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In 1997, the very first Neandertal DNA sequence - just a small part of the mitochondrial genome - was determined from an individual discovered in the Neander Valley, Germany, in 1856. Since then, improvements in molecular techniques have enabled scientists at the Max Planck Institute for Evolutionary Anthropology to determine high quality sequences of the autosomal genomes of several Neandertals, and led to the discovery of an entirely new group of extinct humans, the Denisovans, who were relatives of the Neandertals in Asia.
A new study led by a cardiologist from Brigham and Women's Hospital has assessed the cardiovascular and renal outcomes for ertugliflozin, an SGLT2 inhibitor prescribed for patients with type 2 diabetes to help them control blood sugar levels. The Evaluation of Ertugliflozin Efficacy and Safety Cardiovascular Outcomes Trial (VERTIS CV) found that the drug had a safety profile similar to that of other SGLT2 inhibitors and did not increase risk of major adverse events compared to the placebo.
Researchers in the University of São Paulo’s School of Physical Education and Sports (EEFE-USP) in Brazil compared the effect of two widely used classes of anti-hypertensive drugs on post-exercise hypotension, an expected and beneficial fall in blood pressure after a session of aerobic exercise, especially in the late afternoon or early evening.
According to the researchers, the findings of their study can help health professionals choose the most beneficial time of day for patients to undergo physical therapy depending on the type of drug used to treat their high blood pressure.
BOSTON -Many people are feeling anxious during these uncertain times as they navigate the risks associated with COVID-19 and experience the tension from physical distancing or isolation for what can seem like an eternity. But people of Asian ancestry face yet another set of challenges posed by racism and xenophobia which has soared during the COVID-19 pandemic amidst rumors and blame placed on China.
Adults conceived through sperm donation reported higher frequencies of allergies, type 1 diabetes and other autoimmune conditions in a world-first study that examined the long term health outcomes of donor-conceived people.
The study was conducted by Flinders University's Caring Futures Institute, led by researcher Damian Adams, and published in the Journal of Developmental Origins of Health and Disease. It looked at 272 donor-conceived adult participants from around the world together with 877 who were conceived naturally.
In an impressive proof-of-concept demonstration, an interdisciplinary team of scientists has developed a bioelectronic system driven by a machine learning algorithm that can shift the membrane voltage in living cells and maintain it at a set point for 10 hours.
A new study presented at this year's annual meeting of the European Association for the Study of Diabetes (EASD) shows the disproportionate impact of early-onset adult type 2 diabetes (T2D) on individuals of South Asian and African-Caribbean ethnicity in the UK.
New research presented at this year's annual meeting of the European Association for the Study of Diabetes (EASD) shows that high-intensity interval training (HIIT) combining cycling and rowing markedly improves insulin sensitivity, body composition and cardiorespiratory fitness in cases of obesity and type 2 diabetes (T2D). The study is by Dr Maria Petersen and colleagues at Steno Diabetes Centre Odense, Odense University Hospital, Odense, Denmark.
New research from the UK, being presented at this week's ESCMID Conference on Coronavirus Disease (ECCVID, online from 23-25 September) shows that the diagnosis of several common conditions including cardiovascular and cerebrovascular (circulatory) disease, diabetes, and mental health conditions approximately halved during the country's COVID-19 lockdown. The study is to be published in The Lancet Public Health ahead of a special conference session featuring The Lancet journals.
New research being presented at the ESCMID Conference on Coronavirus Disease (ECCVID, online 23-25 September) shows that, in a head-to-head comparison of five tests used to detect SARS-CoV-2 antibodies (known as 'immunoassays'), an assay manufactured by Siemens and one developed by an academic partnership led by the University of Oxford had the most accurate results. The study is published in The Lancet Infectious Diseases, as part of a special ECCVID session featuring The Lancet journals.
New research presented at this week's ESCMID Congress on Coronavirus Disease (ECCVID, held online 23-25 September) shows that outbreaks of COVID-19 in elderly care homes were caused by multiple independent infections from outside, plus within care home spread. There is also evidence of transmission between residents and healthcare workers, including paramedics, possibily linking care home outbreaks to hospital outbreaks (though the direction of transmission between individuals could not be confirmed).
ORLANDO, Sept. 23, 2020 - A new National Science Foundation-funded survey of six states has found that during the past two months, more people are wearing masks, vaccine uncertainty is on the rise, and many people are overestimating their risk of becoming seriously ill and dying from COVID-19.
The results are in a new report published this month by the Risk and Social Policy Group, a team of more than 15 scholars across the country that includes University of Central Florida associate professor Lindsay Neuberger.
Using a device that could be built with a dollar's worth of open-source parts and a 3D-printed case, researchers want to help the hundreds of millions of older people worldwide who can't afford existing hearing aids to address their age-related hearing loss.
BOSTON - A standard test that assesses blood cells can identify which patients who are admitted to the hospital with COVID-19 face a high risk of becoming critically ill and dying. This discovery, which is described in JAMA Network Open, was made by a team of investigators at Massachusetts General Hospital (MGH) based in the MGH Center for Systems Biology.
What The Study Did: This observational study used data from the Department of Veterans Affairs (VA) health care system to examine what risk factors are associated with hospitalization, mechanical ventilation and death among patients with SARS-CoV-2 infection.
Authors: George N. Ioannou, B.M.B.Ch., M.S., of the Veterans Affairs Puget Sound Healthcare System and the University of Washington in Seattle, is the corresponding author.