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Army scientists working as part of an international consortium have developed and tested an antibody-based therapy to treat Crimean-Congo hemorrhagic fever virus (CCHFV), which is carried by ticks and kills up to 60 percent of those infected. Their results are published online today in the journal Cell.

A new study carried out in pig cells suggests previous infection with swine influenza virus (SIV) can protect against the development of porcine respiratory coronavirus (PRCoV) if there is a zero- or three-day interval between infections.

The findings, published in the peer-reviewed journal Virulence, may also be relevant to influenza and coronavirus infection in humans.

New research has shown that if people achieve and maintain substantial weight loss to manage their type 2 diabetes, many can also effectively control their high blood pressure and stop or cut down on their anti-hypertensive medication.

A weight management programme, developed by researchers at the Universities of Glasgow and Newcastle for the Diabetes UK-funded DIabetes REmission Clinical Trial (DIRECT), has proved effective at lowering blood pressure and reducing the need for anti-hypertensive medications, as well as bringing remission of type 2 diabetes.

An emotion regulation strategy known as cognitive reappraisal helped reduce the typically heightened and habitual attention to drug-related cues and contexts in cocaine-addicted individuals, a study by Mount Sinai researchers has found. In a paper published in PNAS, the team suggested that this form of habit disruption, mediated by the prefrontal cortex (PFC) of the brain, could play an important role in reducing the compulsive drug-seeking behavior and relapse that are the hallmarks, and long-standing challenges, of addiction.

Sophia Antipolis - 1 June 2021: A study in 5.8 million children has found a higher incidence of stroke four decades later in those whose mother had high blood pressure or pre-eclampsia while pregnant. The research is presented at ESC Heart & Stroke 2021, an online scientific conference of the European Society of Cardiology (ESC).1

What The Study Did: Rates of antispike antibody response to a messenger RNA SARS-CoV-2 vaccine in Israeli patients with cancer who are undergoing systemic treatment compared with healthy controls were evaluated in this study.

Authors: Salomon M. Stemmer, M.D., of the Rabin Medical Center in Petah Tikva, Israel, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ 

(doi:10.1001/jamaoncol.2021.2155)

What The Study Did: This study evaluates whether there are differences in SARS-CoV-2 seroprevalence and antibody levels in patients with cancer compared with health care workers in Japan.

Authors: Tatsuya Yoshida, M.D., Ph.D., of the National Cancer Center Hospital in Tokyo, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ 

(doi:10.1001/jamaoncol.2021.2159)

What The Study Did: Researchers examined social connectedness among Medicare beneficiaries during the COVID-19 pandemic.

Authors: Wesley John Talcott, M.D., M.B.A., the Yale School of Medicine in New Haven, Connecticut, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamainternmed.2021.2348)

Singapore University of Technology and Design (SUTD) researchers have uncovered how the environment can impact highly sensitive quantum behaviours like localisation. Their findings, published in Chaos, could lead to future innovations in the design of superconducting materials and quantum devices, including super precise sensors.

In the Philippines, in the early months of the COVID-19 pandemic, there occurred a supply shortage of hydroxychloroquine and methotrexate. Limited access to medication and the life changes caused from the COVID-19 pandemic may prompt patients with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) to experience disease flares.

The Montreal Heart Institute (MHI) announces that the COLCORONA study results are published today in The Lancet Respiratory Medicine.

Scientists from the Wellcome Sanger Institute and the University of Cambridge found that in children with neuroblastoma - a cancer of immature nerve cells - treatment with platinum chemotherapy caused changes to the genome that could then cause leukaemia in some children later on.

The findings, published 27th May 2021 in Blood could lead to an ability to identify which children are more likely to develop the secondary cancer. This in turn could lead to changes in their treatment plan to either avoid these risks or take measures to prepare.

Eating habits amongst the young changed during the lockdown imposed due to COVID-19 and worsened in the case of those belonging to socioeconomically disadvantaged groups. These are the chief findings of an open access study published in specialist journal Nutrients, headed by researchers Alícia Aguilar Martínez, of the Universitat Oberta de Catalunya, and Marina Bosque Prous, of the UOC and UManresa, as part of the DESKcohort project of the interuniversity Epidemiology and Public Health research group GRESP.

Analysis using a national medical database revealed that the cumulative incidence of autism spectrum disorders (ASD) in children born in 2009-2014 was 2.75% by the age of five. A research group led by Associate Professor Daimei Sasayama and Professor Hideo Honda of the Department of Child and Adolescent Development Psychiatry, Shinshu University School of Medicine, used a national medical database to analyze autism spectrum disorders in Japan. It was reported that the cumulative incidence showed an increasing trend for each year of birth, and that there were regional differences.