In the United States, lung cancer is responsible for 27% of all cancer deaths, claiming an estimated 160,000 lives per year [1]. While smoking is linked to as many as 90% of lung cancer cases, this new study suggests that atmospheric oxygen may play a role in lung carcinogenesis.
Body
Researchers at the Montreal Heart Institute announced today results showing that patients with cardiovascular disease and the appropriate genetic background benefit greatly from the new medication dalcetrapib, with a reduction of 39% in combined clinical outcomes including heart attacks, strokes, unstable angina, coronary revascularizations and cardiovascular deaths. These patients also benefit from a reduction in the amount of atherosclerosis (thickened walls) in their vessels. The detailed results are published in the prestigious Journal Circulation Cardiovascular Genetics.
Researchers have identified hyaluronon (HA) as a critical substance made by the body that protects against premature births caused by infection. Pre-term birth from infection is the leading cause of infant mortality in many countries according to the World Health Organization.
The findings of the study, recently published in the Journal of Clinical Investigation, are the first to identify the specific role that HA plays in the reproductive tract.
Epigenetic signals help determine which genes are activated at which time in a given cell. A novel analytical method enables systematic characterization of the relevant epigenetic tags, and reveals that the system adapts to the loss of single epigenetic writer and eraser enzymes.
A new paper in Applied Physiology, Nutrition, and Metabolism investigated the nutritional benefits of novel beverages (vitamin waters, energy drinks, and novel juices) sold in Canadian supermarkets by assessing their micronutrient compositions.
"May contain nuts" - this amount of allergen will cause a reaction in only 10 percent with allergies
"May contain nuts" is a common warning label because that is a requirement. Some people have a severe reaction to some allergens. But most people don't. Like "I have the flu", severe allergy is subjective and often misused yet there are even labels like 'produced in a factory which also handles peanuts', which is valuable for people who can go into anaphylactic shock but confusing for everyone else.
For most people, how much is too much?
Sepsis is a leading cause of death for patients in intensive care units. The excessive systemic inflammation in individuals with sepsis damages organs and can lead to death.
Air Force reservists based in the U.S. who worked after the Vietnam War in C-123 aircraft that sprayed Agent Orange during the war could have experienced adverse health effects from exposure to the herbicide, says a new report from the Institute of Medicine. The reservists who served in the contaminated C-123s experienced some degree of exposure to the toxic chemical component of Agent Orange known as TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin), and it is plausible, in some cases, that the reservists exceeded TCDD exposure guidelines for workers in enclosed settings.
For patients with spinal stenosis, long-term outcomes are comparable with surgery or conservative treatment, according to a new study.
A large international study has shown conclusively that statin treatment reduces the risk of cardiovascular disease in women. Whether statin therapy is as effective in women as in men is debated, especially for primary prevention. This study published today in The Lancet, compared the effects of statin therapy between men and women.
With hypertension (HTN) affecting nearly 80 million people in the United States and cardiovascular disease (CVD) the leading cause of death, any intervention that can lower blood pressure has the potential to save lives. In a study in the current issue of the Journal of the Academy of Nutrition and Dietetics, Florida State University researchers found that daily consumption of blueberries for eight weeks resulted in significant reductions of both systolic and diastolic blood pressure.
A study of more than 2,000 patients by researchers at Mayo Clinics has dispelled the myth that cancer biopsies cause cancer to spread. In the Jan. 9 online issue of Gut, they show that patients who received a biopsy had a better outcome and longer survival than patients who did not have a biopsy.
A new study identifies the BCL11A gene is especially active in aggressive subtypes of breast cancer. The research suggests that an overactive BCL11A gene drives triple-negative breast cancer development and progression. The research, which was done in human cells and in mice, provides new routes to explore targeted treatments for this aggressive tumor type.
Researchers at King's College London have identified a new mechanism by which skin damage triggers the formation of tumours, which could have important therapeutic implications for patients suffering with chronic ulcers or skin blistering diseases.
The study, published today in Nature Communications, highlights an innate sensing of bacteria by immune cells in the formation of skin tumours. This molecular process could tip the balance between normal wound repair and tumour formation in some patients, according to researchers.
Food can prevent certain medicines being absorbed into the bloodstream. Bertalan Szürös, CC BY-NC-ND