Body

Patients with cancer have multiple treatment options available to them today, but each has its drawbacks. Chemotherapy kills rapidly dividing cancer cells, but it also damages healthy cells in the body and often does not effectively prevent tumor metastasis or disease recurrence. Immunotherapies avoid those problems by acting on a patient's immune system to generate a sustained anti-cancer response, but frequently have trouble accessing tumors due to the immunosuppressive local environment that tumors create.

Scientists have developed an optical elastography technique that could revolutionise the accuracy and ease to which health professionals can detect biomechanical alterations of cells and tissues.

A study derived by an international collaboration between the University of Exeter, Gloucestershire Hospitals NHS Foundation Trust, the University of Perugia (Italy) and the Institute of Materials of the National Research Council of Italy (IOM-CNR) applied an innovative biophotonic approach to highlight how the microscopic processes drive mechanical modification in biological tissues.

Treating Opioid Addiction in Primary Care Benefits Both Patients and Cash-Strapped Medical Practices

The Xavante, one of the indigenous communities most vulnerable to SARS-CoV-2 in Brazil, are suffering from an epidemic of diabetes, a “silent” disease considered a risk factor for severe COVID-19.

A group of researchers affiliated with the Federal University of São Paulo’s Medical School (EPM-UNIFESP) and the University of São Paulo’s Ribeirão Preto Medical School (FMRP-USP) examined the retinas of 157 individuals before the COVID-19 pandemic and found a high prevalence of type 2 diabetes and eye disorders caused by the disease.

Buprenorphine-based treatment for opioid addiction is in short supply in many areas of the United States. And while many physicians want to offer it, clinics are unsure how to offer buprenorphine therapy in a financially sustainable way. A team of researchers at Harvard Medical School conducted financial cost and revenue analysis for four different approaches to delivering buprenorphine-based treatment in primary care practices.

Peer-reviewed / 1 Observational study + 1 Systematic review and meta-analysis / People

An observational study finds risk of heart attack and cardiovascular disease is highest in people aged 70 and over with elevated levels of LDL cholesterol, compared to younger age groups, and estimates the number needed to treat with statins to prevent one heart attack in five years is lowest in people aged 70 to 100 years.

Kanazawa, Japan - The relationship between dietary habits and the occurrence of chronic kidney disease (CKD) is not fully known. In a new study, researchers from Kanazawa University found out that skipping breakfast and late dinner might be associated with a higher risk of proteinuria which is a key prognostic factor of CKD.

Researchers from Tokyo Medical and Dental University (TMDU) report a case of frosted branch angiitis in a woman presenting years after being treated for leukemia-lymphoma with allogeneic human stem cell transplant.

Working in farming or the wood industry while suffering from asthma is not a good combination. This is because it increases the risk of being hospitalised again with asthma. This is shown by a new study from Aarhus University.

The first COVID-19 vaccines could be authorised as early as the start of 2021. However, in all likelihood, there will not be sufficient vaccine doses in the beginning for all the people willing to undergo vaccination. This is why prioritisation will be necessary. In the position paper published today, medical-epidemiological aspects of infection prevention are presented alongside ethical, legal and practical considerations. On this basis, the authors develop a framework for action for the initial prioritisation of vaccination measures against COVID-19.

Many environmental and lifestyle factors have been implicated in the decline of sperm quality, with diet being one of the most plausible factors identified in recent years. Moreover, several studies have reported a close association between the alteration of specific sperm DNA methylation signatures and semen quality. To date, however, no randomized clinical trials (RCT) have been published that assess the effects of diet on these changes in the function of sperm DNA.

November 9, 2020 - Men undergoing active surveillance for prostate cancer have very low rates - one percent or less - of cancer spread (metastases) or death from prostate cancer, according to a recent study published in The Journal of Urology®, an Official Journal of the American Urological Association (A

Online consumer reviews play an important role in almost every consumer industry -- from dining and shopping to travel and technology. But what do online reviews of physicians tell consumers?

In a new study, researchers from The University of Texas at Dallas investigated whether patient-generated online reviews of physicians accurately reflect the quality of care.

Receiving an initial antibiotic prescription for a viral acute respiratory infection--the type of infection that doesn't respond to antibiotics--increases the likelihood that a patient or their spouse will seek care for future such infections and will receive subsequent antibiotic prescriptions, according to the findings of a study from Harvard Medical School and the Harvard T.H. Chan School of Public Health.

November 9, 2020 - The recently FDA-authorized alpha-defensin lateral flow test is a highly accurate, ten-minute test for diagnosis of periprosthetic joint infection (PJI) - a serious and costly complication of total joint replacement, reports a study in