Body

It's generally accepted health advice that adults of all ages should sit less, move more, and engage in regular exercise to feel better and reduce the risk of chronic diseases. However, when it comes to the brain and cognition, a new study of older adults from Colorado State University suggests that some sedentariness isn't all bad, so long as basic physical activity benchmarks are being met.

A new study by UBC researchers is set to change international treatment recommendations for people who are newly diagnosed with HIV--an update that could affect nearly two million people per year worldwide.

NEW YORK - October 16, 2020 - In the FORECAST randomized clinical trial, the use of fractional flow reserve management derived from computed tomography (FFRCT) did not significantly reduce costs but did reduce the use of invasive coronary angiography (ICA).

Findings were reported today at TCT Connect, the 32nd annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine.

A new study has found that Vietnamese-American adults who were not obese were 60% more likely to have diabetes than non-obese, non-Hispanic, White Americans, after accounting for age, sex, sociodemographic factors, smoking history and exercise level.

Overall, only 9% of Vietnamese Americans with diabetes in the study were obese -- defined as having a body mass index (BMI) of 30 or higher. In comparison, half of all non-Hispanic White Americans with diabetes were obese.

A study published in the journal Science and coordinated by researchers of IDIBAPS, the UB and teh Spanish National Center of Cardiovascular Research (CNIC) describes a new immune defence mechanism unknown until now. It is a mechanism orchestrated by lipid droplets (LDs), the cellular organelles capable of attracting and eliminating invading pathogens.

Peer reviewed / Randomised clinical trial / People

The Lancet Infectious Diseases: Preliminary results find vaccine candidate based on inactivated SARS-CoV-2 virus is safe and induces an immune response in healthy volunteers

Phase 1/2 randomised controlled trial of an inactivated SARS-CoV-2 vaccine candidate was carried out in China between 29 April and 30 July 2020 and involved more than 600 healthy volunteers.

Study detected antibody responses in all recipients by day 42 after vaccination, and provides some data for participants aged over 60 years.

Silver Spring, Md.--Scientists from across the globe will present the latest research in obesity science and medicine and related topics at the 38th Annual Meeting of The Obesity Society (TOS) at ObesityWeek® Interactive. This online event will take place Nov. 2-6, 2020 at http://www.obesityweek.org. On-Demand materials and other elements of the interactive conference will remain available online through Dec. 31, 2020.

In the largest clinical trial of its kind, researchers show that combining sound and electrical stimulation of the tongue can significantly reduce tinnitus, commonly described as "ringing in the ears." They also found that therapeutic effects can be sustained for up to 12 months post-treatment.

A laboratory test developed by a research team led by Johns Hopkins University bioengineers can accurately pinpoint, capture and analyze the deadliest cells in the most common and aggressive brain cancer in adults.

The method's ability to capture the invasive proliferating and very mobile cells in the fatal condition called glioblastoma could lead to the discovery of new drugs to prevent or slow the cancer's spread. The test can also accurately predict which patients have the least or most aggressive form of glioblastoma.

New research from the International Collaboration on Repair Discoveries (ICORD) challenges the current standard for managing blood pressure in people with spinal cord injury (SCI).

The findings, published today in Nature Communications, could lead to a change in the way newly injured patients have their blood pressure managed, potentially improving their chances of retaining more function in the long term.

NEW YORK - October 15, 2020 - The MITHRAS randomized clinical trial found that interventional closure of an iatrogenic atrial septal defect (iASD) driven by transcatheter mitral valve repair (TMVR) was not superior to conservative medical treatment with regard to the primary endpoint of change in six-minute walking distance.

NEW YORK - October 14, 2020 - New data from PROSPECT ABSORB, a pilot randomized trial of percutaneous coronary intervention (PCI) of non-flow-limiting vulnerable plaques in native coronary arteries, found that PCI was safe, substantially enlarged follow-up lumen areas, and was associated with favorable long-term clinical outcomes.

NEW YORK - October 14, 2020 - Data from COMBINE (OCT-FFR) found that the use of FFR combined with OCT imaging can help improve the accuracy of high-risk lesion identification in patients with diabetes.

Findings were reported today at TCT Connect, the 32nd annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine.

LA JOLLA, Calif. (October 15, 2020) -- Cannabidiol (CBD) is a chemical found in hemp or marijuana plants that does not make users high.

Findings by Monash Biomedicine Discovery Institute (BDI) researchers have pointed to a new combination of treatments that may help breast cancer patients with certain gene mutations.

The study, published in Molecular Cell and led by Dr Antonella Papa, identified potential new treatments for patients who lacked PTEN, a gene that suppresses tumours, and/or have mutations in the cancer gene PI3K.