy of isolated soy protein consumption on the progression of atherosclerosis (lipid deposition in the artery walls).

Berkeley — Researchers at the University of California, Berkeley, have turned back the clock on mature muscle tissue, coaxing it back to an earlier stem cell stage to form new muscle. Moreover, they showed in mice that the newly reprogrammed muscle stem cells could be used to help repair damaged tissue.

An international team of researchers studying DNA patterns from modern and archaic humans has uncovered new clues about the movement and intermixing of populations more than 40,000 years ago in Asia.

Bethesda, Md. (Sept. 22, 2011) -- Maintaining fluid balance in the body is essential to survival, from the tiniest protozoa to the mightiest of mammals. By researching recent genomic data, Swiss researchers have found genetic evidence that links this intricate process to a turning point in evolution.