Precise predictions of whether a tumor is likely to spread would help clinicians and patients choose the best course of treatment. But current methods fall short of the precision needed. New research reveals that profiling primary tumor samples using genomic technologies can improve the accuracy of breast cancer survival predictions compared to clinical information alone. The study was published in the journal GENETICS, a publication of the Genetics Society of America.
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Bamboo worms (family Maldanidae) comprise an easily recognizable family of bristle worms (class Polychaeta). Their common name they receive because of their elongated segments, ending with an appendage, which gives them the joint appearance of slender bamboo-shoots. These often fragile marine inhabitants can be found in mud-walled tubes in shelf sediments.
EAST LANSING, Mich. -- A collaborative Michigan State University study involving microbiologists, epidemiologists, animal scientists, veterinarians, graduate students, undergraduates and farmers could lead to better prevention practices to limit dangerous E. coli bacteria transmissions.
Grouping young tennis players according to their physical maturity rather than their chronological age could help us develop future tennis champions, says research by the University of Bath.
Boys and girls can vastly vary in their rates of growth and maturity during adolescence. Those that mature early are taller, quicker, bigger and stronger, giving them a significant advantage over their late maturing peers. This means that later maturing players are often overlooked in the elite tennis selection process.
Clinical practice guidelines can improve the quality of health care. However, the prerequisite for this is their dissemination and application. Although no best practice model for Germany is available, several requirements and measures exist that could promote implementation. For instance, guidelines should be supported by evidence and be locally applicable. In addition, training and reminder systems for users could be helpful. This is the result of the final report published by the German Institute for Quality and Efficiency in Health Care (IQWiG) on 5 July 2016.
July 6, 2016 - Can an increased risk of chronic pain be transmitted from parents to children? Several factors may contribute, including genetics, effects on early development, social learning, and more according to a report in the journal PAIN®, the official publication of the International Association for the Study of Pain (IASP). The journal is published by Wolters Kluwer.
CAMBRIDGE, MA -- Researchers at MIT's research center in Singapore have developed a new microfluidic device that tests the effects of electric fields on cancer cells. They observed that a range of low-intensity, middle-frequency electric fields effectively stopped breast and lung cancer cells from growing and spreading, while having no adverse effect on neighboring healthy cells.
LUGANO, 06 July 2016 - ESMO, the leading European professional organisation for medical oncology, has released new consensus guidelines for the management of metastatic colorectal cancer that reflect an increasingly personalized approach to treatment, as published online today in Annals of Oncology(1).
Imagine an agriculture field. Most are planted with row upon row of tidy cash crops. Now imagine that same field with rows of trees between the rows of crops. This forested field concept is called alley cropping. Alley cropping helps farmers diversify by growing long-term tree crops alongside short-term cash crops like wheat.
"For so long farmers have been taking trees off farmland," said Josh Gamble, agroforestry researcher at the University of Minnesota Twin Cities, "So the idea of putting trees back on is a little bit of a barrier."
JULY 06, 2016, NEW YORK -- Ludwig researchers working in collaboration with colleagues in Australia and the US have shown that fragments of tumor DNA circulating in the blood can be used to gauge the risk of colorectal cancer recurrence and the efficacy of chemotherapy following surgery. The finding, published today in the current issue of the journal Science Translational Medicine, is an important step toward the development of a non-invasive and more effective test for the detection, monitoring and treatment of cancer.
A research team led by Breast Health Fellow Rebecca M. Kwait, MD, at The Breast Health Center at Women & Infants Hospital of Rhode Island, a Care New England hospital, recently presented research indicating that when faced with a decision on the type of surgery to have to remove breast cancer, more women trust their own judgment over the input of their surgeon and even their partner.
- Pelleting, extrusion, and pelleting plus extrusion increased the digestibility of indispensable amino acids.
- Pelleting of low-fiber diets increases digestible energy by 1.9 percent and metabolizable energy by 2.1 percent.
- Pelleting of medium-fiber diets increases digestible energy by 1.9 percent and metabolizable by 2.2 percent.
- Pelleting did not increase digestible energy or metabolizable of high-fiber diets, but extrusion increased digestible energy by 2.0 percent and metabolizable by 2.9 percent
Massachusetts General Hospital (MGH) investigators have discovered the mechanism by which obesity increases inflammation and desmoplasia - an accumulation of connective tissue - in the most common form of pancreatic cancer. In their report published online in Cancer Discovery the researchers describe how interactions among fat cells, immune cells and connective tissue cells in obese individuals stimulate a microenvironment that promotes tumor progression while blocking the response to chemotherapy. They also identify a treatment strategy that may inhibit the process.
Buck researchers boosted the potency of a broccoli-related compound by ten times and identified it as a possible treatment for age-related macular degeneration (AMD), the leading cause of vision loss affecting more than 10 million older Americans.
Cancerous tumors must be fed. Their unregulated growth requires a steady stream of blood flow and nutrients. Thus, one way that researchers have tried to wipe out cancer is to target cells undergoing the metabolic shifts that enable a tumor's rapid growth.