Body
Scientists find new drugs compound for treating cancer
Cancer is less likely to become resistant to the compound than standard chemotherapy
The compound could be particularly effective against ovarian cancer
Scientists from the University of Sheffield have discovered a compound that could be more effective in treating certain cancers than standard chemotherapy.
PITTSBURGH-- Physicians will be able to predict which of their patients with severe asthma are likely to benefit from treatment with systemic corticosteroids -- and which might only suffer their side effects -- with help from a dozen clinical variables researchers have identified using machine learning techniques.
PHILADELPHIA - Specialized lung cells appear in the developing fetus much earlier than scientists previously thought. A new animal study published this week in the Proceedings of the National Academy of Sciences reports how cells that become alveoli, the tiny compartments in which gas exchange occurs in the lung, begin their specialized roles very early in prenatal life.
Melanoma patients with a history of smoking cigarettes are 40 per cent less likely to survive their skin cancer than people who have never smoked, according to a new report funded by Cancer Research UK.
The study of more than 700 melanoma patients mainly from the north of England - and published today in Cancer Research - provides evidence to suggest that smoking may blight the immune response against melanoma and reduce survival.
Researchers at The University of Texas MD Anderson Cancer Center have discovered that a combination of immune checkpoint blockade and targeted therapies that block normal DNA damage repair (DDR) achieved significant tumor regression in mouse models of small cell lung cancer (SCLC), suggesting a promising new approach for treating patients with this aggressive cancer.
Physicists at McMaster University have for the first time identified a simple mechanism used by potentially deadly bacteria to fend off antibiotics, a discovery which is providing new insights into how germs adapt and behave at a level of detail never seen before.
The findings, published today in the journal Nature Communications Biology, could have implications in the global battle against antibiotic resistance, enabling the design of better, more effective drugs to fight infection.
In the current issue of Cardiovascular Innovations and Applications (Special Issue on Stable Ischemic Heart Disease, Volume 3, Number 3, 2019, pp. 269-278(10); DOI https://doi.org/10.15212/CVIA.2017.0071, Radmila Lyubarova, Joshua Schulman-Marcus and William E. Boden from the Division of Cardiology, Department of Medicine, Albany Medical Center, Albany, NY, USA and VA New England Healthcare System, Boston, MA, USA consider contemporary management of patients with stable ischemic heart disease.
In the current issue of Cardiovascular Innovations and Applications (Special Issue on Stable Ischemic Heart Disease, Volume 3, Number 3, 2019, pp. 279-283(5); DOI: https://doi.org/10.15212/CVIA.2017.0074 C. Richard Conti from the University of Florida Medical School, Gainesville, FL, USA considers epidemiology, pathophysiology, and therapeutic targets in stable ischemic heart disease.
In the current issue of Cardiovascular Innovations and Applications (Special Issue on Stable Ischemic Heart Disease, Volume 3, Number 3, 2019, pp. 285-290(6); DOI: https://doi.org/10.15212/CVIA.2017.0073 Cody Schwartz and David Winchester from the Malcom Randall VAMC, Gainesville, FL, USA consider diabetes mellitus and stable ischemic heart disease.
BOSTON - A combination of two drugs - one of them an immunotherapy agent - could become a new standard, first-line treatment for patients with metastatic kidney cancer, says an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial.
The promises of quantum computing are abundant: for years we've heard how it will break cryptography, make drug discovery a cinch and speed up database search. Researchers around the world have successfully made quantum computers with dozens of quantum bits, but in order to deliver on the promises, they'll need many more.
Feb. 15, 2019--Adults with obstructive sleep apnea (OSA) who experience excessive sleepiness while awake appear to be at far greater risk for cardiovascular diseases than those without excessive daytime sleepiness, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.
LOUISVILLE, Ky. - A research team at the University of Louisville has discovered that an immune checkpoint molecule they developed for cancer immunotherapy, also protects against future development of multiple types of cancer when administered by itself.
PHILADELPHIA - Offering compensation can be an important tactic to attract potential participants for enrollment in research studies, but it might come at a cost. A new study conducted by researchers in the Perelman School of Medicine at the University of Pennsylvania found that up to 23 percent of respondents lied about their eligibility to participate in a survey when offered payment, even small amounts.
Survival after a diagnosis of heart failure in the United Kingdom has shown only modest improvement in the 21st century and lags behind other serious conditions, such as cancer, finds a large study published by The BMJ today.
The findings also show that survival is worse for people requiring admission to hospital around the time of diagnosis, and for those in the most deprived groups.