Body
A new study from Washington University School of Medicine in St. Louis supports evidence that children with mild asthma can effectively manage the condition by using their two inhalers -- one a steroid and the other a bronchodilator -- when symptoms occur. This is in contrast to the traditional method of using the steroid daily, regardless of symptoms, and the bronchodilator when symptoms occur. The as-needed use of both inhalers is just as effective for mild asthma as the traditional protocol, according to the investigators.
When a child suffers a head trauma, medical professionals are in high gear to prevent further damage to a developing brain. Measuring and regulating the child's level of carbon dioxide is critical to ensuring the brain is getting enough blood oxygen to prevent a secondary brain injury. High carbon dioxide can increase intracranial pressure, while a low level is associated with poor brain circulation.
New research published this week in JAMA Oncology has found a lack of racial and ethnic diversity in clinical trials for cancer drugs.
The study--conducted by researchers from UBC, the University of Texas MD Anderson Cancer Center, the Fred Hutchinson Cancer Center in Seattle and Baylor University in Texas--raises concerns about the effectiveness of cancer drugs in some patients, especially since genetic differences may affect how well a patient responds to a drug.
WASHINGTON -- Researchers have developed a new self-calibrating endoscope that produces 3D images of objects smaller than a single cell. Without a lens or any optical, electrical or mechanical components, the tip of the endoscope measures just 200 microns across, about the width of a few human hairs twisted together.
A study from Vanderbilt-Ingram Cancer Center and the Department of Veterans Affairs led by Anna Vilgelm, MD, PhD, and Ann Richmond, PhD, has identified a possible second-line treatment for melanoma patients.
Studying mutant worms has led to the discovery of a receptor that reduces sensitivity to opioid side effects in these organisms. The work implicates the understudied GPR139 receptor in the toxic effect of these painkillers; the authors say GPR139 could be a useful target for increasing opioid safety. Despite side effects like addiction and dependency, opioids such as morphine and fentanyl remain the standard of care for pain relief. These drugs target the mu opioid peptide receptor (MOR).
In the current issue of Cardiovascular Innovations and Applications volume 4, issue 2, pp. 125-134; DOI https://doi.org/10.15212/CVIA.2019.0013, Xiaoyu Zheng, Qingyao Liao, Yue Wang, Hua Li, Xiaodong Wang, Yaohui Wang, Wentao Wu, Junlin Wang, Ling Xiao, and Jing Huang.
In the current issue of Cardiovascular Innovations and Applications volume 4, issue 2, pp. 135-141; DOI https://doi.org/10.15212/CVIA.2019.0015, Ömer Şatıroğlu, Murtaza Emre Durakoğlugil, Hüseyin Avni Uydu, Hakan Duman, Mustafa Çetin, Yüksel Çiçek, and Turan Erdoğan.
Patients who meet an addiction medicine consult team while they're in the hospital are twice as likely to participate in treatment for substance use disorder after they go home, according to new research.
The study, published today in the Journal of General Internal Medicine, measured one key outcome for patients who participated in a first-of-its-kind addiction intervention program started by Oregon Health & Science University in 2015.
A breakthrough in monkey malaria research by two University of Otago scientists could help scientists diagnose and treat a relapsing form of human malaria.
Malaria is a mosquito-borne infectious disease that affects humans and other animals with more than 200 million cases annually, particularly in Asia, the Pacific and South America. Symptoms include fever, tiredness, vomiting and headaches and in severe cases it can cause seizures, coma or death.
Women with severe sleep apnea appear to be at an elevated risk of getting cancer, a study shows. No causal relationship is demonstrated, but the link between nocturnal hypoxia in women and higher cancer risk is still clear.
"It's reasonable to assume that sleep apnea is a risk factor for cancer, or that both conditions have common risk factors, such as overweight. On the other hand, it is less likely that cancer leads to sleep apnea," notes Ludger Grote, Adjunct Professor and chief physician in sleep medicine, and the last author of the current study.
The first large-scale review into the health outcomes of people living with HIV has found that this group has an increased risk of contracting specific diseases and illnesses, some of which are more commonly associated with ageing.
The umbrella review, led by academics from Anglia Ruskin University (ARU) in Cambridge and the Medical University of Vienna, combined data from 20 separate observational studies and examined 55 different illnesses.
A new Pharmacology Research & Perspectives study found no harm to newborns from opioid maintenance treatment (OMT) during pregnancy compared with no treatment.
BOSTON - Pancreatic cancer is one of the deadliest cancers with limited treatment options. It typically comes with an especially poor prognosis due to its lack of symptoms until advanced stages and its ability to resist many anticancer therapies. Identifying genes involved in its development may lead to earlier diagnoses and improved treatments.
In the current issue of Cardiovascular Innovations and Applications volume 4, issue 2, pp. 85-98 ; DOI https://doi.org/10.15212/CVIA.2017.0060, Jayasheel O. Eshcol and Adnan K. Chhatriwalla from Saint Luke's Hospital Mid America Heart Institute, and University of Missouri-Kansas City, School of Medicine, Kansas City, MO, USA consider selective coronary angiography following cardiac arrest.