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HANOVER, NH – Two Dartmouth researchers call for greater scrutiny of the relationship between medical journalists and the health care industries they cover. Their study was published online today, Nov. 19, in the British Medical Journal, or BMJ.

The BMJ paper outlines three areas where journalists might become entangled in conflict-of-interest issues: during educational activities that may be drug company sponsored, when accepting sponsored awards, or in the day-to-day practice of reporting the news by relying too heavily on industry supplied sources.

(Washington) A white paper, How is a Shortage of Primary Care Physicians Affecting the Quality and Cost of Medical Care?, released today by the American College of Physicians (ACP) documents the value of primary care by reviewing 20 years of research. An annotated bibliography based on a literature review of more than 100 studies documents the evidence to support the critical importance of primary care in providing patients with better outcomes at lower cost, and the urgency of the need to prevent shortages of primary care physicians.

The TECNALIA Technological Corporation is leading research in Spain on The Future Internet through projects within the 7th EU Framework Programme such as m:Ciudad, MUGGES and 4WARD, with the aim of promoting a structural change in the Network of Networks and designing of a new architecture capable of providing the services of the next decades.

New Rochelle, NY, November 19, 2008—Biotech scientists increasingly are applying genomics technologies to toxicology research to better understand the effects of novel drug candidates on a variety of organ systems, reports Genetic Engineering & Biotechnology News (GEN). They are especially interested in figuring out a new compound's mechanism of action and eventually developing a predictive toxicology technique, according to the November 15 issue of GEN.

Philadelphia, November 19, 2008 - The American College of Physicians (ACP) and the Infectious Diseases Society of America (IDSA) have released a joint statement on the importance of adult vaccination against an increasing number of vaccine-preventable diseases. The statement has been endorsed by 17 other medical societies representing a range of practice areas.

According to the Centers for Disease Control and Prevention, 95 percent of vaccine-preventable diseases occur in adults and more than 46,000 adults die of vaccine-preventable diseases or their complications.

BETHLEHEM, PA (November 19, 2008)— A ban on fast food advertisements in the United States could reduce the number of overweight children by as much as 18 percent, according to a new study being published this month in the Journal of Law and Economics. The study also reports that eliminating the tax deductibility associated with television advertising would result in a reduction of childhood obesity, though in smaller numbers.

ATHENS, Ohio (Nov. 19, 2008) — A new class of compounds called phosphaplatins can effectively kill ovarian, testicular, head and neck cancer cells with potentially less toxicity than conventional drugs, according to a new study published this week in the journal Proceedings of the National Academy of Sciences.

MADISON, WI, NOVEMBER 17, 2008 -- One of the biggest threats to today's farmlands is the loss of soil organic carbon (SOC) and soil organic matter (SOM) from poor land-management practices. The presence of these materials is essential as they do everything from providing plants with proper nutrients to filtering harmful chemical compounds to the prevention of soil erosion. Sustainable management practices for crop residues are critical for maintaining soil productivity, but being able to measure a loss in the quality of soil can be difficult.

One of the most reliable indicators to predict that a person will develop type 2 diabetes is the presence of insulin resistance. Insulin is produced in the pancreas and is the hormone responsible for ensuring that glucose reaches several tissues and organs in the body, such as muscles. Insulin resistance is characterized by the lack of tissue response to insulin and is counteracted by a greater production of insulin by the pancreas.

A drug based on a chemical found in garlic can treat diabetes types I and II when taken as a tablet, a study in the new Royal Society of Chemistry journal Metallomics says.

When Hiromu Sakurai and colleagues from the Suzuka University of Medical Science, Japan, gave the drug orally to type I diabetic mice, they found it reduced blood glucose levels.

Two new compounds created by a University of Central Florida professor show early promise for destroying breast cancer tumors.

Associate Professor James Turkson's compounds disrupt the formation and spread of breast cancer tumors in tests on mice. The compounds, S3I-201 and S3I-M2001, break up a cancer-causing protein called STAT3, and researchers have observed no negative side effects so far.

"The compounds are very promising," Turkson said. "They've worked very well in mice, and now we're looking for partners to help us take these compounds to the next level of trials."

Almost every day brings news of an apparent breakthrough against cancer, infectious diseases, or metabolic conditions like diabetes, but these rarely translate into effective therapies or drugs, and even if they do clinical development usually takes well over a decade. One reason is that medical research is conducted in highly fragmented groups focusing on specific pathways or components leading to drugs that turn out not to work properly or to have dangerous side effects after cycles of animal and then clinical testing in humans.

[PRESS RELEASE, 19 November 2008] People who have attempted suicide at some point in their lives are more likely to actually succeed in committing suicide at a later date. The risk is particularly high for people with serious psychiatric disorder, according to a new study from the Swedish medical university Karolinska Institutet.

One in ten suicide attempters actually commit suicide later on in life. However, knowledge of the factors affecting the risk of suicide is limited, which makes it hard to identify, and help, the people who are at the greatest risk.

A study published in the scientific journal PLoS ONE highlights how the exploration of the ocean depths can benefit humankind. This is the story of a voyage of discovery, starting with marine animals that glow, the identification of the molecules responsible and their application as marker in living cells.

The first tissue-engineered trachea (windpipe), utilising the patient's own stem cells, has been successfully transplanted into a young woman with a failing airway. The bioengineered trachea immediately provided the patient with a normally functioning airway, thereby saving her life.

These remarkable results provide crucial new evidence that adult stem cells, combined with biologically compatible materials, can offer genuine solutions to other serious illnesses.