Reston, VA - According to a new report by the Harvey L. Neiman Health Policy Institute, mammography may present an opportunity for the expanded use of bundled payments in radiology.
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Afatinib (trade name: Giotrif) has been approved since April 2016 for the treatment of adults with locally advanced or metastatic non-small cell lung cancer (NSCLC) of squamous histology who have already received chemotherapy. In an early benefit assessment, the German Institute for Quality and Efficiency in Health Care (IQWiG) has now examined whether in these patients this drug offers advantages over the appropriate comparator therapy. According to the findings, an added benefit of afatinib for these patients is not proven.
Dyskeratosis congenita, or DC, is a rare, inherited disease for which there are limited treatment options and no cure. Typically diagnosed in childhood, the disorder causes stem cells to fail, leading to significant problems including bone marrow failure, lung fibrosis, dyskeratosis of the skin and intestinal atrophy and inflammation. Patients are also at heightened risk of several types of cancer.
ANN ARBOR, Mich. -- As scientists learn more about which genetic mutations are driving different types of cancer, they're targeting treatments to small numbers of patients with the potential for big payoffs in improved outcomes.
But even as we learn more about these driver mutations, a new study suggests the science might be leaving racial and ethnic minorities behind.
Leesburg, VA, August 18, 2016-- A team of Boston researchers found that CT attenuation measurements can be used to distinguish untreated osteoblastic (bone-related) metastases from enostoses (benign bone lesions). Based on this conclusion, some biopsies and additional radiologic studies could be avoided, according to a paper published in the August 2016 issue of the American Journal of Roentgenology.
Human papillomavirus (HPV) is one of the most common sexually transmitted infections in the United States and has been identified as a primary cause of cervical cancer in women. Now, an international team of researchers led by the University of Missouri has completed studies on fruit flies with a condition that mimics a form of HPV-induced cancer. The fly models the team developed may help scientists understand the underlying mechanism by which this virus can cause cancer as well as identify potential drug treatments. The study appears in today's issue of PLoS Pathogens.
BOSTON - (August 18, 2016) - Within our bodies, high levels of reactive forms of oxygen can damage proteins and contribute to diabetic complications and many other diseases. But some studies are showing that these reactive oxygen species (ROS) molecules sometimes can aid in maintaining health--findings now boosted by a surprising discovery from Joslin Diabetes Center researchers.
Researchers from the Federal Research and Clinical Centre of Physical-Chemical Medicine, and staff from MIPT's Systems Biology Laboratory, the Research Institute of Phthisiopulmonology and the St. Petersburg Pasteur Institute, conducted a large-scale analysis of the proteins and genomes of mycobacterium tuberculosis strains that are common in Russia and countries of the former Soviet Union and found features that provide a possible explanation for their epidemiological success.
Bottom Line: Parents are more likely to support laws that would make the human papillomavirus vaccine mandatory for school entry if their state offers opt-out provisions, however, the study's lead author cautioned that such opt-out provisions may weaken the effectiveness of the vaccine requirements.
Journal in Which the Study was Published: Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
CHAPEL HILL-Requiring students to get vaccinated against the human papillomavirus, or HPV, to enter school could prevent many cancers linked to the virus, but University of North Carolina at Chapel Hill researchers found that many parents only support such requirements with opt-out provisions that could make the laws less effective.
SEATTLE -- Gendered expectations in marriage are not just bad for women, they are also bad for men, according to a new study by University of Connecticut (UConn) sociologists.
The study, "Relative Income, Psychological Well-Being, and Health: Is Breadwinning Hazardous or Protective?" by Christin Munsch, an assistant professor of sociology at UConn, and graduate students Matthew Rogers and Jessica Yorks, will be presented at the 111th Annual Meeting of the American Sociological Association (ASA).
Genetically analysing lesions in the food pipe could provide an early and accurate test for oesophageal cancer, according to research led by Queen Mary University of London (QMUL), Academic Medical Center in Amsterdam and Arizona State University. The study, published in Nature Communications, shows that some cells that are 'born to be bad' could be identified early on, preventing the need for repeated endoscopies.
Testing for the activity of two genes could pick out women who are at increased risk of dying from their breast cancers, suggests a new study of almost 2,000 patients.
Women whose tumours had a specific pattern of activity in the two genes were three times as likely to die within 10 years as others with a different pattern of activity.
Scientists at The Institute of Cancer Research, London, spotted the pattern of gene activity among breast cancer cells with a particular ability to escape from the glue that normally holds them in place.
Contrary to earlier reports, giving acetaminophen (Tylenol, etc.) for pain and fever does not worsen asthma in young children with the condition, concludes a randomized trial in the August 18 New England Journal of Medicine.
A large screening programme has identified several genes associated with age-related conditions including hearing loss, retinal degeneration and osteoarthritis. The animal study, published in Nature Communications, may lead to studies of the equivalent human gene and help develop screening programmes to identify the risk of developing an age-related condition many years before symptoms appear.