Body
Scientists at UCL have identified a new immunotherapy to combat the hepatitis B virus (HBV), the most common cause of liver cancer in the world.
Each year, globally, chronic HBV causes an estimated 880,000 deaths from liver cirrhosis and hepatocellular carcinoma/liver cancer (HCC).
The pioneering study used immune cells isolated directly from patient liver and tumour tissue, to show that targeting acyl-CoA:cholesterol acyltransferase (ACAT), an enzyme that helps to manage cholesterol levels in cells*, was highly effective at boosting immune responses.
A new study led by University of Liverpool researchers has confirmed that children with cystic fibrosis (CF) in the US have better lung function than UK children with the disease.
The study suggests that differences do not appear to be explained by early growth or nutrition, but could be linked to differences in the use of early treatments.
Epidemic. Pandemic. These terms have become second nature to us, popping up in everyday conversation, and for good reason -- COVID-19 is the latest pandemic to pose a threat to humanity.
But in recent months, far less attention has been paid to another widely spread problem that has been proliferating since the late 1970s: Lyme disease.
CHICAGO --- For men physicians, the professional perks of networking on social media, like being asked to give a talk, are abundant, a new Northwestern Medicine study reports.
For women physicians, the benefits are far less plentiful, the study found.
What's more, women physicians are more than twice as likely to be sexually harassed on social media than men physicians, according to an earlier study, published in January, of this same group of study participants.
White evangelicals are best persuaded to mask up through messages that stress the Christian doctrine of "love thy neighbor," according to a UCR-authored study published Tuesday.
The study yielded a second effective way to persuade white evangelicals - but only if they are Republican. That is, messaging from former President Donald Trump that aligns mask-wearing with patriotism.
The lessons learned from the study can be borrowed for pro-vaccine messaging, said study author Jennifer Merolla, a UCR professor of political science.
Researchers at Hospital for Special Surgery (HSS) have identified gaps in patient knowledge about pain management and opioid use before total hip replacement, including misconceptions about how much pain relief to expect from opioids after surgery, how to use multiple modes of pain relief (multimodal analgesia) safely and effectively, and proper opioid storage and disposal. These findings were presented at the 2021 Spring American Society of Regional Anesthesia and Pain Medicine (ASRA) Annual Meeting.1
Researchers at Hospital for Special Surgery (HSS) have identified risk factors for persistent opioid use after surgery in pediatric patients.1 Study findings were presented at the 2021 Spring American Society of Regional Anesthesia and Pain Medicine (ASRA) Annual Meeting.
Previous research indicates that prescription patterns for opioids after surgery in children and adolescents may be associated with long-term use and abuse.2
The need to evacuate an intensive care unit (ICU) or operating theatre complex during a fire or other emergency is a rare event but one potentially fraught with difficulty: not only is there a risk that patients may come to significant harm but also that staff may be injured and unable to work.
Therefore, the Association of Anaesthetists and the Intensive Care Society are today publishing new 2021 guidelines regarding fire safety and emergency evacuation of ICUs and operating theatres in Anaesthesia (a journal of the Association of Anaesthetists).
World-first nanotechnology developed by the University of South Australia could change the lives of thousands of people living with cystic fibrosis (CF) as groundbreaking research shows it can improve the effectiveness of the CF antibiotic Tobramycin, increasing its efficacy by up to 100,000-fold.
The new technology uses a biomimetic nanostructured material to augment Tobramycin - the antibiotic prescribed to treat chronic Pseudomonas aeruginosa lung infections in severe cases of CF - eradicating the infection in as little as two doses.
Cancer death rates have fallen dramatically in the United States, but factor in obesity, as researchers did at the University of North Carolina Gillings School of Global Public Health, and the picture changes.
In a study published May 10 in JAMA Network Open, researchers showed that obesity-related cancer deaths are improving, but at a slowing pace.
Pregnant Aussie mums are being denied access to medications which treat severe nausea and vomiting by pharmacists and medical practitioners because of misleading labels and a lack of awareness about clinical guidelines.
A new study surveyed 249 Australian women who suffered from severe nausea and vomiting during pregnancy (NVP) or hyperemesis gravidarum (HG) and examined their experiences in accessing medications during pregnancy.
In a study conducted by researchers at Hospital for Special Surgery (HSS), cumulative opioid use was reduced by 30% in a patient group that received duloxetine after total knee arthroplasty (TKA) compared with patients who received placebo. Patients who received duloxetine also reported higher pain management satisfaction and less pain interference with mood, walking, normal sleep, and work activities. These findings were presented at the 2021 Spring American Society of Regional Anesthesia and Pain Medicine (ASRA) Annual Meeting.1
COLUMBIA, Mo. - When Ram Raghavan heard from a former colleague at the Centers for Disease Control and Prevention that a 7-year-old girl had died from Rocky Mountain spotted fever as the result of a tick bite, he thought of his own daughter, also 7 years old at the time, and the potentially fatal danger posed to vulnerable populations by tick-borne diseases.
DALLAS - May 12, 2021 - Scientists with UT Southwestern's Peter O'Donnell Jr. Brain Institute have identified the molecular mechanism that can cause weight gain for those using a common antipsychotic medication. The findings, published in the Journal of Experimental Medicine, suggest new ways to counteract the weight gain, including a drug recently approved to treat genetic obesity, according to the study, which involved collaborations with scientists at UT Dallas and the Korea Advanced Institute of Science and Technology.
A small drug molecule that appears to protect normal tissue from the damaging effects of radiation, may simultaneously be able to boost the cancer-killing effect of radiation therapy, according to a new study led by scientists at University of Iowa, University of Texas Southwestern Medical Center, and Galera Therapeutics, Inc.