Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have identified a cell cycle-regulated mechanism behind the transformation of normal cells into cancerous cells. The study shows the significant role that protein networks can play in a cell leading to the development of cancer.
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Among known risk factors for hepatocellular cancer, smoking, obesity, and heavy alcohol consumption, along with chronic hepatitis B and C infection, contribute to a large share of the disease burden in Europe, according to a cohort study published online October 21 in the Journal of the National Cancer Institute.
ROCHESTER, Minn. -- Recent studies have suggested that C-11 choline positron emission tomography/computerized tomography (PET/CT) scans can be utilized as a staging and potentially therapeutic tool in prostate cancer. The results of three studies, released today during a meeting of the North Central Section of the American Urological Association (http://www.ncsaua.org/default.aspx), validate findings in Europe and expand the potential use of C-11 choline PET scans.
The National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, has stopped one arm of a three arm multi-center, clinical trial studying treatments for the lung-scarring disease idiopathic pulmonary fibrosis (IPF) for safety concerns. The trial found that people with IPF receiving a currently used triple-drug therapy consisting of prednisone, azathioprine, and N-acetylcysteine (NAC) had worse outcomes than those who received placebos, or inactive substances.
Athletes know they should just do their thing on the 18th hole, or during the penalty shootout, or when they're taking a 3-point shot in the last moments of the game. But when that shot could mean winning or losing, it's easy to choke. A new article published in Current Directions in Psychological Science, a journal of the Association for Psychological Science, looks at why paying too much attention to what you're doing can ruin performance.
WORCESTER, Mass. — A team of researchers at the University of Massachusetts Medical School, Harvard Medical School, Stanford University and the Prince Felipe Research Centre in Spain have deciphered the complete three-dimensional structure of the bacterium Caulobacter crescentus's chromosome. Analysis of the resulting structure —published this week in Molecular Cell — has revealed new insights into the function of genetic sequences responsible for the shape and structure of this genome.
Despite the proliferation of social networks, many Americans feel alone and isolated. According to a new study in the Journal of Consumer Research, lonely individuals behave differently in the marketplace than people with strong social networks.
"Picture yourself hiking through the woods or walking across a lawn," says Elizabeth Haswell, PhD, assistant professor of biology in Arts & Sciences at Washington University in St. Louis. "Now ask yourself: Do the bushes know that someone is brushing past them? Does the grass know that it is being crushed underfoot? Of course, plants don't think thoughts, but they do respond to being touched in a number of ways."
Consumers who tell little white lies to avoid confrontation might find themselves rewarding the people who inconvenienced them, according to a new study in the Journal of Consumer Research.
"Most consumers have told an inquiring server that their cold meal is fine, a hairdresser that they like their unexpected 'new look,' or a friend that his/her too-snug jeans look great," write authors Jennifer J. Argo (University of Alberta) and Baba Shiv (Stanford University). But according to the researchers, white lies have negative repercussions for the people who tell them.
Consumers who feel powerless will choose larger size food portions in an attempt to gain status, according to a new study in the Journal of Consumer Research. But there is hope for convincing them that a Big Gulp won't translate to higher ranking.
Consumers need a little help when it comes to imagining using products, according to a new study in the Journal of Consumer Research. Sometimes that means orienting an advertisement toward a dominant hand or helping them picture using the product (like putting a spoon in a soup advertisement).
"Across four studies we show that by simply orienting a product toward one's dominant (vs. non-dominant hand) in a visual advertisement leads to increases in imagined product use," write authors Ryan S. Elder (Brigham Young University) and Aradhna Krishna (University of Michigan).
Consumers are more likely to choose products when marketers withhold some favorable information until late in the choice process, according to the Journal of Consumer Research. But marketers need to walk a fine line to disclose information at just the right time.
People whose basic needs are met get more life satisfaction when they are more connected to others and when they experience greater autonomy, according to a new study in the Journal of Consumer Research. But those who live in dire conditions have little hope of achieving such satisfaction.
In a report to be published soon in EPJE¹, researchers from the National University of the South in Bahía Blanca, Argentina studied the condition for model cavity and tunnel structures resembling the binding sites of proteins to stay dry without losing their ability to react, a prerequisite for proteins to establish stable interactions with other proteins in water.
E.P. Schulz and colleagues used models of nanometric-scale hydrophobic cavities and tunnels to understand the influence of geometry on the ability of those structures to stay dry in solution.
Reconstructive surgical approaches can help delay endoprosthetic joint replacement in patients with osteoarthritis. Henning Madry and coauthors introduce such procedures in the current issue of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2011; 108[40]: 669-77).