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Men with the BRCA2 gene fault have an increased risk of prostate cancer and could benefit from PSA (prostate specific antigen) testing* to help detect the disease earlier, according to researchers funded by Cancer Research UK**.
Previous studies have shown that PSA is not a suitable test for screening for prostate cancer in the general population, and this remains the case. There are limitations to the PSA test - including false positives, false negatives and overdiagnosis***.
Scientists have shown for the first time evidence that early sampling of blood for microorganisms in sepsis is critical to treating the common and potentially fatal condition.
In an international study including researchers from the University of British Columbia (UBC), McGill University and Harvard Medical School, scientists found that in order to better treat sepsis, emergency rooms must strictly follow sepsis guidelines, which demand trained personnel and proper equipment.
A new needle-free flu vaccine patch revved up the immune system much like a traditional flu shot without any negative side effects, according to a study published in the Journal of Investigative Dermatology. Though the research is in the early stages (the patch hasn't been tested in humans), it's an important step toward a technology that could replace needle-based vaccination methods that require administration by health care workers and biohazard waste removal.
Initial results of NRG Oncology Clinical Trial RTOG 9601 in men with biochemically recurrent prostate cancer receiving salvage radiotherapy (SRT) demonstrated improvement in OS from the addition of long-term hormone therapy to SRT. However, a secondary analysis indicates that all patients do not benefit and the addition of long-term anti-androgen therapy did not improve overall survival (OS) rates and could increase other-cause mortality (OCM) for some patients depending on pre-treatment PSA level.
WASHINGTON (Sept. 16, 2019) -- Automated external defibrillators (AEDs) are often placed in areas of low risk and may be unavailable during certain times of the day. Determining the optimal location for AEDs may lead to increased defibrillation by bystanders and increased survival in those experiencing out-of-hospital cardiac arrest (OHCA), according to research published today in the Journal of the American College of Cardiology.
Mosquitoes are more likely to acquire the dengue virus when they feed on blood with low levels of iron, researchers report in the 16 September issue of Nature Microbiology. Supplementing people's diets with iron in places where both iron deficiency anemia and dengue fever are a problem could potentially limit transmission of the disease, but there are risks.
More than 70% of U.S. adults are unaware that human papillomavirus (HPV) causes anal, penile, and oral cancers, according to an analysis led by researchers at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health and published in the current issue of JAMA Pediatrics.
Heart attack is a leading cause of death worldwide and new treatment strategies are highly sought-after. Unfortunately lasting damage to the heart muscle is not uncommon following such an event.
Published in Redox Biology, the pre-clinical study sheds new light on the potential of the acute therapy with α-TOH (vitamin E) in patients presenting with heart attack, and may ultimately offer an effective low-cost treatment.
In a follow-up study conducted in South Africa, Johns Hopkins Medicine researchers say they have evidence that hospital emergency departments (EDs) worldwide may be key strategic settings for curbing the spread of HIV infections in hard-to-reach populations if the EDs jump-start treatment and case management as well as diagnosis of the disease. A report on the findings was published in August in EClinicalMedicine.
Researchers experimentally determined a property of cadmium called the magic wavelength which is considered essential for the development of the most accurate clocks ever envisaged. The researchers hope this may permit simple and robust atomic clocks so accurate they could be used to improve our understanding of current theories and even test for new physics.
U.S. physicians are increasingly ordering medications for children for conditions that are not approved by the Food and Drug Administration, according to a Rutgers study.
The findings highlight the need for more education, research and policies addressing effective, safe pediatric drug prescribing.
A group of forager-farmers in Bolivia's tropical forests -- known for having remarkable cardiovascular health and low blood pressure -- experienced changes in body mass and diet over a nine-year period, with increased use of cooking oil the most notable dietary change.
New research presented at this year's annual meeting of the European Association for the Study of Diabetes (EASD) in Barcelona, Spain (16-20 September) shows that specialist analysis of the lens in the eye can predict patients with type 2 diabetes and impaired glucose tolerance (IGT) (also known as prediabetes, a condition that often leads to full blown of type 2 diabetes).
The research published today (Monday 16 September) in Paediatric and Perinatal Epidemiology examined whether there were any effects of taking paracetamol in mid-pregnancy and the behaviour of the offspring between the ages of 6 month and 11 years, with memory and IQ tested up until the age of 17. Paracetamol is commonly used to relieve pain during pregnancy and is recommended as the treatment of choice by the NHS.
Heart failure is an important potential complication of type 2 diabetes that occurs frequently and can lead to death or disability. Earlier this month, late-breaking trial results revealed that a new class of medications known as SGLT2 inhibitors may be helpful for patients with heart failure. These therapies may also be used in patients with diabetes to prevent heart failure from occurring in the first place. However, a way of accurately identifying which diabetes patients are most at risk for heart failure remains elusive.