Body

Ann Arbor, MI, June 7, 2016 - An extensive, long-term study of Danish children followed into adulthood shows that moving to a new home during childhood increases the likelihood of multiple adverse outcomes later in life. This unique residential mobility study of 1.4 million people tracked from their 15th birthdays until their early forties appears in the American Journal of Preventive Medicine.

The presence of high saturated fatty acids in breast tissue may be a useful indicator of cancer in postmenopausal women, according to a new study by researchers at NYU Langone Medical Center, published online June 7 in Radiology, a journal of the Radiological Society of North America.

Women are almost twice as likely to experience anxiety as men, according to a review of existing scientific literature, led by the University of Cambridge. The study also found that people from Western Europe and North America are more likely to suffer from anxiety than people from other cultures.

The review, published today in the journal Brain and Behavior, also highlighted how anxiety disorders often provide a double burden on people experiencing other health-related problems, such as heart disease, cancer and even pregnancy.

A new drug that harnesses the immune system to attack tumors is highly effective against advanced bladder cancer, according to the results of an international clinical trial to be presented June 5 at the annual meeting of the American Society for Clinical Oncology (ASCO).

ABSTRACT: 4501

The immune checkpoint blockade drug nivolumab reduced tumor burden in 24.4 percent of patients with metastatic bladder cancer, regardless of whether their tumors had a biomarker related to the drug's target, according to clinical trial results from The University of Texas MD Anderson Cancer Center. The study will be presented Sunday, June 5, 2016 at the 2016 American Society of Clinical Oncology Annual Meeting.

ABSTRACT: 3503

In the first-ever clinical trial for metastatic patients previously treated for the disease, research led by The University of Texas MD Anderson Cancer Center found that the immune checkpoint blockade nivolumab shows promise for the majority of patients with squamous cell carcinoma of the anal canal (SCCA).

ABSTRACTS: 5506, 5502, 1506

Advances that could change gynecologic cancer standard-of-care treatments are the centerpiece of key studies being presented by researchers from The University of Texas MD Anderson Cancer Center's Department of Gynecologic Oncology and Reproductive Medicine at the 2016 Annual Meeting of the American Society of Clinical Oncology (ASCO).

Combining Targeted Cancer Therapies Everolimus and Letrozole with Diabetes Drug Metformin Shows Clinical Benefits for Advanced/Recurrent Endometrial Cancer

Hispanic white and non-Hispanic black cancer patients between ages 15 and 29 may be more likely than same-aged white patients to die of their disease, according to a University of Colorado Cancer Center study presented at the American Society for Clinical Oncology (ASCO) Annual Meeting 2016. The finding is partially but not wholly explained by socioeconomic status, meaning that in addition to the health risks associated with low socioeconomic status or stage of presentation, there are additional health risks associated specifically with these racial/ethnic identities.

AN expandable tube that unblocks the bowel before surgery could lead to fewer cancer patients -- diagnosed as emergencies -- needing a colostomy bag.The Cancer Research UK-funded CReST trial presented at the 2016 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago today (Sunday)* found that less than half (45 per cent) of those who had their bowel unblocked by the tube, which uses body heat to expand, needed a colostomy bag.

Costs associated with different breast cancer chemotherapy regimens can vary significantly, regardless of effectiveness, according to new research from The University of Texas MD Anderson Cancer Center. Understanding cost differences should help guide informed discussions between patients and physicians when considering chemotherapy options.

Sharon Giordano, M.D., chair of Health Services Research and professor of Breast Medical Oncology, will present the findings in a poster discussion session at the 2016 American Society of Clinical Oncology Annual Meeting in Chicago.

HAVING radiotherapy once a day for six and a half weeks or twice a day for three weeks -- when combined with chemotherapy -- is equally good at treating small cell lung cancer that hasn't spread.

These results -- from a Cancer Research UK-funded clinical trial presented at the ASCO cancer conference today (Sunday) -- mean patients and doctors can choose together which treatment suits them best.

DALLAS - June 4, 2016 - A significant proportion of lung cancer patients also have autoimmune disease, which may make them unsuitable for increasingly popular immunotherapy treatments, a team of researchers at UT Southwestern Medical Center's Harold C. Simmons Comprehensive Cancer Center has found.

The UT Southwestern cancer researchers calculated that between 14 to 25 percent of lung cancer patients reviewed also had immune disease, and these individuals were more likely to be female and older, according to the findings reported today in JAMA Oncology.

Pregnant women overestimate the risks of taking over the counter and prescribed medication - according to new research from the University of East Anglia (UEA).

The findings reveal that women choose not to medicate common pregnancy symptoms such as nausea, heartburn and aches and pains.

Most worryingly, mums-to-be are choosing not to take medication for UTIs - which can cause significant complications and harm the foetus if left untreated.

According to a new study published today in the journal Population Development and Review, 61% of citizens within the EU-15 see themselves as European in addition to or in lieu of their national identity in 2013, compared to 58% on average from 1996 to 2004. The largest increases were seen in Germany, Austria, Sweden, and Finland, and surprisingly also in Greece. In contrast the United Kingdom and France saw a decline in European identity, with the UK coming at the very bottom.

ROCHESTER, Minn. -- Pten (short for phosphatase and tensin homolog) is a tumor suppressor that is defective in about 20-25 percent of all patients with cancers. Mayo Clinic researchers now have discovered that Pten safeguards against tumor formation by keeping chromosome numbers intact when a cell splits into two daughter cells. In this study, the last three amino acids of the Pten protein, which are often missing in human cancers, were found to be critical for forming an intact mitotic spindle, a structure required for accurate chromosome segregation.