Body
CRISPR-Cas9: First in vivo proof-of-concept in Steinert's myotonic dystrophy, a neuromuscular disease
The benefits of living in a walkable neighbourhood could be diminished by increased exposure to traffic-related air pollution, suggests a study led by St. Michael's Hospital and ICES, a non-profit research institute that uses population-based health information to produce knowledge on a broad range of health care issues.
A new study soon to appear in the Journal of Public Health suggests that air pollution and living in apartment buildings may be associated with an increased risk for dangerous conditions like heart disease, stroke, and type 2 diabetes.
A Finnish study demonstrates that as little as half an hour of light exercise per week effectively protects against subarachnoid haemorrhage, the most lethal disorder of the cerebral circulation.
NEW YORK, June 25, 2019 - In the 1860s, French physician Paul Broca published his findings that the brain's speech production center was located in the left hemisphere. Though scientists have largely accepted since then that the left half of the brain dominates language processing, the reasons behind this lateralization have remained unclear.
People with chronic diseases like arthritis, diabetes and heart disease may one day forego the daily regimen of pills and, instead, receive a scheduled dosage of medication through a grape-sized implant that is remotely controlled.
Worldwide, about 44 million people are living with Alzheimer's disease (AD) or a related form of dementia. Although 82 percent of seniors in the United States say it's important to have their thinking or memory checked, only 16 percent say they receive regular cognitive assessments.
ANN ARBOR, Mich. - Having diabetes is a risk factor for many other health conditions, including stroke.
"Every 40 seconds an American has a stroke," says Frederick Korley, M.D., Ph.D., an assistant professor of emergency medicine at Michigan Medicine. "To be successful at preventing strokes from occurring, we first need to accurately identify those who are likely to have a stroke so we can target stroke prevention therapies to the correct at-risk people."
A new way of detecting liver disease decades before it can become fatal has been developed by a team of scientists at the University of Dundee and NHS Tayside.
It comes as clinicians warn of a `ticking time bomb' of alcohol-related and obesity-related liver diseases.
Liver disease, which is notoriously asymptomatic, has become the second most common cause of death in under 65 year-olds in the UK. Unlike other common causes of death which have begun to decline in recent years, the age-standardised mortality rates for liver disease have risen by nearly 600% since the 1970s.
Washington, DC - June 24, 2019 - A team of investigators has developed a cancer vaccine technology using live, attenuated pathogens as vectors. A feature of the vaccine causes these bacteria to self-destruct once they've done their job, making it safe for use in humans. The research is published in Infection and Immunity, a journal of the American Society for Microbiology.
(BOSTON) - The human microbiome, the vast collection of microbes that colonize the surfaces lining many of our organs and our skin - is a critical pillar sustaining our general health. At any one time, 500 to 1,000 different species of bacteria inhabit us, which together contain far more genes than our human genome. Researchers have also come to realize that no two individuals share the same microbiome, and that an individual's microbiome composition can change with diet, lifestyle, treatment with antibiotics and other drugs, and other factors.
Scientists investigating heart failure have been limited to studying diseased heart tissue in the lab -- understandably, as people don't tend to pluck out a healthy heart for the sake of research. But now, scientists with access to unusable, yet still healthy, donor hearts have been able to investigate the genomic pillars behind the transition from healthy hearts to heart failure.
In doing so, researchers at the Stanford University School of Medicine and their collaborators have created one of the first maps to reveal gene activity and connectivity as the heart shuts down.
Immunotherapies have revolutionized the care of many cancers, teaching the body's own immune cells to recognize and attack tumor cells. Leading the way are drugs known as checkpoint inhibitors, which block a kind of "white flag" that tumors wave as a peace signal to T cells that would very much like to kill them. Really, this white flag is a protein called PD-L1 -- many tumors coat themselves in it. When PD-L1 on the surface of a cancer cell sees its partner, PD1, on T cells, these T cells are tricked into letting the cancer cell live.
BOSTON -- (June 24, 2019) -- New research has identified a type of bacteria found in the microbiomes of elite athletes that contributes to improved capacity for exercise. These bacteria, members of the genus Veillonella, are not found in the guts of sedentary people.
New Haven, Conn. -- Use of 3-D mammography, an advanced form of breast cancer screening, has risen rapidly in recent years, according to Yale researchers in a new study. But adoption of the technology varies widely, reflecting emerging disparities in care, they said.
The study was published in the journal JAMA Internal Medicine.