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Using a modified natural substance along with current approaches could improve colon cancer treatment, according to findings by University of California, Irvine biologists. The discovery comes from their research into the role of an amino acid in tumor development and a potential method for reversing the process. Their paper appears in Nature Cancer. The disease is the second-leading cause of cancer-related deaths in the United States.
It is clear that we must prioritize identifying and alleviating the conditions that made the Covid-19 pandemic possible. Even as it rages, scientists are already asking if it is more than just a virus, but rather a symptom emerging from something much deeper, a nonlinear dynamical system of coupled pathologies underlying a veneer of "progress" in an increasingly fragile, volatile, hyperconnected world.
Hospitals can prepare for a surge of patients critically ill with COVID-19, but it will require hospital leaders, practitioners and regional officials to adopt drastic measures that challenge the standard way of providing care, according to a new RAND Corporation report.
A larger thigh circumference may be associated with lower blood pressure and a reduced risk of heart disease in people with obesity, according to a study published in Endocrine Connections. In overweight and obese Chinese men and women, larger thigh circumferences were associated with lower blood pressure. These findings suggest that carrying more weight on the thighs may be a marker of better heart health in Chinese obese and overweight people, who are at a greater risk of heart disease.
DOCTORS and nurses on the COVID-19 frontline are spending many hours a day wearing face masks, and many members of the general public are doing the same. But although the devices offer invaluable protection, they can be the cause of significant skin damage through sweating and the rubbing of the masks against the nose.
Skincare experts at the University of Huddersfield are warning about the risks and are suggesting remedies.
Experts writing in the Journal of Parkinson's Disease discuss potentially grave consequences for Parkinson's disease patients related to social distancing, but also opportunities like new avenues for research and initiatives that may offer positive help and support
Deaths of children and adolescents in China due to infectious diseases were becoming rare prior to the covid-19 pandemic, according to a new study.
Quarantinable conditions with high death rates such as cholera and plague had effectively disappeared and many traditional and vaccine-preventable infectious diseases of childhood including diarrhoea, measles and rubella became uncommon.
Nagano prefecture is home to a group of people effected with a rare genetic neurodegenerative disorder called familial amyloid polyneuropathies (FAP). This disease impacts the gene encoding protein transthyretin (TTR) which is produced in the liver and also eyes. Liver transplants are often a treatment for this disease, but severe eyesight problems such as cloudiness and glaucoma remains, despite such procedures. This research is a retrospective observational study of what ophthalmologists have experienced in their practice over the years.
Researchers from the Center for Precision Disease Modeling at the University of Maryland School of Medicine (UMSOM) have uncovered a mechanism that appears to explain how certain genetic mutations give rise to a rare genetic kidney disorder called nephrotic syndrome. Using a drosophila (fruit fly) model, they found mutations in genes that code for certain proteins lead to a disruption of the recycling of the cell membrane.
COPD, short for chronic obstructive pulmonary disease, is linked to a heightened risk of lung cancer in people who have never smoked, indicates research published online in the journal Thorax.
The risk is on a par with that of smokers without chronic lung disease, the findings indicate.
COPD is an umbrella term for respiratory conditions that narrow the airways, such as bronchitis and emphysema. Smoking is the main risk factor for COPD, which itself is associated with a heightened risk of developing lung cancer.
Many patients previously diagnosed with a penicillin allergy can have their allergy label removed after testing and safely undergo treatment with penicillin medications, according to a study published in American Journal of Respiratory and Critical Care Medicine.
Few novel or emerging infectious diseases have posed such vital ethical challenges so quickly and dramatically as the novel coronavirus. An early-view essay in the March-April 2020 Hastings Center Report offers guidance at a time when health care institutions and governments are desperately confronting these challenges.
The COVID-19 pandemic has presented challenges to many health care systems across the globe.
As some consider treating coronavirus patients with a combination of the malaria drug hydroxychloroquine and the antibiotic azithromycin, cardiologists are advising caution because both medications can increase the risk for dangerous abnormal heart rhythms.