Body

Blacksburg, Va. – Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have compiled a series of guidelines that should help researchers in their efforts to design, develop and manage next-generation databases of biological parts. The stakes are high: the concept of biological parts is essential if methods developed in other fields of engineering are to be applied to biology. If successful, this approach will result in significant productivity gains for the biotechnology industry.

New evidence suggests that a booster vaccination against H5N1 avian influenza given years after initial vaccination with a different strain may prove useful in controlling a potential future pandemic. The study is published in the August 1 issue of The Journal of Infectious Diseases, now available online.

Multidetector CT using virtual gastroscopy and post contrast enhanced multiplanar reformation images can be useful in differentiating between malignant and benign gastric ulcers, according to a recent study conducted by researchers from Kaohsiung Medical University Hospital in Kaohsiung, Taiwan.

Endangered black-footed ferrets, like children, aren't exactly lining up to be stuck with a vaccine, but in an effort to help control an extensive outbreak of plague in South Dakota, some of the ferrets are getting dosed with a vaccine given by biologists.

Troy, N.Y. ? Growing evidence indicates that exposure to irregular patterns of light and darkness can cause the human circadian system to fall out of synchrony with the 24-hour solar day, negatively affecting human health — but scientists have been unable to effectively study the relationship between circadian disruptions and human maladies.

A study by researchers in Rensselaer Polytechnic Institute's Lighting Research Center (LRC) provides a new framework for studying the effects of circadian disruption on breast cancer, obesity, sleep disorders, and other health problems.

AMARILLO ? Dr. Don Henne isn't wasting his degree when he's standing by the deep fryer waiting for potato slices to turn brown. He's conducting research that will help the potato industry and consumers.

Henne, an assistant research scientist in the Texas AgriLife Research plant pathology program in Amarillo, is one of many who are trying to find answers about zebra chip. Zebra chip is the latest disease to plague the potato industry, especially those in the chipping business.

This press release is available in French.

Montreal, 16 July 2008 - Some people may be naturally resistant to infection with HIV, the virus that causes AIDS. The results of a study conducted by Dr. Nicole Bernard of the Research Institute of the McGill University Health Centre (MUHC) bring us closer to a genetic explanation. Her study findings were published on July 16 in the journal AIDS.

ORLANDO (July 16, 2008)—Are feelings of depression overwhelming you? Is your self-esteem an issue? Having problems advancing in life or your career? Maybe you feel nervous or self conscious in social settings? Do you avoid social settings all together? Check your smile; tooth loss could be the culprit and you're not alone. Nearly 20 million teeth are extracted each year leaving scores of people to deal with the psychological affects of a less than perfect smile. However, during the Academy of General Dentistry's (AGD) 56th Annual Meeting & Exhibits in Orlando, Fla., July 16-20, H.

While some states are taking adequate steps to address the cost of retiree health-care benefits, others – including New Jersey, New York, California and North Carolina – are facing tens of billions of dollars in so-called "unfunded liabilities." The myths and realities of this potential crisis are laid out in a new issue brief written by Dr. Robert Clark, a professor of economics and of management, innovation and entrepreneurship at North Carolina State University, and released by the Center for State and Local Government Excellence.

PROVIDENCE, R.I. – Researchers at Rhode Island Hospital have identified two potential molecular markers that may predict outcomes for patients with stomach cancer, one of the most common and fatal cancers worldwide.

According to the study, published in the July 1 issue of Clinical Cancer Research, patients who had poor outcomes following surgery for stomach cancer also had extremely low amounts of two proteins, known as gastrokine 1 and 2 (GKN1 and GKN2), which are produced by normal stomach cells.

Scientists at Georgia Tech have developed a potential new treatment against cancer that attaches magnetic nanoparticles to cancer cells, allowing them to be captured and carried out of the body. The treatment, which has been tested in the laboratory and will now be looked at in survival studies, is detailed online in the Journal of the American Chemical Society.

PHILADELPHIA – Researchers have determined a novel mechanism through which organ transplantation often leads to cancer, and their findings suggest that targeted therapies may reduce or prevent that risk.

In the July 15, 2008, issue of Cancer Research, researchers at Harvard Medical School found in animal and laboratory experiments that the anti-rejection, immunosuppressive drug cyclosporine ramps up expression of vascular endothelial growth factor (VEGF), which signals the growth of new blood vessels that can feed tumors.

A study by researchers in Thailand, Japan, and the UK has shown a negative correlation between dengue hemorrhagic fever (DHF) and the density of the Aedes mosquitoes that transmit the virus. The study, published July 16th in the open-access journal PLoS Neglected Tropical Diseases, explains how current efforts to reduce the mosquitoes may actually increase the incidence of the potentially fatal viral disease.

A University of California, San Diego School of Medicine researcher has developed the first tissue culture of normal, human liver cells that can model infection with the Hepatitis C virus (HCV) and provide a realistic environment to evaluate possible treatments. The novel cell line, described in the July 16 issue of PLoS ONE, will allow pharmaceutical companies to effectively test new drug candidates or possible vaccines for the HCV infection, which afflicts about 170 million people worldwide. Currently, there is no animal model that is effective for testing such therapies.

Female monkeys are more dominant when they live in groups with a higher percentage of males. This is caused by self-organisation. This surprising discovery was made by researchers at the University of Groningen. What makes the study particularly interesting is that the researchers used a computer model which can simulate interaction between monkeys. Their findings will be published on July 16 in the open-access journal PLoS ONE.