Body

A simple blood test could soon become the latest monitoring tool for the early detection of melanoma in the eye.

University of Queensland scientists have discovered markers in the blood that can differentiate between a benign mole and a melanoma, while also identifying if the cancer has spread to other areas of the body.

University of Queensland Diamantina Institute's Dr Mitchell Stark said the blood test could monitor very early signs of the disease.

In June, the International Energy Agency confirmed what most experts already know: that the world should work harder to boost the use of pure hydrogen as an emissions-free energy source.

One of the challenges of creating hydrogen, however, is that it takes energy--lots of energy. The IEA says that producing all of today's hydrogen just using electricity would require 3600 TWh, which is more than is generated annually by the European Union.

The Chinese government may have been systematically misreporting the number of organs it claims it has voluntarily collected since 2010, according to new research published in BMC Medical Ethics.

In 2015 China promised the world they would no longer source organs from prisoners - their almost sole source previously.

The study, led by PhD scholar Matthew Robertson from The Australian National University (ANU), used statistical forensics on official Chinese datasets.

Subarachnoid haemorrhage is a severe stroke subtype that is caused by a rupture of a brain aneurysm, an enlargement in brain vessel wall.

Up to one in four subarachnoid haemorrhage patients die quickly after the bleed at home, on the road to a hospital, or in an emergency room. These patients never reach hospital wards and are often incorrectly diagnosed. In many countries, these sudden deaths are classified as sudden cardiac deaths since routine autopsies are rarely conducted outside Nordic countries.

An abdominal aortic aneurysm is a focal dilation of the abdominal aorta, that if not treated, tends to grow and may rupture. The most common treatment is EndoVascular Aneurysm Repair (EVAR), which requires patients to undergo lifelong postoperative surveillance based on computed tomography angiography (CTA) due to the possible appearance of complications. These complications may again lead to aneurysm dilation and rupture.

Women exposed simultaneously to stress and plastic additives late in pregnancy are at increased risk for premature birth, according to a study by Rutgers and other institutions.

The study, published in the journal Environment International, is the first to analyze a link between stress and phthalates - a group of chemicals in plastics, personal care products and electronics - and premature births. The findings are the latest in the Infant Development and the Environment Study, which tracked 783 women throughout their pregnancies between 2010 and 2012.

Washington, DC, November 14, 2019- A study in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP), published by Elsevier, reports that home-visiting by trained community workers during and after pregnancy can improve mother-child interactions in the first years of life.

ANN ARBOR--Everyone knows that gaining excess weight during one pregnancy is bad, but clinicians rarely consider weight gains and losses from one pregnancy to the next--especially in normal-weight women.

But researchers from Marquette University and the University of Michigan found that among normal-weight women, fluctuating weight gain and loss in the first pregnancy is often repeated in subsequent pregnancies--and is associated with higher risk of several pregnancy-related complications.

WINSTON-SALEM, N.C. - Nov. 14, 2019 - Scientists have reported a new approach to treating lung cancer with inhaled nanoparticles developed at Wake Forest School of Medicine, part of Wake Forest Baptist Health.

In this proof of concept study, Dawen Zhao, M.D., Ph.D., associate professor of biomedical engineering at Wake Forest School of Medicine, used a mouse model to determine if metastatic lung tumors responded to an inhalable nanoparticle-immunotherapy system combined with the radiation therapy that is commonly used to treat lung cancer.

Philadelphia, Pa. - (November 18, 2019) - An upcoming clinical trial at Children's National Hospital will harness cardiopulmonary bypass as a delivery mechanism for a novel intervention designed to stimulate brain growth and repair in children who undergo cardiac surgery for congenital heart disease.

Montreal, November 14, 2019 -- In Canada, 171,900 people injected drugs in 2016, up from 130,000 in 2011. In a study published in the American Journal of Public Health, researchers at the University of Montreal Hospital Research Centre (CRCHUM) estimated, using multiplier methods, the number of people who injected drugs in 11 of the 13 Canadian provinces (Nunavut and Northwest Territories not included) and reported a 30-per-cent increase in the period studied.

DUARTE, Calif. -- The first CAR T cell therapy targeting the B cell-activating factor receptor on cancerous cells eradicated CD19-targeted therapy-resistant human leukemia and lymphoma cells in animal models, according to City of Hope research published today in Science Translational Medicine. The new therapy will be used in a clinical trial next year for patients who relapsed after CD19 immunotherapy treatments and may potentially be used as a first-line of CAR T cell therapy treatment.

Web-based and digital-app services that offer oral contraception appear to be overall safe and efficient, according to the findings of a secret-shopper-style study conducted by researchers at Harvard Medical School and UC Davis that analyzed the birth control prescription services of nine U.S. vendors.

UCLA RESEARCH ALERT

FINDINGS

Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new drug delivery pathway that may help stop tumor growth and keep cancer from coming back in mice. In the preclinical study, the team found that they could reengineer adipocytes -- fat cells that feed fatty acids energy needed to promote tumor growth and metastasis -- to reverse their malignant role on tumor development and deliver cancer-fighting drugs directly to the tumor microenvironment.

BACKGROUND

Bottom Line: Among 123,000 patients in the U.S. Department of Veterans Affairs health system with newly diagnosed diabetes, 23% had mental health or substance use disorder diagnoses and that prior engagement with the health care system may be associated with a lower severity of complications for a few years after the onset of diabetes. More than 90% of patients with mental health or substance use disorders had primary care visits before diabetes was diagnosed compared with 58 percent of patients without those disorders.