Body

Preliminary results of a recent study show that teen girls reported a higher degree of interference of daytime sleepiness on multiple aspects of their school and personal activities than boys.

The study examined whether teen boys and girls report similar negative impact of sleep disturbances on their daytime functioning.

Hip replacements relieve pain and restore mobility for hundreds of thousands of patients in the United States each year, but about 40,000 of the more than 280,000 of these procedures performed annually in the U.S. are to replace failed previous hip replacements, at a direct cost of more than $1 billion. One main cause of the need to perform a second hip replacement surgery (known as a revision surgery) is the destruction of bone tissue around the replacement joint, a condition called osteolysis, which may cause the joint to loosen.

Drugs used to treat rheumatoid arthritis may impact mental health by improving pain and stiffness and by targeting inflammatory processes common to arthritis and depression; however, a recent review of published studies demonstrates that relying on rheumatoid arthritis therapies alone may not meaningfully improve patients' mental health.

Buprenorphine (BUP) is approved for the treatment of opioid addiction. The current dosing regimen of BUP in pregnant women is based on recommendations designed for non-pregnant adults, but physiological changes during pregnancy may alter BUP exposure and efficacy. As described in a British Journal of Clinical Pharmacology study, researchers have developed a physiologically based pharmacokinetic model that predicts changes in BUP exposure at different stages of pregnancy.

Autologous fat transfer, also known as "lipofilling", is a minimally invasive procedure in which the plastic surgeon uses the patient's own fat obtained by liposuction to perform breast reconstruction.

Two drugs that are commonly used off-label in the treatment of male infertility are clomiphene citrate (CC) and anastrozole (AZ); however, data are lacking on the use of combination CC+AZ therapy. A new BJU International study found that combination CC+AZ therapy is safe and effective for patients with elevated estradiol or a low testosterone/estradiol ratio.

Exposure to tobacco smoke prenatally and postnatally was associated with hearing impairment in a Paediatric and Perinatal Epidemiology study of young children in Japan.

Washington, DC - June 5, 2018 - Dogs are a potential reservoir for a future influenza pandemic, according to a study published in the journal mBio. The study demonstrated that influenza virus can jump from pigs into canines and that influenza is becoming increasingly diverse in canines.

The modelled data on overall survival of the statistical evaluation of the impact of crossover on the ADMYRE study were presented.

Of the 84 patients treated in the comparator arm (dexamethasone as a single agent), 44% received the combination with plitidepsin after progression.

After analyzing the impact of crossover, the registered overall survival with plitidepsin was 11.6 months against the 6.4 months of dexamethasone alone.

Researchers have shed light on how taking aspirin can help to stave off bowel cancer.

Experts found that the painkiller blocks a key process linked to tumour formation.

Regular use of aspirin is known to reduce a person's risk of developing colon cancer but the drug's tumour fighting properties have not been well understood.

Researchers at the University of Edinburgh focused on a structure found inside cells called the nucleolus.

The blood vessels of middle-aged men and women adapt differently to regular exercise according to new research being presented today at the British Cardiovascular Society conference in Manchester.

Researchers at Loughborough University examined the effects of regular exercise training on the blood vessels of 12 men and post-menopausal women. Blood pressure and arterial stiffness were assessed before and one hour after a brisk walk.

HOUSTON - Clinical trials show that an immune checkpoint inhibitor shrinks the tumors of nearly half of patients with an incurable, advanced form of a common skin cancer, an international team led by a researcher at The University of Texas MD Anderson Cancer Center reports in the New England Journal of Medicine.

The newer high-sensitivity troponin test discovers smaller amounts of heart-specific proteins, troponins, than the older troponin test and thus identifies more myocardial infarction patients than before. A new study from Karolinska Institutet in Sweden published in The Journal of the American College of Cardiology now reports that the risk of a future heart attack is lower in patients diagnosed with the new test.

MAYWOOD, IL - A major international study has found that 2.6 percent of infants and children hospitalized for stroke die in the hospital.

Loyola Medicine neurologist José Biller, MD, a nationally known expert on strokes in children, is among the co-authors of the study, published in the journal Pediatrics. First author is Lauren A. Beslow, MD, of the Children's Hospital of Philadelphia.

In a new study, researchers at Uppsala University and other institutions have identified genetic material from the recently identified Alkhurma hemorrhagic fever virus in the tick species Hyalomma rufipes. The discovery was made after thousands of ticks were collected from migratory birds captured in the Mediterranean basin. The results indicate that birds could contribute to spreading the virus to new geographical areas.