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Current guidelines that help clinicians decide whether a woman has had a miscarriage are inadequate and not reliable, and following them may lead to the inadvertent termination of wanted pregnancies. This is the conclusion of a series of papers published in the international journal Ultrasound in Obstetrics and Gynecology. "This research shows that the current guidance on how to use ultrasound scans to detect a miscarriage may lead to a wrong diagnosis in some cases.

The current ultrasound test to diagnose miscarriage in early pregnancy is based on limited evidence, raising questions about its reliability, according to a new paper* published by researchers at Queen Mary, University of London.

The researchers say that there is an urgent need to conduct a large-scale study for us to be confident that diagnosis of miscarriage is correct in every case using the ultrasound measurements.

Women with polycystic ovary syndrome are more likely to have problems with pregnancy regardless of whether they are undergoing fertility treatment, claims new research published on bmj.com today.

The Swedish researchers call for better monitoring of women with polycystic ovary syndrome during pregnancy and childbirth because they are more prone to premature birth, diabetes and pre-eclampsia – outcomes which are not explained by assisted reproductive technology, as previously thought.

Human genes are preferentially encoded by codons that are less likely to be mistranscribed (or "misread") into a STOP codon. This finding by Brian Cusack and colleagues from the Max Planck Institute for Molecular Genetics in Berlin and the CNRS in Lyon and Paris is published in the open-access journal PLoS Genetics on October 13th, 2011.

PHILADELPHIA -- Nose feel congested and stuffed up? Scientists from the Monell Center report that the annoying feeling of nasal obstruction is related to the temperature and humidity of inhaled air. The findings suggest that sensory feedback from nasal airflow contributes to the sensation of congestion. This knowledge may help researchers design and test more effective treatments for this familiar symptom of nasal sinus disease.

Researchers have discovered a toxin – SElX – released by Methicillin-resistant Staphylococcus aureus (MRSA) which leads the body's immune system to go into overdrive and damage healthy cells. SElX is made by 95 per cent of Staphylococcus aureus bacteria, making it a potential drug target to fight the hospital superbug. Their findings appear October 13th in the Open Access journal PLoS Pathogens.

An international team of scientists led by Monash University researchers has uncovered how a common hospital bacterium becomes a deadly superbug that kills increasing numbers of hospital patients worldwide and accounts for an estimated $3.2 billion each year in health care costs in the US alone. Their findings appear October 13th in the Open Access journal PLoS Pathogens.

Targeting a toxin released by virtually all strains of MRSA could help scientists develop new drugs that can fight the superbug, research suggests.

A study led by the University of Edinburgh has discovered the toxin -- SElX -- which leads the body's immune system to go into overdrive and damage healthy cells.

The toxin SElX is made by 95 per cent of Staphylococcus aureus bacteria, including MRSA strains linked with hospital-acquired infections.

Researchers funded by the Biotechnology and Biological Sciences Research Council (BBSRC), among others, have taken the first step in developing a new type of vaccine to protect chickens against coccidiosis, the most important parasite of poultry globally.

A vaccine of this type -- based on proteins from the coccidiosis bug rather than being derived from a live parasite -- could be produced on a larger scale than is currently possible so could be used to provide much more widespread protection to chicken flocks.

DURHAM, N.C. - Statins can be effective at lowering cholesterol, but they have a perplexing tendency to work for some people and not others. Gut bacteria may be the reason.

A research team led by a Duke University scientist has identified three bile acids produced by gut bacteria that were evident in people who responded well to a common cholesterol-lowering drug called simvastatin. The finding, published Oct. 13, 2011, in PLoS One, demonstrates how gut bacteria can cause inherent differences in the way people digest, metabolize and benefit from substances such as drugs.

First it was chess. Then it was Jeopardy.

Now computers are at it again, but this time they are trying to automate the scientific process itself.

Why don't our arms grow from the middle of our bodies? The question isn't as trivial as it appears. Vertebrae, limbs, ribs, tailbone ... in only two days, all these elements take their place in the embryo, in the right spot and with the precision of a Swiss watch. Intrigued by the extraordinary reliability of this mechanism, biologists have long wondered how it works. Now, researchers at EPFL (Ecole Polytechnique Fédérale de Lausanne) and the University of Geneva (Unige) have solved the mystery. Their discovery will be published October 13, 2011 in the journal Science.

Researchers from the University of Notre Dame have announced a breakthrough approach to allergy treatment that inhibits food allergies, drug allergies, and asthmatic reactions without suppressing a sufferer's entire immunological system.

The therapy centers on a special molecule the researchers designed, a heterobivalent ligand (HBL), which when introduced into a person's bloodstream can, in essence, out-compete allergens like egg or peanut proteins in their race to attach to mast cells, a type of white blood cell that is the source of type-I hypersensitivity (that is, allergy).

Los Angeles, CA (October 13, 2011) Workplace violence continues to be a topic of great importance to many companies, as tales of extreme cases hit the media. Today's human resources departments spend a great deal of time preparing for these cases. However, a new study in the journal Advances in Developing Human Resources (ADHR) questions whether time might be better invested in further investigation.

An ochre-rich mixture, possibly used for decoration, painting and skin protection 100,000 years ago, and stored in two abalone shells, was discovered at Blombos Cave in Cape Town, South Africa.

"Ochre may have been applied with symbolic intent as decoration on bodies and clothing during the Middle Stone Age," says Professor Christopher Henshilwood from the Institute for Human Evolution at the University of the Witwatersrand, Johannesburg, who together with his international team discovered a processing workshop in 2008 where a liquefied ochre-rich mixture was produced.