Body
Scientists have developed a new gene therapy approach that offers tremendous promise for one day treating an eye disease that leads to blindness and affects thousands of people across the globe.
Researchers from Trinity College Dublin and University College London (UCL) teamed up to pool their expertise in genetics, virology and ophthalmology, beginning the journey towards a new treatment for a group of eye diseases collectively referred to as retinitis pigmentosa (RP). Their exciting results are published today in leading journal, Stem Cell Reports.
- Urging the healthcare and regulatory community to use the terms as published for the different subtypes of MS and for describing disease activity, which is critical for selecting clinical trial participants
Scientists have developed a new test that can help identify people who are likely to develop hepatocellular carcinoma (HCC), the most common form of liver cancer. The approach uses a simple blood test to check for the patient's previous exposure to certain viruses.
Mass burials are common remnants of the many plague outbreaks that ravaged Medieval Europe. A number of these graveyards are well documented in historical sources, but the locations of most, and the victims they contain, have been lost to the pages of time. In Vilnius, Lithuania, one such cemetery was found in a typical way: accidental discovery during a routine city construction project.
In conventional ultrasounds, variations in soft tissue structure distort ultrasound wavefronts. They blur the image and can hence prove detrimental to medical diagnosis. Researchers at the Institut Langevin (CNRS/ESPCI Paris-PSL)* have developed a new non-invasive ultrasound method that avoids such aberrations.
Men who regularly used a free web resource made significantly more health changes than men who did not, finds a new study from the University of British Columbia and Intensions Consulting.
The researchers compared differences in behaviour among 863 men who accessed DontChangeMuch.ca and a benchmark sample of 2,000 Canadian men who had not. They found 75 per cent of regular users of the site reported improving their eating habits, and 70 per cent said they were engaging in more sports or exercise.
Patients who go into shock caused by sepsis (septic shock) are treated with the antihypotensive agent norepinephrine. Researchers from Radboud university medical center published results in today's American Journal of Respiratory and Critical Care Medicine revealing that its use is not without drawbacks: the drug disrupts the immune system and increases susceptibility to infections. This may have negative consequences for patients. Research into alternatives is therefore justified.
Inoperable malignant pleural mesothelioma, is a rare and aggressive cancer of the protective lining of the lungs, or pleura, often caused by exposure to asbestos. At the annual meeting of the American Society of Clinical Oncology (ASCO), held virtually from May 29-31, 2020, a researcher from the Johns Hopkins Kimmel Cancer Center presented findings from a multicenter study that evaluated the efficacy of an immunotherapy-plus-chemotherapy combination for the disease.
Scientists have found a potential new way to promote blood clotting that could be used to help develop treatments for Von Willebrand Disease, the most common genetic bleeding disorder.
The study, led by researchers at RCSI University of Medicine and Health Sciences, is published in the Journal of Thrombosis and Haemostasis.
Research from the Department of Kinesiology at McMaster University has found that the practical advantages of high-intensity interval training (HIIT), or short bursts of all-out exercise, could be especially beneficial for people who have experienced spinal cord injuries (SCI).
While many studies have proven the benefits of HIIT for the able-bodied, much less is known about its impact - for better or worse -- on the SCI population.
DALLAS - June 11, 2020 - Shelter-in-place orders to reduce the spread of COVID-19 put unusual strains on people with obesity, making it more difficult for them to eat properly and manage their weight, according to a UT Southwestern study.
WASHINGTON--Eating a late dinner may contribute to weight gain and high blood sugar, according to a small study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.
Dopamine is a neurotransmitter involved in everything from higher cognitive functions to motor control, motivation, arousal, reinforcement, and sexual gratification, the receptors it acts on have been a longstanding target for treating disorders like Parkinson's disease, which is caused by the degeneration of dopamine-using neurons that control movement.
A scalable "lab-on-a-chip" technology based on inkjet printing methods detected breast cancer in plasma samples from patients with more than 90% accuracy, according to a new study. The new chips, which sniffed out both early-stage and metastatic tumors when tested using plasma from 100 individuals, could one day allow clinicians to detect new cancers and monitor existing tumors less invasively compared with current diagnostic methods.
A good vitamin D status is beneficial both in cancer prevention and in the prognosis of several cancers, according to a new research review. The anti-cancer effects of vitamin D are especially pronounced in the prevention and treatment of colon cancer and blood cancers. In addition, high vitamin D responsiveness can be linked to a smaller cancer risk. Vitamin D responsiveness varies between individuals, affecting their need for vitamin D supplementation.