Body

DURHAM, N.C. -- The cost of treating colorectal cancer varies widely, with newer, life-extending therapies sometimes costing tens of thousands of dollars more than older agents, according to a study led by a team of researchers in the Duke Comprehensive Cancer Center.

Saskatoon (November 3, 2008) – We all know physical activity is good for you. But why exactly is it good for you? What effect does exercise have on the cells and tissues of the body? What do we need to know so that we can use physical activity more effectively to combat chronic diseases such as arthritis, diabetes and heart disease? And what social and psychological factors prevent people from exercising or playing sports?

A newly developed equation produces more accurate estimates of the glomerular filtration rate (GFR)—a key indicator of kidney function in patients with chronic kidney disease (CKD), according to research being presented at the American Society of Nephrology's 41st Annual Meeting and Scientific Exposition in Philadelphia, Pennsylvania.

These days most children born with congenital heart disease live well into adulthood, thanks to innovative surgical, interventional and medical treatments. That means that not only are cardiologists caring for a growing number of adults with repaired heart defects, but the resulting cardiac anatomy and physiology are often much more complex than in the past.

Radiological health expert Daniel Hayes, Ph.D., of the New York City Department of Health and Mental Hygiene suggests that a form of vitamin D could be one of our body's main protections against damage from low levels of radiation. Writing in the International Journal of Low Radiation, Hayes explains that calcitriol, the active form of vitamin D, may protect us from background radiation and could be used as a safe protective agent before or after a low-level nuclear incident.

Kingston, ON – Although infection control has been substantially ramped up in Canadian hospitals since the SARS crisis of 2003, the number of resistant bacterial infections post-SARS have multiplied even faster, a new Queen's University study shows.

Led by Queen's epidemiologist Dr. Dick Zoutman, the national survey is a six-year follow-up to a study that was undertaken in 1999, prior to the outbreak of SARS (Severe Acute Respiratory Syndrome).

A unique approach to bone marrow transplantation pioneered in part by a Children's Hospital of Pittsburgh of UPMC physician has proven to be the only safe and effective cure for sickle cell disease, according to a new study.

COLUMBIA, Mo. – Even though investors use street earnings as a key valuation measure, little is known about analysts' rationale when determining street earnings. Street earnings are an adapted version of earnings based on modifications that are decided on a firm-by-firm basis and reflect analysts' decisions to include or exclude certain expenses. In a new study, a University of Missouri researcher found that analysts' self-interests often influence the value of street earnings, which makes street earnings less useful for predicting future earnings of high-growth stocks.

Long believed to be a disease of biblical times, leprosy, also known as Hansen's disease, continues to be seen in the United States. "Approximately 150 cases are diagnosed each year with 3,000 people in the U.S. currently being treated for leprosy, says James Krahenbuhl, Ph.D., director of the Health Resources Service Administration's National Hansen's Disease Program (NHDP) in Baton Rouge, LA.

The answer to successful revegetation of native flora is in sourcing genetically diverse seed not necessarily relying on remnant local native vegetation to provide seed.

"A common belief is that local native plants are the best source of seed for revegetation projects," says Dr Linda Broadhurst from CSIRO, Australia's national science agency.

"It has been presumed that local seed is adapted to local conditions and therefore it would provide the best results for restoration projects."

BOZEMAN, Mont. -- Montana State University scientists concerned about lethal mold infections have found a gene that regulates the mold's resistance to drugs.

The gene, called srbA, allows molds to thrive during infections even when inflammation reduces its oxygen supply, said Robert Cramer, senior author of a paper published in the Nov. 7 issue of PLoS Pathogens. When the gene is removed, the mold becomes much more vulnerable to lack of oxygen and can no longer grow to cause disease.

Patients whose nose has been destroyed by a tumor or injury carry a severe psychological and social burden. Esthetic reconstruction ranges among the most challenging tasks in plastic surgery. Helmut Fischer and Wolfgang Gubisch present the different options for nasal reconstruction surgery in the current issue of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2008; 105[43]:741-6).

Radical improvements in outcome for many cancer sufferers are in prospect following one of the most significant advances in radiotherapy since x-rays were first used to treat a tumour in 1904. The use of charged particles as an alternative to x-ray or gamma ray radiation can extend the scope of radiotherapy to tumours previously requiring invasive surgery, while speeding up diagnosis and reducing collateral damage to surrounding tissue.

Precautionary health measures such as mammograms and cholesterol tests that identify the risk of heart disease are critical for the well-being of women over 50. Add the responsibility of providing sustained care for a grandchild, and these preventive examinations become even more important.

Yet, grandmothers in the first two years of caring for a grandchild take fewer preventive measures to protect their health compared to grandmothers the same age not raising children, according to a recent USC Davis School of Gerontology study.

A gene mutation that causes high levels of uric acid in all Dalmatian dogs and bladder stones in some Dalmatians, has been identified by a team of researchers in the School of Veterinary Medicine at the University of California, Davis.

The discovery equips dog breeders with the tools to eliminate that trait from the Dalmatian breed and yields clues to the cause of similar problems in humans. The findings will be published Nov. 7 in the scientific journal Public Library of Science.