Body

One of the smallest dinosaur skulls ever discovered has been identified and described by a team of scientists from London, Cambridge and Chicago. The skull would have been only 45 millimeters (less than two inches) in length. It belonged to a very young Heterodontosaurus, an early dinosaur. This juvenile weighed about 200 grams, less than two sticks of butter.

Researchers have put forward a simple model of development and gene regulation that is capable of explaining patterns observed in the distribution of morphologies and body plans (or, more generally, phenotypes). The study, by Elhanan Borenstein of the Santa Fe Institute and Stanford University and David Krakauer of the Santa Fe Institute was published in this month's issue of PLoS Computational Biology.

A recent study shows that genetic differences in Central Europe appear smaller than between and even within North European populations.

The study, led by researcher Päivi Lahermo from Institute for Molecular Medicine Finland (FIMM) and University of Helsinki, Finland, and professor Juha Kere from Karolinska Institutet, Sweden, will be published in PLoS ONE journal October 24th, 2008.

Many animals live longer when raised on low calorie diets. But now researchers at Washington University School of Medicine in St. Louis have shown that they can extend the life spans of roundworms even when the worms are well fed — it just takes a chemical that blocks their sense of smell.

Many rheumatologists and general internal medicine physicians in the US say they regularly prescribe "placebo treatments" including active drugs such as sedatives and antibiotics, but rarely admit they are doing so to their patients, according to a study on bmj.com today.

Despite the government's decision to choose the vaccine Cervarix for the UK human papillomavirus (HPV) vaccination programme, every doctor I have spoken to has chosen Gardisal for their own children, says a doctor on bmj.com today.

Phil Hammond, a general practitioner and broadcaster, shares his consultant colleague's recommendation ("you'd be mad not to protect your daughter against genital warts if you can afford to") and the HPV vaccine choice he made for his children.

Geneva, Switzerland: Analysis of data from several phase I and II clinical trials of a new cancer vaccine has shown it is capable of eliciting an immune response in most patients with bowel, kidney and prostate cancer, and that it may provide clinical benefit.

In a proportion of human solid tumors, in particular melanomas (a form of skin cancer that is often resistant to chemotherapy), inappropriate activation of the MEK/ERK signaling pathway as a result of mutations in the B-RAF gene promotes tumor cell growth and survival. Although MEK inhibitors stop such tumor cells growing, they have a limited ability to kill the tumor cells. Thus, they have had limited success in promoting tumor regression in preclinical and clinical trials.

Los Angeles, London, New Delhi, Singapore and Washington DC (October 23, 2008) In a study of medical students, more serious cardiac risk estimates were given to Christians and less serious estimates for Muslims despite the patients being otherwise identical in their characteristics and symptoms, according to research in an upcoming issue of Medical Decision Making published by SAGE. Risk assessment, the first step in a medical triage process, determines subsequent treatment.

Patients expect the most up-to-date equipment and technology at hospitals, regardless of the institution's size or budget. Providing that technology, however, can be difficult for small, rural hospitals that often lack the budget and staffing to make it possible.

A case study conducted by researchers in Penn State's College of Information Sciences and Technology (IST) shows that smaller hospitals may be able to benefit by sharing an IT infrastructure with larger hospitals in the same geographic area.

A Salmonella infection is not a positive experience. However, by infecting the common laboratory fruit fly Drosophila melanogaster with a Salmonella strain known for causing humans intestinal grief, researchers in the School of Life Sciences at Arizona State University have shed light on some key cell regulatory processes – with broad implications for understanding embryonic development, immune function and congenital diseases in humans.

Trees in a hyper-diverse tropical rainforest interact with each other and their environment to create and maintain diversity, researchers report in the Oct. 24 issue of the journal Science. This study was conducted in the Yasuni forest dynamics plot of the Pontificia Universidad Católica del Ecuador, the most diverse tropical forest site associated with the Center for Tropical Forest Science/Smithsonian Institution Global Earth Observatory network (CTFS/SIGEO).

Ghent, Belgium – VIB researchers at Ghent University have discovered the substance that governs the formation of root offshoots in plants, and how it works. Root offshoots are vitally important for plants – and for farmers. Plants draw the necessary nutrients from the soil through their roots. Because they do this best with a well-branched root system, plants must form offshoots of their roots at the right moment. The VIB researchers describe how this process is controlled in the prominent professional journal Science. A key player in this process is a protein called ACR4.

DURHAM, N.C. -- Patients operated on by surgeons who do not routinely remove cancer from the lungs may be at a higher risk for complications, according to a study conducted by researchers at Duke University Medical Center.

"Our study found that hospitals that do higher volumes of these types of surgeries have correspondingly lower mortality rates than those who do fewer of the procedures," said Andrew Shaw, M.D., an anesthesiologist at Duke and lead investigator on the study.

Amoebas glide toward their prey with the help of a protein switch that controls a molecular compass, biologists at the University of California, San Diego have discovered.

Their finding, detailed in this week's issue of the journal Current Biology, is important because the same molecular switch is shared by humans and other vertebrates to help immune cells locate the sites of infections.