DURHAM, N.C. - Women who carry the BRCA1 gene mutation that dramatically increases their risk of breast and ovarian cancers are also at higher risk for a lethal form of uterine cancer, according to a study led by a Duke Cancer Institute researcher.
This newly defined risk - the first to show a conclusive link between the BRCA1 gene mutation and a small but significant chance of developing an aggressive uterine cancer - could become a consideration in weighing treatment options.
Senior citizens with undiagnosed or untreated hearing problems are more likely to suffer from social isolation and cognitive impairment, a UBC study has found.
UBC Okanagan researchers examined the impact of undiagnosed or untreated hearing issues in seniors aged 60 to 69. The study found that for every 10 decibel (roughly the sound of calm breathing) drop in hearing sensitivity, the odds of social isolation increased by 52 per cent.
Researchers have described a new genus and species of cavefish from Mexico - the Oaxaca Cave Sleeper. It has not been collected or seen in more than 20 years and lives in a cave system threatened by damming. Less than 0.5 percent of all fish species are cave-adapted and most of them are endangered because their cave habitats are limited and vulnerable to environmental threats.
DALLAS - June 30, 2016 - Proteins that play key roles in the timing of cell division also moonlight in regulating blood sugar levels, UT Southwestern Medical Center researchers have found.
HOUSTON - (June 30, 2016) - The chemotherapy treatments necessary to treat Acute Myeloid Leukemia (AML) in children can be grueling on the body, and can cause health-related complications during therapy, as well as long down the road after remission. Children receiving chemotherapy for AML receive 4 to 5 intensive chemotherapy courses, and while some children recover quickly from each course, others may take several months or more, which increases their risk for life-threatening infections.
An international group of scientists from US, Canada, Germany and Russia has revealed a substance produced in humans that can suppress the pro-inflammatory activity of macrophages - specific cells of immune system. The substance known as itaconate is released in large quantities by macrophages themselves, but until now its role remained poorly studied. Now scientists have found evidence that itaconate acts as an antioxidant and anti-inflammatory agent. These properties make itaconate promising for the treatment of pathologies caused by excessive inflammation or oxidative stress.
ANN ARBOR, Mich. -- When a woman is diagnosed with the earliest stage of breast cancer, how aggressive should her treatment be? Will the non-invasive cancer become invasive? Or is it a slow-growing variety that will likely never be harmful?
Researchers at the University of Michigan developed a new technology that can identify aggressive forms of ductal carcinoma in situ, or stage 0 breast cancer, from non-aggressive varieties.
The technique combines imaging and mathematics. It's called biomarker ratio imaging microscopy, or BRIM.
June 30, 2016 Los Angeles--In a report released today by the U.S. Department of Health and Human Services (HHS), an Independent Panel formed to review HHS's response to Ebola made several recommendations on how the nation's federal public health system should strengthen its response to major public health threats, both internationally and domestically.
An experimental vaccine against Zika virus developed by Brazilian and US researchers has been tested successfully in trials with mice.
The results were published on June 28, 2016 in Nature and according to the authors suggest a vaccine can be produced for humans in the near future.
Sports fans are about to get a whole new way of experiencing the upcoming Tour de France and select endurance sports at the Rio 2016 Olympics thanks to a start-up out of CSIRO's Data61 group.
This year, spectators through doarama.com will be able to access customised 3D interactive map visualisations of the routes which will be used for the Tour de France (July 2 to 24).
Fans will be able to interact with the maps by controlling how they view the route in a 3D virtual world.
Since the completion of the human genome an important goal has been to elucidate the function of the now known proteins: a new molecular method enables the investigation of the function for thousands of proteins in parallel. Applying this new method, an international team of researchers with leading participation of the Technical University of Munich (TUM) was able to identify hundreds of previously unknown interactions among proteins.
A new analysis of UK workers reveals that certain occupations may increase the risk of bladder cancer.
After analyzing 25 articles, investigators found that the greatest risk of developing bladder cancer occurred in workers within the chemical, rubber, and dye industries. In contrast, the greatest risk of death from bladder cancer was in electrical, chemical, and transport workers. Such deaths were also higher in the North of England, probably reflecting smoking patterns and industrial distributions.
The latest comprehensive analysis of national plans to address climate change after 2020 shows the world will not reach its target of keeping warming to below 2C off pre-industrial levels.
Instead, the globe could suffer a median rise of between 2.6 and 3.1C by 2100 according by the Intended Nationally Determined Contributions (INDCs) submitted in preparation for the 2015 climate talks in Paris.
While it is an improvement from current policy and no-policy scenarios, it still falls short of the 2C target, not to mention the hopeful goal of 1.5C warming.
A new study found that certain factors affect cervical cancer screening among lesbian and bisexual women and transgender men. Some of these factors overlap with the general female population, whereas others are specific to the lesbian, bisexual, or queer identity.
Patients who were screened routinely felt more welcome in the health care setting, while nonroutine screeners reported more discrimination related to their sexual orientation and gender expression. Routine screeners were also more likely to 'out' to their provider.
Messenger RNA (mRNA) is made up of exons and introns, that is, portions of genetic information that are "switched on" and "switched off", respectively. In order to reach maturation and be sent to the cellular "machine" that deals with protein synthesis, the non-coding fragments contained in the mRNA, the introns, need to be removed, whereas the coding sequences, the exons, have to be linked together. In humans, this "snipping and stitching" process, known as splicing, is governed by a huge machinery consisting of proteins and RNA, the spliceosome.