Under normal circumstances, the immune system recognizes and successfully fights cancer cells, eliminating them as they develop. However, sometimes the process breaks down and tumors form, and now we know why. Researchers at the Texas A&M Health Science Center found that when cancer cells are able to block the function of a gene called NLRC5, they are able to evade the immune system and proliferate, according to research published today in the Proceedings of the National Academy of Sciences (PNAS).
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EAST LANSING, Mich. -- Only about 65 percent of homicides in the United States are solved - down 15 percent from the mid-1970s - but a new study led by a Michigan State University criminologist examines how some police departments are getting it right.
Sometimes the one thing we want isn't available and we have to settle for second best--instead of picking the closest substitute, new research suggests we'd be better off picking a not-so-similar alternative.
Findings from a series of studies published in Psychological Science, a journal of the Association for Psychological Science, indicate that even though people tend to prefer the option that's most similar to the item they can't have, they're likely to be more satisfied with the option that diverges a bit.
Some strange creatures cropped up in the wake of one of Earth's biggest mass extinctions 252 million years ago. In 2014, scientists discovered a bizarre fossil--a crocodile-sized sea-dwelling reptile, Atopodentatus unicus, that lived 242 million years ago in what today is southwestern China. Its head was poorly preserved, but it seemed to have a flamingo-like beak. However, in a paper published May 6 in Science Advances, Dr.
After years of increases, the rates of children who are overweight or obese are declining in Canada, according to new research in CMAJ (Canadian Medical Association Journal)
Between 1978 and 2004, there was a significant increase in Canada in the rates of children who are obese or overweight aged 2 to 17 years, from 23.3% to 34.7%, using the World Health Organization's (WHO) revised growth curves.
ANN ARBOR, Mich. - Researchers from across the globe have joined together to improve understanding about one of the most rare -- and lethal -- types of cancer.
Teams from 39 institutions in Europe, North America, South America and Australia collected and analyzed 91 samples of adrenocortical carcinoma. They performed a comprehensive genomic analysis as part of The Cancer Genome Atlas Research Network.
A diagnostic test used by hospitals says a recently isolated strain of bacteria is susceptible to the last resort antibiotic colistin. But the strain actually ignores treatment with colistin, causing lethal infections in animals.
Through "heteroresistance," a genetically identical subpopulation of antibiotic-resistant bacteria can lurk within a crowd of antibiotic-susceptible bacteria. The phenomenon could be causing unexplained treatment failures in the clinic and highlights the need for more sensitive diagnostic tests, researchers say.
An extra $73 billion was spent between 2010 and 2012 on brand name medications and the practice of therapeutic substitution (substituting chemically different compounds within the same class of drugs for one another) could help to drive down those costs, according to a new study published online by JAMA Internal Medicine.
Therapeutic substitution is a controversial way to improve the efficiency of the pharmaceutical market because it is opposed by many physician organizations as an attack on physician autonomy.
Daily consumption of artificially sweetened beverages by women during pregnancy may be associated with increased infant body mass index (BMI) and may be associated with an increased risk of being overweight in early childhood, according to an article published online by JAMA Pediatrics.
CAMBRIDGE, MA -- Scientists at MIT, Massachusetts General Hospital, Living Proof, and Olivo Labs have developed a new material that can temporarily protect and tighten skin, and smooth wrinkles. With further development, it could also be used to deliver drugs to help treat skin conditions such as eczema and other types of dermatitis.
WASHINGTON -- Evidence is mounting that the current outbreak of yellow fever is becoming the latest global health emergency, say two Georgetown University professors who call on the World Health Organization to convene an emergency committee under the International Health Regulations. In addition, with frequent emerging epidemics, they call for the creation of a "standing emergency committee" to be prepared for future health emergencies.
As governments and researchers race to develop policies and technologies to make energy production more sustainable and mitigate climate change, they need to remember that the most sophisticated endeavors won't work if they're not adopted.
Researchers from several major US universities and ITMO University in Russia have identified a number of new driver mutations in lung cancer cells that may be responsive to genomically targeted therapies and to immunotherapy.
An Otago-led team of scientists using techniques from the field of dentistry is shedding new light on the evolution of walruses, fur seals and sea lions. The researchers have cast further doubt on previous claims that an ancient "killer walrus" was a marine mammal eater.
Women suffering from extreme morning sickness often take Zofran (ondansetron) to combat their debilitating nausea and vomiting. However, two studies have found that the drug may increase risk of heart defects and cleft palate in children exposed in utero.