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Small studies have suggested that a group of medications called RAS inhibitors may be harmful in persons with advanced chronic kidney disease, and physicians therefore often stop the treatment in such patients. Researchers at Karolinska Institutet now show that although stopping the treatment is linked to a lower risk of requiring dialysis, it is also linked to a higher risk of cardiovascular events and death. The results are published in The Journal of the American Society of Nephrology.
Despite recommendations, patients with treatment-resistant hypertension rarely tested for primary al
Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, but also on behalf of the organization they represent.
What The Study Did: The likelihood of having obesity or eating disorders was compared between sexual and gender minority children ages 9 to 10 and other children in this study.
Authors: Natasha A. Schvey, Ph.D., of the Uniformed Services University of the Health Sciences in Bethesda, Maryland, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamapediatrics.2020.5152)
E-cigarette use has risen steeply and mostly without regulation over the past decade. The devices have diversified into a dizzying array of vape pens, tank systems, "mods," and more, mass-marketed and sold to the public. The U.S. Food and Drug Administration (FDA) is in the midst of considering whether to approve thousands of pre-market applications for the sale of e-cigarettes as consumer products.
A landmark paper published today in the New England Journal of Medicine describes the results from a global trial across 148 sites in 23 countries, showing a 30 per cent improvement in survival in patients with acute myeloid leukemia (AML).
The use of a standardized tool for assessing the risk of serious outcomes in patients with chest pain was associated with women at high risk receiving comparable care to men, according to new research published in the Annals of Emergency Medicine. Care received by women at low and intermediate risk was consistent with current clinical recommendations. Men received more stress testing and were more likely to be hospitalized than women.
What The Viewpoint Says: This Viewpoint discusses initiatives of the U.S. Food and Drug Administration's Oncology Center of Excellence to address COVID-19-related challenges faced by patients with cancer and the health care professionals who provide cancer treatment.
Authors: Jennifer J. Gao, M.D., of the Oncology Center of Excellence at the FDA in Silver Spring, Maryland, is the corresponding author.
New research into this question shows that the second wave of an epidemic is very different if a population has a homogenous distribution of contacts, compared to the scenario of subpopulations with diverse number of contacts.
Researchers from SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health, have shown that a triple drug combination - of irinotecan, cetuximab, and vemurafenib - is a more powerful tumor fighter and keeps people with metastatic colon cancer disease free for a significantly longer period of time compared with patients treated with irinotecan and cetuximab.
The key conclusion of the study was not a surprise to the scientists involved: the importance of social media as a primary communication channel grows during a crisis. Inversely, the topicality of the limited regulation of social media lessens. We are seeing a trend in different countries, Estonia among them, of official news being first broadcast on social media.
Announcing a new publication for BIO Integration journal. In this review article the authors Zeling Guo, Shanping Jiang, Zilun Li and Sifan Chen from Sun Yat-Sen University, Guangzhou, China review how metabolic syndrome "interacts" with COVID-19.
BOSTON -- In a perspective published in the Journal of Hospital Medicine, experts from the Massachusetts General Hospital (MGH) Department of Medicine, Office of Equity and Inclusion and Center for Diversity and Inclusion call for a more inclusive and culturally competent ap-proach to clinical care based on best practices developed during the COVID-19 surge in Massachusetts.
New Rochelle, NY, December 22, 2020--Women were 39% more likely to die by 1 year after a first stroke. The sex difference was due to advanced age and more severe strokes in women, according to a new study in the Journal of Women's Health. Click here to read the article now.
Among women and men with a first-ever stroke, women were approximately 7 years older. In addition, 9.3% fewer women could walk independently on admission to the hospital, suggestive of a more severe stroke.