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Geneva, Switzerland, 12 April 2018 - Alectinib provides longer symptom improvement than crizotinib in ALK-positive non-small-cell lung cancer (NSCLC), according to results from the ALEX trial (1) presented at the ELCC 2018 (European Lung Cancer Congress) in Geneva, Switzerland. (2)
PHILADELPHIA - (April 12, 2018) - Wistar researchers have identified a novel therapeutic vulnerability in NRAS mutant melanoma and an effective strategy to address it, using a combination of two clinically relevant inhibitors, according to study results published online in EMBO Molecular Medicine.
Geneva, Switzerland, 12 April 2018 - Investing in the continuity of care for lung cancer patients can bring tremendous benefits in terms of patient satisfaction and quality of life. In Quebec, Canada, this investment has taken the form of a dedicated role on the medical team: The Pivot Nurse in Oncology (PNO). A study presented at ELCC 2018 (European Lung Cancer Congress) in Geneva (1) has produced new evidence of the different ways in which this service improves patients' lives during treatment. (2)
APRIL 11, 2018, NEW YORK - Ludwig Cancer Research released today the full scope of findings to be presented by Ludwig researchers at this year's American Association for Cancer Research (AACR) Annual Meeting in Chicago, Ill., April 14-18, 2018. Research conducted by more than 100 Ludwig scientists will be presented in symposiums, plenaries, town meetings, education sessions and poster sessions.
A new paper has called for an end to the term 'healthy obesity', due to it being misleading and flawed. The focus should instead be on conducting more in-depth research to understand causes and consequences of varying health among people with the same BMI.
The term 'healthy obesity' was first used in the 1980's to describe obese individuals who were apparently healthy -- for example they didn't suffer with hypertension or diabetes.
ANN ARBOR, Mich. - A vaccine may successfully turn off peanut allergy in mice, a new study shows.
Just three monthly doses of a nasal vaccine protected the mice from allergic reactions upon exposure to peanut, according to research from the Mary H. Weiser Food Allergy Center at the University of Michigan.
The study, funded by grants from Food Allergy Research and Education (FARE) and the Department of Defense, was published in the Journal of Allergy and Clinical Immunology.
(PHILADELPHIA) -- The most common type of lung cancer, non-small cell lung cancer (NSCLC), continues to be difficult to treat, with five year survival rates of about 36 percent for stage 3A tumors. Jefferson College of Pharmacy researchers are developing a new treatment approach based on nanotechnology that was recently shown to be effective in mouse models of the disease. The research was published in the journal Molecular Pharmaceutics.
The risk of dementia, including Alzheimer's, was significantly higher in people who had experienced a traumatic brain injury (TBI) than with people who had no history of TBI, according to one of the largest studies to date on that association.
Findings from a review of nearly 2.8 million patient cases in Denmark were published April 10 in The Lancet Psychiatry.
The overall risk of dementia in individuals with a history of TBI was 24 percent higher than those without a history of TBI, after accounting for other risk factors for the disease.
PHILADELPHIA - The longer a patient with a positive screening result waits for diagnostic testing, the worse their cancer outcomes may become, according to a literature review of breast, cervical, colorectal, and lung studies in the journal CA led by researchers at the Perelman School of Medicine at the University of Pennsylvania.
"Most people with a mild head injury take off work for a week and then forget about it, but some end up with long-term ailments like headaches," says Lena Hoem Nordhaug, a PhD candidate in neuromedicine at the Norwegian University of Science and Technology (NTNU).
She recently published her findings in the The Journal of Headache and Pain.
Headaches became worse
The study shows that people who were hospitalized with a mild head injury had twice as high a risk of developing headaches, or exacerbating pre-existing headaches, than the rest of the population.
A new study by Althea Campuzano, Ph.D. a student at The University of Texas at San Antonio, and Floyd Wormley, Jr., Professor of Biology and Senior Associate Dean for Research and Graduate Studies, sheds light on little-known fungal infections caused by the fungus Cryptococcus. There are currently no vaccines available for any fungal infection, which can be extremely deadly to patients under treatment for diseases like HIV, AIDS and cancer. Campuzano and Wormley suggest that more research is needed to develop an effective solution to these infections.
Heart failure is a leading cause of maternal morbidity and death in the U.S. -- with the rate of pregnancy-related deaths more than doubling between 1987 and 2011. Even so, much about heart failure-related hospitalizations before, during and after delivery is unknown.
A study from the University of Illinois at Chicago has found that women are at the highest risk for heart failure within the six weeks after delivery, known as the postpartum period.
In a recently published study in the Annals of Family Medicine, Aimee English, MD, et al, describe a cluster-randomized trial evaluating the differential impact on cardiovascular disease care of engaging patients and communities in practice transformation in addition to standard practice facilitation support.
Practice facilitation is a promising approach to helping medical practices implement quality improvements. In a recently published study in the Annals of Family Medicine, Megan McHugh, et al, aimed to describe practice facilitators’ and practice leaders’ perspectives on implementation of a practice facilitator-supported quality improvement program and describe where their perspectives aligned and diverged.
Taking part in a hot chilli pepper eating contest might have some unexpected consequences, highlight doctors in the journal BMJ Case Reports.
Their warning comes after a young man ended up in emergency care with excruciatingly painful episodic headaches after eating a 'Carolina Reaper,' the world's hottest chilli pepper.
His symptoms started immediately after he had eaten the chilli, with dry heaves. But he then developed severe neck pain and crushingly painful headaches, each of which lasted just a few seconds, over the next several days.