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Bottom Line: An early study suggests it may be feasible to use human aortic grafts preserved by freezing to rebuild windpipe and airway sections removed because of disease.
Why The Research Is Interesting: Airway replacement could potentially benefit many patients with lung cancer and be an option for patients with end-stage tracheobronchial disease.
ATS 2018, San Diego, CA - A long-term study of the health of Canadian children has found that exposure to ozone (O3), a common air pollutant, at birth was associated with an 82 percent increased risk of developing asthma by age three. The study, which was a 10-year follow-up to the 2006 Toronto Child Health Evaluation Questionnaire (T-CHEQ), was presented at the 2018 American Thoracic Society International Conference.
Inpatient opioid use and insufficient weaning pre-discharge may increase outpatient opioid prescript
According to the University of Pittsburgh School of Medicine scientists who conducted the study, theirs is the first large-scale evaluation of the impact of in-hospital opioid prescribing on post-discharge opioid use.
PORTLAND, OR - Twenty five years after it opened for enrollment, the landmark Prostate Cancer Prevention Trial has delivered a final verdict. Finasteride, a common hormone-blocking drug, reduces mens' risk of getting prostate cancer without increasing their risk of dying from the disease. Initial study findings suggested there may be a link between use of the drug and a more lethal form of prostate cancer, but long-term follow-up shows that is not true.
East Hanover, NJ. May 18, 2018. Stroke researchers have confirmed that the presence of frontal cortical lesions moderated response to prism adaptation treatment after right-brain stroke. Their findings are detailed in "Frontal lesions predict response to prism adaptation treatment in spatial neglect: A randomised controlled study" (doi: 10.1080/09602011.2018.1448287), which was published online ahead of print on March 20, 2018 by Neuropsychological Rehabilitation. The authors are Kelly M.
HOUSTON - (May 18, 2018) - A study led by a neurologist from McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth) showed that a computed tomography (CT scan) could be sufficient for determining thrombectomy treatment in stroke.
The late-breaking results were presented by Amrou Sarraj, M.D., today at the European Stroke Organization Conference in Sweden.
CORVALLIS, Ore. - Researchers at Oregon State University have developed a computer program that represents a key step toward better understanding the connections between mutant genetic material and disease.
Known as bpRNA, the software is a big-data annotation tool for secondary structures in ribonucleic acids.
In "Does Armodafinil Improve Driving Task Performance and Weight Loss in Sleep Apnea? A Randomized Trial," Nathaniel Marshall, PhD, and his colleagues at the Woolcock Institute for Medical Research, University of Sydney, report on their study of armodafinil, which has been approved by the U.S. Food and Drug Administration to treat excessive daytime sleepiness due to OSA, narcolepsy and other conditions.
PHILADELPHIA - An antibody used to treat the skin disease psoriasis and other chronic autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease has no effect on aortic inflammation - a key marker of future risk of major cardiovascular events - unlike other antibodies that target different aspects of the immune system.
BOSTON -- Researchers from Hebrew SeniorLife's Institute for Aging Research, and Boston Medical Center have reported that one-third of people 40-59 years have image-based evidence of moderate to severe degenerative disc disease and more than half had moderate to severe spinal osteoarthritis. Beyond that, the prevalence of disc height narrowing and joint osteoarthritis increased 2 to 4 fold in those aged 60-69 and 70-89 respectively. Furthermore, scientists observed that progression of these conditions occurred 40 - 70% more frequently in women than men.
DENVER/May 17, 2018 - Morris Animal Foundation-funded researchers from the University of Sydney have found a previously undiscovered hepadnavirus in an immunocompromised cat, and subsequently in banked feline blood samples. The research team published their results today in the prestigious journal Viruses.
PHILADELPHIA - A targeted therapy that has shown its power in fighting ovarian cancer in women including those with BRCA1 and BRCA2 mutations may also help patients with aggressive pancreatic cancer who harbor these mutations and have few or no other treatment options. An international team of researchers led by the Perelman School of Medicine and the Basser Center for BRCA at the University of Pennsylvania reported their findings this week in JCO Precision Oncology.
A new study shows that a kind of E. coli most associated with "travelers' diarrhea" and children in underdeveloped areas of the world causes more severe disease in people with blood type A.
Ann Arbor, May 17, 2018 - The US mental health system faces considerable challenges in delivering behavioral healthcare to populations in need. In a special supplement to the American Journal of Preventive Medicine, experts focus on the key issue of behavioral health human resources for which substantial investment is needed to effect change.
An automated system for identifying patients at risk for complications associated with the use of mechanical ventilators provided significantly more accurate results than did traditional surveillance methods, which rely on manual recording and interpretation of individual patient data.