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Yale researchers are completing a first-of-its-kind clinical trial to test the efficacy of an automated bilingual alcohol screening and intervention tool for use in emergency departments (EDs). The computerized tool, administered to English- and Spanish-speaking Latino patient volunteers, is designed to address health disparities in the treatment of alcohol use disorders.
Scientists have taken a significant step forward in the search to find effective new drug candidates for the treatment of motor neurone disease.
Researchers from the Universities of Liverpool (UK) and Nagoya (Japan) have shown that a Selenium-based drug-molecule called ebselen and a number of other novel compounds developed at Liverpool can change many of the toxic characteristics of a protein, superoxide dismutase (SOD1), which causes some cases of Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease.
One year after the diagnosis of low-grade malignant brain tumor, a University of Gothenburg study shows, just under three people in ten were in full-time employment. Another year later, the proportion remained below half. For this young patient group, returning to work is a key health factor.
Every year, some 100 people in Sweden are diagnosed with low-grade brain tumor (also known as low-grade glioma). This type of tumor is incurable but grows slowly and, thanks to modern treatments, survival expectancy has successively increased.
Retinitis pigmentosa is the most prevalent form of congenital blindness. Using a retinitis pigmentosa mouse model, researchers from Ludwig-Maximilians Universitaet (LMU) in Munich have now shown that targeted activation of genes of similar function can compensate for the primary defect.
Sophia Antipolis, France - 1 Sept 2020: Restricting blood transfusion in anaemic heart attack patients to those with very low haemoglobin levels saves blood with no negative impact on clinical outcomes. That's the finding of the REALITY trial presented in a Hot Line session today at ESC Congress 2020.1
The work group around Henriette Uhlenhaut, Professor for Metabolic Programming at TUM School of Life Sciences in Freising-Weihenstephan and researcher in the field of Molecular Endocrinology at Helmholtz Zentrum München is working with so-called glucocorticoids. These are steroidal hormones such as cortisone, which are released by the adrenal glands every day before waking up or whenever a person is subjected to stress. These steroids are bound to their glucocorticoid receptor and control not only our body's immune reaction but also our sugar and fat metabolism.
When patients are discharged from Hospital those with diabetes are at an increased risk of readmission and mortality, there are guidelines for discharging patients with diabetes to reduce these risks, however researchers from the Institute of Digital Healthcare at WMG, University of Warwick and Warwick Medical School have identified known risk factors for mortality in adult patients discharged from hospital with diabetes.
Drugs used to treat initial signs of rheumatoid arthritis also improve the early stages of heart disease, according to new research.
Having rheumatoid arthritis (RA) is known to at least double the chances of developing cardiovascular disease (CVD) - one of the main causes of death and disability in the UK - because of links to atherosclerosis (a build-up of plaque inside the arteries), heart failure and strokes.
A two-year study by the University of Leeds has for the first time linked treatment of RA with improvements in vascular stiffness - an indicator of CVD.
Why so many COVID-19 patients get blood clots (thrombosis) remains uncertain. But scientists at Uppsala University and the University Hospital have now identified a mechanism they believe to be implicated. A particular protein triggers a part of our immune system that can boost the blood's tendency to coagulate and form clots. The study is now published in Thrombosis and Haemostasis.
Since thrombosis has proved to be a common complication in severe COVID-19, most people receiving hospital care for the disease get them.
When girls reach puberty at an unusually early age, they face a significantly higher risk of developing breast cancer later in life. Now, experts at Cincinnati Children's and the University of Cincinnati offer a new, unified explanation for why that increased risk occurs.
Sophia Antipolis, France - 31 Aug 2020: Blood pressure medication can prevent heart attacks and strokes - even in people with normal blood pressure. That's the finding of late breaking research presented in a Hot Line session today at ESC Congress 2020.1
Researchers at Flinders University are expanding work on a promising blood test model to help predict or diagnose head and neck cancer, a difficult cancer to pick up early and treat.
With cancer accounting for almost 10 million a year, the Global Burden of Disease report (2017) attributed more than 380,000 deaths to head and neck cancer.
Two recent studies were unable to rule out that H1N1 ("swine flu") vaccination ("Pandemrix") and seasonal influenza vaccination given to pregnant women might be associated with autism-spectrum disorder in the offspring. Now, a large study by researchers at Karolinska Institutet in Sweden, published in the journal Annals of Internal Medicine, refutes any such association.
Data presented at one of the opening sessions at this year's European and International Congress on Obesity (ECOICO 2020) held online this year (1-4 September) will show the clear relationship between obesity and the severity of COVID-19 disease. The session is presented by François Pattou, Professor of Surgery at the Faculty of Medicine of the University of Lille, and head of the Department of General and Endocrine Surgery at Lille University Hospital, France.
NEW YORK, NY--A new study of the antibodies produced by people with gluten sensitivity may lead to a better way to detect the condition and treat it.
Until recently, many doctors often dismissed the complaints of people who claimed to be sensitive to foods containing gluten but did not have celiac disease, a well-documented autoimmune disease triggered by exposure to the dietary protein found in wheat, rye, and barley.