Body

Researchers are a step closer to understanding the risk factors associated with endometriosis thanks to a new study.

Dr Jonathan McGuane, from theUniversity of Adelaide's Robinson Research Institute says they discovered an association between contact with seminal fluid and the development of endometriosis.

"In laboratory studies, our research found that seminal fluid (a major component of semen) enhances the survival and growth of endometriosis lesions," says Dr McGuane, co-lead author on the paper.

Continually producing sperm over a long time is important to procreate the next generation. Researchers of the National Institute for Basic Biology, National Institutes of Natural Sciences in Japan, Ms. Kanako Ikami and Prof. Shosei Yoshida, and their colleagues have revealed that there are differences in reactivity to retinoic acid in spermatogonial stem cells, and these differences are a key factor to the persistence of sperm production with inexhaustible stem cells. This research was published in the May 1st issue of Development.

Recently there has been much interest in the potential for exploring new therapeutic uses for existing drugs, in part, because existing medications are relatively inexpensive and have known side effect profiles. A new study investigated whether lung cancer patients who received statins had improved cancer outcomes.

New research published today in Diabetologia (the journal of the European Association for the Study of Diabetes) indicates that for each 5% increase of a person's total energy intake provided by sweet drinks including soft drinks, the risk of developing type 2 diabetes may increase by 18%. However, the study also estimates that replacing the daily consumption of one serving of a sugary drink with either water or unsweetened tea or coffee can lower the risk of developing diabetes by between 14% and 25%.

A new study suggests that engaging in low intensity activities such as standing may not be enough to offset the health hazards of sitting for long periods of time. On the bright side, adding two minutes of walking each hour to your routine just might do the trick. These findings were published in the Clinical Journal of the American Society of Nephrology (CJASN).

"The word, virus, connotes morbidity and mortality, but that bad reputation is not universally deserved," said Marilyn Roossinck, PhD, Professor of Plant Pathology and Environmental Microbiology and Biology at the Pennsylvania State University, University Park. "Viruses, like bacteria, can be important beneficial microbes in human health and in agriculture," she said. Her review of the current literature on beneficial viruses appeared ahead of print April 24 in the Journal of Virology, which is published by the American Society for Microbiology.

A study tying the aging process to the deterioration of tightly packaged bundles of cellular DNA could lead to methods of preventing and treating age-related diseases such as cancer, diabetes and Alzheimer's disease, as detailed April 30, 2015, in Science.

In the study, scientists at the Salk Institute and the Chinese Academy of Science found that the genetic mutations underlying Werner syndrome, a disorder that leads to premature aging and death, resulted in the deterioration of bundles of DNA known as heterochromatin.

Few doctors are prescribing a low-cost drug that has been proven effective in preventing the onset of diabetes, according to a study in Annals of Internal Medicine which found that only 3.7 percent of U.S. adults with pre-diabetes were prescribed metformin during a recent three-year period.

The human body is a cross between a factory and a construction zone -- at least on the cellular level. Certain proteins act as project managers, which direct a wide variety of processes and determine the fate of the cell as a whole.

Individuals with Type 2 Diabetes have difficulty regulating their glucose -- or blood sugar -- levels, particularly after meals. Now, University of Missouri researchers have found that Type 2 diabetics can eat more protein at breakfast to help reduce glucose spikes at both breakfast and lunch.

Human chromosomes are much bigger and more complex than proteins, but like proteins, they appear to fold and unfold in an orderly process as they carry out their functions in cells.

Rice University biophysicist Peter Wolynes and postdoctoral fellow Bin Zhang have embarked upon a long project to define that order. They hope to develop a theory that predicts the folding mechanisms and resulting structures of chromosomes in the same general way Wolynes helped revolutionize the view of protein folding through the concept of energy landscapes.

Genetic testing of Iñupiat people currently living in Alaska's North Slope is helping Northwestern University scientists fill in the blanks on questions about the migration patterns and ancestral pool of the people who populated the North American Arctic over the last 5,000 years.

Weight loss is never easy, but it's important for overweight people with type 2 diabetes seeking to control their blood sugar levels and optimize their health. A small clinical trial among such patients led by Joslin Diabetes Center and Brigham and Women's Hospital researchers now has shown that two approaches--adjustable gastric band surgery and an intensive group-based medical diabetes and weight management program--achieved similar improvements in controlling blood sugar levels after one year.

Scientists have mapped the human genes triggered by the phytonutrients in soy, revealing the complex role the legume plays in both preventing and advancing breast cancer.

Researchers at the University of Illinois found that the compounds in minimally processed soy flour stimulate genes that suppress cancer, while purified soy isoflavones stimulate oncogenes that promote tumor growth. The paper, available online, was accepted for publication in the journal Molecular Nutrition and Food Research.

Cystic fibrosis is an inherited, life-threatening disorder that damages the lungs and digestive system. It is most commonly caused by a mutation in the cystic fibrosis gene known as F508del. The disorder has no cure, and treatment typically consists of symptom management. Previous attempts to treat the disease through gene therapy have been unsuccessful.