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The prevalence of depression, cannabis use, and alcohol abuse increased among former smokers from 2005 to 2016 in the U.S., according to a new study published in the American Journal of Preventive Medicine. Therefore, increases in these risk factors for relapse among former smokers could threaten progress in reducing the prevalence of cigarette use. This is the first national U.S. study to focus on the prevalence and time trends of depression, marijuana use, and problematic alcohol use among former smokers.
Philadelphia, August 20, 2019 - Brain abnormalities in people at familial risk of schizophrenia and bipolar disorder emerge in unique patterns, despite the symptom and genetic overlap of the disorders, according to a study in Biological Psychiatry, published by Elsevier.
Chromatin organizes the approximately two meters of DNA present in the nucleus of every human cell so that, dependent on the cell type and state, certain genes can be activated, others repressed. The fundamental organizing unit of chromatin is the nucleosome, consisting of 146 base pairs of DNA wrapped around a histone octamer. Whenever a cell needs to adapt - for example, to respond to developmental or environmental signals or to DNA damage -, it needs to alter the accessibility of its DNA.
In 2017, some 10 million people suffered from tuberculosis and 1.6 million died of the disease. One reason why infection with Mycobacterium tuberculosis is so difficult to treat is that the bacteria can hide inside immune cells. University of Groningen scientists, together with a team from the Division of Rheumatology, immunology and Allergy led by professor D.
Was hospital move to all private rooms associated with reductions in health care-related infections?
What The Study Did: A Montreal hospital moved from an older facility with ward-type rooms to a new facility with all private rooms and this analysis examined whether that was associated with reductions in multidrug-resistant organism colonization and health care-associated infections.
Authors: Todd C. Lee, M.D., M.P.H., of McGill University in Montreal, is the corresponding author.
(doi:10.1001/jamainternmed.2019.2798)
PHILADELPHIA - Pancreatic cancer is one of the deadliest cancers, with patients surviving on average less than a year once the disease has spread. There is an urgent need to evaluate more therapeutic targets. The chemotherapeutic agent abemaciclib is effective in treating breast cancer, but there is limited preclinical evaluation of this targeted therapy in treating pancreatic cancer.
Physical fitness is a strong mortality predictor and exercise training is now considered a cornerstone in the non-pharmacological prevention and treatment of lifestyle diseases, including hypertension, type 2 diabetes and osteoporosis.
A new study from the University of Southern Denmark shows that football is a surprisingly efficient type of physical training for female prediabetes patients, with impressive effects on cardiovascular health after 16 weeks of training for 55-70-year old women with no prior football experience.
Since its approval in April 2019, dacomitinib has been available for the first-line treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR)-activating mutations. The German Institute for Quality and Efficiency in Health Care (IQWiG) now examined in an early benefit assessment whether this drug offers an added benefit for patients in comparison with the appropriate comparator therapy.
New research by Sussex scientists could be the first step towards developing a blood test to diagnose the most aggressive type of brain tumour, known as Glioblastoma.
A team from Professor Georgios Giamas' lab at the University of Sussex has identified novel biomarkers within bodily fluids, which signal the presence of the tumour.
New research shows that brief parent-targeted interventions in the primary care setting can increase communication between parents and their teens about sexual and alcohol-related behavior. This method may serve as an important strategy for parents to influence adolescent behaviors and health outcomes.
Researchers from Children's Hospital of Philadelphia published the study today in JAMA Network Open.
Researchers from Osaka University, in cooperation with the Institute for Clinical Research and medical institutes participating in the Kansai Molecular Diagnosis Network for CNS Tumors (KNBTG), conducted the largest-ever retrospective cohort study for Japanese patients with glioblastoma (GBM), proposing an underlying prognosis biomarker responsible for the survival difference between two cohorts: an original Japanese cohort and a dataset from The Cancer Genome Atlas (TCGA). Their research results were published in Acta Neuropathologica Communications.
The liver plays a vital role as a filter in the human body. But what happens when it malfunctions? Researchers from the Universities of Geneva (UNIGE) and Lausanne (UNIL), the Vaud University Hospital Centre (CHUV), the Centre for Biomedical Imaging (CIBM), the Federal Polytechnic School of Lausanne (EPFL) and the University Hospitals of Geneva (HUG), Switzerland, teamed up to perform a detailed analysis of hepatic encephalopathy, a type of brain damage caused by chronic liver disease.
ANN ARBOR, Mich. - Four in 10 parents say they are very or somewhat likely to move their child to a different provider if their doctor sees families who refuse all childhood vaccines, according to a new national poll.
Most American children receive recommended vaccines protecting them from dangerous illnesses like measles and whooping cough.
DALLAS, Aug. 19, 2019 -- People suffering from insomnia may have an increased risk of coronary artery disease, heart failure and stroke, according to new research in the American Heart Association's journal Circulation.
Imagine there were a drug that you could take soon after a heart attack that could reduce damage by protecting healthy heart muscle tissue.
"Cardiologists say that when a heart attack occurs, time is muscle," said Robert Gourdie, director of the Fralin Biomedical Research Institute at VTC Center for Heart and Reparative Medicine Research.