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Results of the phase III Inter-B-NHL-ritux 2010 clinical trial reported today in the New England Journal of Medicine show 95 percent three-year survival for pediatric patients with advanced B-cell non-Hodgkin lymphoma treated with the addition of anti-cancer immunotherapy rituximab to standard chemotherapy.
Researchers in the Department of Biomedical Engineering at Texas A&M University are working on an entirely new way to detect blood clots, especially in pediatric patients.
GRAND RAPIDS, Mich. (June 3, 2020) -- Van Andel Institute scientists have revealed the first known atomic structure of a "molecular machine" responsible for installing critical signaling proteins into cellular membranes.
The findings, published today in Nature, shed new light on how this process works, and lay the foundation for potential future therapies for diseases like cancer, Alzheimer's and cystic fibrosis.
UNIVERSITY PARK, Pa. -- Antibiotics are important drugs that can save lives, but using them too often can lead to dangerous strains of antibiotic-resistant bacteria. New Penn State research explores how to communicate risk while encouraging people to seek information on their own.
The researchers found that a brief animated video was effective in convincing participants that antibiotic use can be risky, which in turn resulted in participants viewing antibiotics as less positive or useful, and also made them feel that they needed more information about antibiotics.
Volume 11, Issue 22 of Oncotarget reported that the goal of this study was to explore the involvement of mi RNAs in beneficial effects exerted by physical activity in breast cancer prevention.
Women's risk of falling ill with cardiovascular disease, and dying from it, is lower than that of men of the same age, irrespective of where in the world they live. This is shown by a study of, in total, more than 160,000 men and women in 27 countries. Scientists at the University of Gothenburg, Sweden, are among those presenting the results.
CHICAGO --- For someone with a food or drug allergy, the risk of life-threatening anaphylactic shock lurks around every corner. A new Northwestern Medicine study shows there might be a pill that can be taken proactively to prevent mild to life-threatening anaphylaxis, no matter the cause.
WASHINGTON--Per- and polyfluoroalkyl substance (PFAS) exposure may cause menopause to occur two years earlier in women, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.
The number of heart attack patients seeking urgent hospital care has dropped by more than 50% during the COVID-19 outbreak, according to an extensive worldwide survey by the European Society of Cardiology (ESC).
Different groups of drugs are used for the treatment of rheumatic conditions. They are intended to suppress the rogue immune system which attacks its own body. It is unclear to date whether the use of immunosuppressants increases the risk of a severe course in case of an infection with the novel coronavirus SARS-CoV-2.
A recent study found that nitrogen-containing bisphosphonates (N-BPs) such as alendronate, which are widely used to treat postmenopausal osteoporosis, are linked with lower risks of pneumonia and of dying from pneumonia. The results are published in the Journal of Bone and Mineral Research.
For patients admitted to the intensive care unit in a hospital in Finland, increased workload for nurses and understaffing of nurses were linked with a higher likelihood that patients would experience multiple organ failure. The findings are published in the Journal of Advanced Nursing.
The levels of nursing workload and understaffing were at their worst on weekends.
Low-dose aspirin significantly lowers cardiovascular disease risk but increases the risk of bleeding, according to a review published in the British Journal of Clinical Pharmacology.
Investigators conducted the review because the overall balance between risks and benefits of taking aspirin has been unclear. The team pooled information from analyses of all relevant observational studies and randomized controlled trials.
A new BJS (British Journal of Surgery) study indicates that breast cancer surgery is safe for patients who are older than 70 years of age, but age can influence the decision to undergo surgery.
Most new viruses and other pathogens that arise in humans are transmitted from other animals, as in the case of the virus that causes COVID-19. A recent review published in Mammal Review examines how changes in land-use--such as deforestation, urbanization, and conversion to agriculture--have affected such transmission.