Beriberi in infants is a public health concern with reports in parts of Southeast Asia. Caused by thiamine (B1) deficiency, beriberi generally presents among breastfed infants at three months. A disorder characterized by vomiting, convulsions and signs of heart failure, beriberi can be fatal for an infant unless thiamine is rapidly administered. In Cambodia, beriberi can result because of maternal dietary factors, including significant consumption of polished white rice, which lacks in thiamine, and a lack of consumption of thiamine-rich foods.
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- About 40 percent more people improved their health behaviors as a result of texts
- Texting increased fruit and vegetable consumption and reduced fat consumption
- About 66 million people in India have diabetes
- Simple, cost-effective solution could be used in other low and middle-income countries
The main goal of a tumour cell is, above all, to survive, even at the cost of damaging the health of the organism to which it belongs. To do this, it is equipped with skills that healthy cells do not have, including the ability to continue surviving when glucose levels are very low. This could be one of the reasons why widely-used anti-angiogenic agents often fail to eliminate cancer, no matter how much they starve it by hindering the development of the blood vessels that provide nutrients in general and glucose in particular.
Australian genomics researchers have announced the development of Sequins -- synthetic 'mirror' DNA sequences that reflect the human genome. This intuitive new technology, which can be used to better map and analyse complexity within the genome, is freely available to the academic research community.
Scientists have identified a compound that can kill the parasites responsible for three neglected diseases: Chagas disease, leishmaniasis and sleeping sickness. These diseases affect millions of people in Latin America, Asia and Africa, but there are few effective treatments available.
DURHAM, N.C. -- In the search for new ways to attack recurrent prostate cancer, researchers at Duke Health report that a novel compound appears to have a unique way of blocking testosterone from fueling the tumors in mice.
The potential foundation for a next-generation therapy, called tetraaryl cyclobutane, or CB, is being studied as an option for prostate tumors that have grown resistant to current anti-androgen drugs, notably enzalutamide.
Ever since the prion gene was discovered in 1985, its role and biological impact on the neurons has remained a mystery. "Finally, we can ascribe a clear-cut function to prion proteins and reveal that, combined with particular receptor, they are responsible for the long-term integrity of the nerves," says Professor Adriano Aguzzi from the Neuropathological Institute at the University of Zurich and University Hospital Zurich. The present study therefore clears up a question that researchers have been puzzling over for 30 years, but ultimately went unanswered.
Scientists have identified four new pathogens previously not found in Australian chillies, raising the stakes for the country's quarantine and disease resistance efforts.
The pathogens, all part of the Colletotrichum species, cause a fungal disease called anthracnose, which lowers yield and produces large, sunken black spots on a variety of fruits and vegetables.
While anthracnose already exists in Australia, the discovery of four new pathogens in chillies raises important new questions about how to better protect Australia's horticultural industry.
Researchers identified two types of olfactory receptors in human muscle cells of bronchi. If those receptors are activated by binding an odorant, bronchi dilate and contract - a potential approach for asthma therapy.
This is the conclusion drawn by a team headed by Prof Dr Dr Dr habil Hanns Hatt and Dr Benjamin Kalbe at the Department for Cellphysiology in Bochum. Together with colleagues from various clinics in Bochum, Cologne and Herne, the researchers from Ruhr-Universität Bochum published their report in the journal "Frontiers in Physiology".
Men with very high-risk prostate cancer, who are treated at hospitals with a high proportion of administered radical local treatment (radiotherapy or prostatectomy), only have half of the mortality risk of men who are treated at hospitals with the lowest proportion. This is according to a new study conducted by researchers at Umeå University in Sweden and published in European Urology.
Coatings or paints are materials applied to different surfaces basically for decorative and protective purposes. Yet today the market for these materials is being subjected to increasingly tougher specifications. In addition to being decorative and protective, today's coatings must have additional properties such as, for example, low microorganism-adherence, ease of cleaning or self-repair properties.
For many years, researchers have been trying to understand the origin of the exceptionally long trunks that characterize the body of snakes. This is a mystery in terms of animal development that can shed light on the mechanisms controlling the tissues that form the trunk, including the skeleton and the spinal cord. A research team led by Moisés Mallo from Instituto Gulbenkian de Ciência (IGC, Portugal) now discovered the key factor that regulates trunk development in vertebrates and explains why snakes have such a strikingly different body.
Australian researchers have discovered that a new class of anti-cancer agents may be effective in treating multiple myeloma, an incurable bone marrow cancer.
The research revealed that the majority of myelomas rely on a protein called MCL-1 to stay alive. Potential drugs that inhibit MCL-1, which are in pre-clinical development, may be a promising new treatment for multiple myeloma.
Looking different to your parents can provide species with a way to escape evolutionary dead ends, according to new research from Queen Mary University of London (QMUL).
The work by researchers at the School of Biological and Chemical Sciences looked at polyploid hybrids in the genus Nicotiana, the group that includes tobacco.
Researchers from James Cook University and Charles Darwin University are using the cutting-edge eDNA (environmental DNA) technique to look for the critically endangered largetooth sawfish in remote northern Australia.
eDNA sampling involves collecting a small sample of the water and analysing it for traces of the DNA of a target species. It has been made possible by huge advances in the field of DNA collection and analysis and is considered a revolutionary technology in the natural sciences.