Body

Charlotte, N.C., June 9, 2016 - A study of emergency department (ED) patients with symptoms of gonorrhea or chlamydia found that three in four patients who were treated with antibiotics actually tested negative for these sexually transmitted diseases (STDs), according to a new study presented at the 43rd Annual Conference of the Association for Professionals in Infection Control and Epidemiology (APIC).

Charlotte, N.C., June 9, 2016 - Can you use the "ick factor" to get healthcare workers to clean their hands more often? Yes, according to a new study being presented on June 11 at the 43rd Annual Conference of the Association for Professionals in Infection Control and Epidemiology (APIC).

Although mankind has been using silk for millennia, many aspects of its properties and molecular structure remain unknown. Now, a new study from the RIKEN Center for Sustainable Resource Science (CSRS) in Japan reveals that amino acid sequences are key determinants of the material properties of silk fibers. The work was performed by CSRS scientists in an international collaboration with Beihang University, Indian Institute of Technology Guwahati and Chulalongkorn University.

In a recent development, scientists at the Tata Institute of Fundamental Research report that damage to DNA can be induced by ultrashort pulses of high intensity laser light. Published in Scientific Reports, these findings have important implications in clinical conditions, especially in reducing collateral damage to tissues surrounding the real target of conventional radiotherapy.

Patients with late-stage, non-small cell lung cancer (NSCLC) who have surgery have better survival rates than those who don't, but fewer of these patients are undergoing surgery, UC Davis researchers have found.

Published today in The Annals of Thoracic Surgery, the study raises an important question: Why aren't more patients evaluated for surgery as part of a comprehensive treatment regimen for the world's deadliest cancer?

People with cancer are often told by their doctors approximately how long they have to live, and how well they will respond to treatments, but what if there were a way to improve the accuracy of doctors' predictions?

Newcastle University scientists have discovered a new essential sequence within bacterial genomes required for DNA replication - the second ever to be discovered and the first for 30 years.

Publishing today in Nature, the Newcastle team describe how they identified the new site and determined the mechanism by which it promotes DNA duplication.

The "DnaA-trio" is described as a core element of bacterial replication origins and represents a significant advance for scientific understanding.

Sean Nygaard and colleagues have developed a new technique that may help to overcome one of the largest hurdles in gene therapy--the ability to generate a large pool of gene-corrected cells that would be effective in repairing or correcting injury and disease. What's more, in their method, the genetically corrected cells can repopulate in vivo. To date, efforts to modify and deliver genetically modified cells to treat various disorders have required the delivery of thousands of cells, many of which don't survive.

Rochester, MN, June 8, 2016 - The risk of life-threatening blood infections by Staphylococcus aureus bacteria is more than doubled in users of systemic glucocorticoids compared with non-users. The risk escalates with increasing dose, according to a new Danish population-based case-control study published in Mayo Clinic Proceedings.

NEW YORK (June 8, 2016) - Scientists from the Center for Radiological Research at Columbia University Medical Center have shown that a narrow wavelength of ultraviolet (UV) light safely killed drug-resistant MRSA bacteria in mice, demonstrating a potentially safe and cost-effective way to reduce surgical site infections, a major public health concern.

Scientists at the Wellcome Trust Sanger Institute and their international collaborators have shown that Acute Myeloid Leukaemia (AML) is not a single disorder, but at least 11 different diseases, and that genetic changes explain differences in survival among young AML patients. Published in the New England Journal of Medicine, the ground-breaking study on the genetics of AML could improve clinical trials and the way patients are diagnosed and treated in the future.

A new study led by investigators at Massachusetts General Hospital (MGH) has identified a mechanism behind the surge in cardiovascular inflammation that takes place after a heart attack. Working with collaborators from the Massachusetts Institute of Technology (MIT), the team also developed a potential strategy for suppressing inflammation within atherosclerotic plaques, the first approach that targets the immune system's contribution to cardiovascular disease. Their work in animal models of heart disease is described in a Science Translational Medicine paper.

A new IVF-based technique is likely to lead to normal pregnancies and reduce the risk that babies born will have mitochondrial disease, according to researchers at the Wellcome Trust Centre for Mitochondrial Disease at Newcastle University.

Published today in the journal Nature, scientists report the first in-depth analysis of human embryos created using a new technique designed to reduce the risk of mothers passing on mitochondrial disease to their children, which is debilitating and often life-limiting.

BIRMINGHAM, Ala. - Jianyi "Jay" Zhang, M.D., Ph.D., brought his biomedical engineering expertise to the University of Alabama at Birmingham to fix hearts.

His dream -- and the dream of other heart experts at major research universities around the world -- is creating new tissue that can replace or protect damaged muscle after a heart attack.

June 8, 2016 - Recovery-oriented systems of care (ROSC) offer a promising approach to improving care for the millions of individuals who have substance use disorders and, very frequently, co-occurring mental health disorders.