The spreading of cancer cells from one part of the body to another, a process known as metastasis, is the leading cause of death among cancer patients. A study published April 26 in Biophysical Journal now reveals why some cancer cells may be more metastatic than others. The findings show that breast cancer cells spread to other parts of the body by sliding around other cells blocking their escape route out of the original tumor.
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LA JOLLA, CA - April 26, 2016 - For the first time, scientists at The Scripps Research Institute (TSRI) have solved the structure of the biological machinery used by a common virus to recognize and attack human host cells.
The new structure gives scientists the first view of the glycoprotein of lymphocytic choriomeningitis virus (LCMV), a virus present on every continent except Antarctica. Not only does the research reveal important traits in LCMV, it also points to possible drug targets on LCMV's close relative: Lassa virus.
Researchers look for causes of unexpected early bladder cancer recurrence after laparoscopic surgery
New York, NY, April 26, 2016 - Although laparoscopic radical cystectomy (LRC) and robotic assisted radical cystectomy (RARC) continue to grow in popularity and are successful in the treatment of bladder cancer, they are still considered experimental approaches. Using data collected by the Section of Uro-Technology of the European Association of Urology (ESUT), a team of researchers found that about 5% of patients experienced unexpected relapses of cancer after LRC, even with favorable pathology. Their results are reported in The Journal of Urology®.
The rise of antibiotic resistant bacterial pathogens is an increasingly global threat to public health. In the United States alone antibiotic resistant bacterial pathogens kill thousands every year.
But non-antibiotic therapeutic drugs already approved for other purposes in people could be effective in fighting the antibiotic-resistant pathogens, according to a new study from researchers at The University of Texas Medical Branch at Galveston.
(Boston)--About half of American women have dense breasts, which makes it harder for mammograms to identify cancer and add to a woman's risk for cancer. Nearly half of U.S. states have passed legislation requiring women to be notified of their breast density when they receive mammogram results, despite no scientific evidence or guidelines for appropriate care for women with dense breasts.
Among female registered nurses, working a rotating night shift for 5 years or more was associated with a small increase in the risk of coronary heart disease, according to a study appearing in the April 26 issue of JAMA.
In a study appearing in the April 26 issue of JAMA, Elizabeth A. Rafferty, M.D., formerly of Massachusetts General Hospital, Boston, and colleagues evaluated the screening performance of digital mammography combined with tomosynthesis (a type of imaging) compared with digital mammography alone for women with varying levels of breast density.
In a study appearing in the April 26 issue of JAMA, Nancy R. Kressin, Ph.D., of the Veterans Affairs Boston Healthcare System, Boston University School of Medicine, and colleagues examined the content, readability, and understandability of dense breast notifications sent to women following screening mammography.
CINCINNATI--Cancer researchers at the University of Cincinnati (UC) have found a particular signaling route in microRNA (miR-22) that could lead to targets for acute myeloid leukemia, the most common type of fast-growing cancer of the blood and bone marrow.
These findings are being published in the April 26 issue of the online journal Nature Communications.
Women in sub-Saharan Africa who use modern contraceptives are more likely to be tested for HIV than those who do not, according to a study published April 25, 2016 in the open-access journal PLOS ONE by Katherine Center from the University of Arizona and colleagues.
A new NYU Steinhardt study published in the journal AERA Open looks at income-based gaps in educational attainment. While the difference in high school graduation rates between high- and low-income students shrunk, inequality may have shifted to higher education, with gaps growing in college attendance and completion.
A team of researchers led by the University of Leicester has shed new light on how the regulation machinery that controls gene expression works by characterising a complex known as the NuRD complex.
The study, led by John Schwabe, Professor of Structural Biology and Head of Department of Molecular and Cell Biology at the University of Leicester and published in the journal eLIFE, focuses on three protein components which make up the core of the NuRD complex: MTA1, RBBP4 and HDAC1.
Chewbacca, the fictional 'Star Wars' character, has given his name to a new species of flightless beetle, discovered in New Britain, Papua New Guinea. Although Trigonopterus chewbacca was only one of the four black new weevil beetles found during the expedition, it stood out with its curious scales, which made the authors think of Han Solo's loyal companion.
Usher syndrome (USH) is characterized by hearing loss or deafness at birth and progressive vision loss, and is the most common cause of inherited dual sensory deficit. No treatment is currently available to stop or slow the progression of vision or hearing loss in USH3, one of three clinical classifications for USH that are further divided into subtypes and all associated with different genes.
Seven international tobacco control experts urged government regulators to avoid heavy-handed condemnation of e-cigarette use, in a study published online today in the journal Addiction.
The researchers noted that regulations of e-cigarettes are clearly needed, but that governments need to weigh growing evidence of the benefits e-cigarettes provide in helping some addicted cigarette smokers quit against the potential for harm if non-smokers take up vaping, the term commonly used to describe use of e-cigarettes.