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The sight of healthcare workers wearing personal protective equipment (PPE) to protect against transmission of SARS-CoV-2 is something the world has become accustomed to. However, a new study analysing the impact of PPE staff shows that the number and variety of issues they experience increases as their time in PPE without a break increases, ranging from tiredness and headaches in the first hour to nausea, vomiting and dizziness as they head towards four hours continuously in PPE.
A brain pressure disorder that especially affects women, causing severe headaches and sometimes permanent sight loss, has risen six-fold in 15 years, and is linked to obesity and deprivation, a new study by Swansea University researchers has shown.
Rates of emergency hospital admissions in Wales for people with the disorder were also five times higher than for those without.
Schools are closing again in response to surging levels of COVID-19 infection, but staging randomised trials when students eventually return could help to clarify uncertainties around when we should send children back to the classroom, according to a new study.
Experts say that school reopening policies currently lack a rigorous evidence base - leading to wide variation in policies around the world, but staging cluster randomized trials (CRT) would create a body of evidence to help policy makers take the right decisions.
The colons of African-Americans and people of European descent age differently, new research reveals, helping explain racial disparities in colorectal cancer - the cancer that killed beloved "Black Panther" star Chadwick Boseman at only 43.
Philadelphia, January 21, 2021 - Researchers have developed a new integrated genetic/epigenetic DNA-sequencing protocol known as MultiMMR that can identify the presence and cause of mismatch repair (MMR) deficiency in a single test from a small sample of DNA in colon, endometrial, and other cancers. This alternative to complex, multi-step testing workflows can also determine causes of MMR deficiency often missed by current clinical tests.
A pain management regimen comprised mostly of over-the-counter medication reduced opioid exposure in trauma patients while achieving equal levels of pain control, according to a new study by physician-researchers at The University of Texas Health Science Center at Houston (UTHealth.)
Results of the study, which was conducted at the Red Duke Trauma Institute at Memorial Hermann-Texas Medical Center, were published today in the Journal of American College of Surgeons.
Study defines small-cell lung cancer subtypes and distinct therapeutic vulnerabilities for each type
HOUSTON -- Researchers from The University of Texas MD Anderson Cancer Center have developed the first comprehensive framework to classify small-cell lung cancer (SCLC) into four unique subtypes, based on gene expression, and have identified potential therapeutic targets for each type in a study published today in Cancer Cell.
Vaccinating people over 60 is the most effective way to mitigate mortality from COVID-19, a new age-based modeling study suggests. Although vaccination of younger adults is projected to avert the greatest incidence of disease, vaccinating older adults will most effectively reduce deaths, the analysis shows. Less than one year after SARS-CoV-2 was identified, deployment of multiple vaccines against the virus has been initiated in several countries. Although vaccine production is being rapidly scaled up, demand will exceed supply for the next several months.
Vaccinating older adults for COVID-19 first will save substantially more U.S. lives than prioritizing other age groups, and the slower the vaccine rollout and more widespread the virus, the more critical it is to bring them to the front of the line.
That's one key takeaway from a new University of Colorado Boulder paper, published today in the journal Science, which uses mathematical modeling to make projections about how different distribution strategies would play out in countries around the globe.
Medicated drops may help close small macular holes over a two- to eight-week period, allowing some people to avoid surgery to fix the vision problem, a new study suggests.
The findings, based on a retrospective multicenter case series published Dec. 15, 2020, in Ophthalmology Retina, could lead to a better understanding of which patients may benefit from the treatment, as well as the timeline of the treatment's effectiveness.
Researchers at Vanderbilt University Medical Center and colleagues have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences.
Their findings, published recently in the American Journal of Human Genetics, may aid efforts to identify patients with COVID-19 at greatest risk for pneumonia, and enable earlier interventions to prevent severe illness and death.
CHAPEL HILL, N.C.
A recent study published in Acta Obstetricia et Gynecologica Scandinavica found that questions typically asked to new mothers to screen for depression after giving birth can also help to detect depressive symptoms and other mental disorders during early pregnancy.
The US prevalence of the autoimmune disease lupus is 72.8 cases per 100,000 individuals, according to an analysis of population-based registries. The analysis, which is published in Arthritis & Rheumatology, found that the rate is 9 times higher for females than males (128.7 vs. 14.6 per 100,000), and it's highest among American Indians/Alaska Natives and Black females.
The study's investigators estimate that in 2018, a total of 204,295 persons in the United States had lupus.
Where people die can affect the quality of their deaths and the end-of-life care that they receive. A study published in the Journal of the American Geriatrics Society found that satisfaction with end-of-life care was rated highest when individuals died at home.