Body

Current efforts to tackle antibiotic resistance are "not nearly radical enough", a leading scientist says.

Dr Ben Raymond, of the University of Exeter, says relying too heavily on reducing antibiotic use and discovering new drugs could lead to "disaster".

In a new study, he proposes five rules for "sustainable use". These include acting to protect new drugs before resistance becomes a problem, using more diverse antimicrobials to reduce long-term use of single drugs, and using data to design management plans for particular superbugs.

Radiation therapy against cancer can increase the risk of cardiovascular disease much later in life, as the radiation causes chronic inflammation of the exposed blood vessels. In a new study published in the European Heart Journal, researchers from Karolinska Institutet in Sweden have shown that these inflammations can be treated with IL-1 inhibitors.

Inequalities in life expectancy by income in Norway were substantial, and increased between 2005 and 2015, according to a study from the Norwegian Institute of Public Health in collaboration with the Institute For Health Metrics And Evaluation (IHME). Although considerable differences in life expectancy by income levels were found in both Norway and the USA, the shape of the association differed.

The differences in life expectancy between the one per cent richest and one per cent poorest in Norway were 14 years for men and 8 years for women.

Giving a single dose of preventative antibiotics to all women after childbirth involving forceps or vacuum extraction could prevent almost half of maternal infections including sepsis--equivalent to over 7,000 maternal infections every year in the UK, and around 5,000 in the USA [1].

Although surgically induced abortion is a low-risk procedure, women whose physician infrequently performs it have almost twice the risk of severe complications, found new research published in CMAJ (Canadian Medical Association Journal).

"Five things to know about ... melanoma" in CMAJ (Canadian Medical Association Journal) provides a brief overview of this malignant skin cancer for physicians and patients.

Sun exposure is an important factor in the development of melanoma, so it often appears on the face, neck, arms and torso, where sun exposure is common.

Melanoma can also occur on areas with minimal sun exposure, such as palms and soles of the feet.

Las Cruces, NM -- Researchers at the Burrell College of Osteopathic Medicine (BCOM) have found that cancer patients in New Mexico have lower chances of survival when compared to the rest of the nation.

The research was presented by third-year medical student Zac Taylor at the annual meeting of the Arizona Osteopathic Medical Association (AOMA). It was awarded first place among all poster presentations.

Men who delay starting a family have a ticking "biological clock" -- just like women -- that may affect the health of their partners and children, according to Rutgers researchers.

The study, which reviewed 40 years of research on the effect of parental age on fertility, pregnancy and the health of children, was published in the journal Maturitas.

Lisbon, Portugal - 12 May 2019: Artificial intelligence (AI) could prevent unnecessary diagnostic tests in patients with stable chest pain, according to research presented today at ICNC 2019.1 A decision support system saved one hour of testing per patient.

The International Conference on Nuclear Cardiology and Cardiac CT (ICNC) is co-organised by the American Society of Nuclear Cardiology (ASNC), the European Association of Cardiovascular Imaging (EACVI) of the European Society of Cardiology (ESC), and the European Association of Nuclear Medicine (EANM).

DALLAS - May 10, 2019 - A UT Southwestern study suggests why urinary tract infections (UTIs) have such a high recurrence rate in postmenopausal women - several species of bacteria can invade the bladder walls.

UTI treatment is the most common reason for antibiotic prescriptions in older adults. Because of the prevalence of UTIs, the societal impact is high and treatment costs billions of dollars annually.

Compared to patients who see their primary care doctor earlier in the day, cancer screening rates decline significantly as the day goes on, according to a new study from researchers in the Perelman School of Medicine and the Wharton School both of the University of Pennsylvania. The researchers, whose findings were published today in JAMA Network Open, believe these rates of decline may be in part due to "decision fatigue" -- which results from the cumulative burden of screening discussions earlier in the day -- and doctors falling behind in their busy schedules.

Bottom Line: This study of nearly 134,000 patients admitted to intensive care units in France examined the association of age with risk of death in the hospital and then three months and three years after discharge.

Authors: Matthieu Legrand, M.D., Ph.D., L'Assistance Publique-Hopitaux de Paris, France, and coauthors

(doi:10.1001/jamanetworkopen.2019.3215)

WINSTON-SALEM, N.C. - May 10, 2019 - A diet proven to have beneficial effects on high blood pressure also may reduce the risk of heart failure in people under age 75, according to a study led by researchers at Wake Forest School of Medicine, part of Wake Forest Baptist Health.

The observational study of more than 4,500 people showed that those individuals under 75 who most closely adhered to the DASH (Dietary Approaches to Stop Hypertension) diet had a significantly lower risk of developing heart failure than those whose eating habits were least in keeping with the diet.

Trials with people with newly-diagnosed colorectal and non-small cell lung cancer suggest that whole body MRI could reduce the time it takes to diagnose the stage of cancers. The results are from two prospective trials with nearly 500 patients across 16 UK hospitals, published in The Lancet Gastroenterology & Hepatology and The Lancet Respiratory Medicine journals.

In a prospective study of 18,481 pregnant women in China who had never given birth before, obesity in early pregnancy was linked to higher risks of spontaneous abortion, preterm birth, and large birth weight in newborns.

In the Obesity study, being underweight during pregnancy was linked to higher risks for early neonatal deaths, as well as low birth weight.

The findings point to the importance of an appropriate weight before and during pregnancy.