Body

(LOS ANGELES) - Successful tissue regeneration can have major benefits in healing injuries or replacing portions of diseased or damaged tissue in bone, skin, the nervous system and in organs such as the muscle, kidney, liver, lung and heart. But the effectiveness of the body's own system for repairing such damage can vary greatly, depending on the kind of tissue involved and its location. Tissue engineers have been working to address these limitations by creating substances called biomaterials, which can be used in various ways to boost the body's ability to heal.

Study after study has shown that statins can prevent heart attacks, strokes and death in middle-aged adults. But in 28 major clinical trials of statins, only 2 percent of participants have been 75 years or older. This means that even though older adults are at greater risk of heart disease and death, there is scant data on whether statins should be prescribed for them. A new study led by investigators from Brigham and Women's Hospital and VA Boston Healthcare System leverages national data from the U.S.

DURHAM, N.C. - Researchers from the HIV Prevention Trials Network (HPTN) announced today that the HPTN 083 clinical trial showed that a pre-exposure prophylaxis (PrEP) regimen containing long-acting cabotegravir (CAB LA) injected once every 8 weeks was superior to daily oral tenofovir/emtricitabine (TDF/FTC) for HIV prevention among cisgender men and transgender women who have sex with men. The results were reported at the 23rd International AIDS Conference (AIDS 2020: Virtual).

Interstitial lung diseases (ILDs) are a common and serious consequence of rheumatoid arthritis (RA). The prevalence varies depending on population and diagnostic method, but at least 5 to 10 percent of all RA patients suffer from this condition, which leads to inflammatory changes in lung tissue and pulmonary alveoli. It is accompanied by a dry cough and breathing difficulties. A severe course may lead to scarring of lung tissue, which is referred to as lung fibrosis. This may lead to a life-long dependency on oxygen supply or even a lung transplant.

Amid news that the United States has bought up virtually the entire global supply of remdesivir, a new Boston University School of Public Health (BUSPH) study outlines how the drug could save lives in countries with less hospital capacity, such as South Africa, where COVID-19 is beginning to overwhelm intensive care units (ICUs).

Recent research has suggested that remdesivir can reduce deaths from COVID-19 by as much as 30%, but has a more significant effect on how long patients need intensive care, from an average of 15 days down to an average of 11 days.

Philadelphia, July 7, 2020 - Researchers have previously identified brain structural signatures associated with individual neurological diseases using techniques such as magnetic resonance imaging (MRI). In a new study, a team of scientists based in Germany has compared data from multiple studies to find brain structural abnormalities shared between four different neuropsychiatric conditions. The researchers also found brain signatures that were unique to individual conditions.

New Rochelle, NY, July 7, 2020--Fathers' prepartum social media posts can predict their risk of postpartum depression. A predictive model based on machine learning is described in the peer-reviewed journal Cyberpsychology, Behavior, and Social Networking. Click here to read the article now.

Fathers' social media posts were evaluated for changes in behavior (engagement with the platform), emotions, linguistic style, and discussion topics following the birth of their child.

WASHINGTON--Extreme ocean surface waves with a devastating impact on coastal communities and infrastructure in the Arctic may become larger due to climate change, according to a new study.

The new research projects the annual maximum wave height will get up to two to three times higher than it is now along coastlines in areas of the Arctic such as along the Beaufort Sea. The new study in AGU's Journal of Geophysical Research: Oceans suggests waves could get up to 2 meters (6.6 feet) higher than current wave heights by the end of the century.

An analysis of data from more than 1,300 women followed prospectively through pregnancy found that women with lower levels of the essential mineral manganese in early pregnancy were more likely to develop the serious high blood pressure syndrome called preeclampsia in late pregnancy, according to a new study led by researchers from Johns Hopkins Bloomberg School of Public Health.

The study, published online in the journal Epidemiology, suggests the possibility that boosting manganese levels in women before and during pregnancy could potentially reduce preeclampsia risk.

Boston, Mass. - Early in the COVID-19 pandemic, widespread cancellations of electively-scheduled or "non-emergency" operations were implemented to free up hospital beds and conserve protective equipment for health care workers. For some conditions, including cancer, timely surgery is critical for patients' survival. In a new study published in the Journal of Gastrointestinal Surgery, a team of investigators at Beth Israel Deaconess Medical Center (BIDMC) examined the effects of delaying surgery for gastrointestinal cancers.

7 July 2020: Fifteen years ago a large population study from Denmark found a significantly increased risk of cerebral palsy in infants born as a result of assisted reproduction.(1) Although the absolute risk was small, such studies at this time made cerebral palsy the greatest developmental birth defect risk associated with IVF, and a concern in its overall safety profile.

No matter how close parks are to home, perceptions of park-centered crime may keep New Yorkers from using them.

Researchers at NYU Grossman School of Medicine found that New Yorkers are more likely to exercise in a park if they believe they live very close to it. In turn, they feel less anxious and less depressed the more often they exercise there -- but only if they are not concerned about being safe.

Gene coding regions constitute 2% of the human genome. St. Jude Children's Research Hospital scientists have developed a computational tool to identify alterations that drive tumor formation in the remaining 98% of the genome. The method will aid discovery of oncogenes and advances in precision medicine for children and adults with cancer.

A new study at Intermountain Primary Children's Hospital in Salt Lake City has found that follow-up appointments for hospitalized children treated for childhood bronchitis are often not necessary, and that switching from mandatory to "as-needed" follow-up care can save families from unnecessary medical care and expense - and may help guide treatment during the COVID-19 pandemic.

The study is published in Monday's issue of JAMA Pediatrics.