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The dream team: Scientists find drug duo that may cure COVID-19 together
While preventative care for COVID-19 has made much noise (with vaccines having rolled out in most countries), the soaring infection rates indicate the need for effective treatments. Using cultured cells to study SARS-CoV-2 infections, researchers at the Tokyo University of Science and other institutions have discovered that the drugs cepharanthine and nelfinavir are effective at combating the virus, with the former preventing the virus from entering cells and the latter preventing the virus from replicating.
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Mockingbird song decoded
Mockingbirds follow similar musical rules as those found in human music, from Beethoven to Kendrick Lamar.
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Athletic competition after COVID
Cardiovascular imaging demonstrated no evidence of myocardial injury or myocarditis in athletes after COVID-19 infection, according to a research letter published in Circulation by Le Bonheur Children's Hospital and the University of Tennessee Health Science Center cardiologists.
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Secret shopper study sheds light on barriers to opioid treatment for women
After a 2020 Vanderbilt University Medical Center study showed women have a difficult time accessing treatment for opioid use disorder (OUD), investigators analyzed comments received from the study's participants to further shed light on barriers to care, which included everything from long on-hold times to difficult interactions with clinic receptionists during phone calls seeking appointments.
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Genetic base editing treats sickle cell disease in mice
Sickle cell disease leads to chronic pain, organ failure, and early death in patients worldwide. A team led by Broad Institute of MIT and Harvard and St. Jude Children's Research Hospital has demonstrated a gene editing approach that efficiently corrects the mutation underlying SCD in patient blood stem cells and in mice. This treatment rescued disease symptoms in animal models, enabling long-lasting production of healthy blood cells, and could inspire a therapeutic strategy for SCD.
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South Pole and East Antarctica warmer than previously thought during last ice age, two studies show
University of Washington glaciologists are co-authors on two papers that analyzed Antarctic ice cores to understand the continent's air temperatures during the most recent glacial period. The results help understand how the region behaves during a major climate transition.
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Scientists discover new approach to stabilize cathode materials
UPTON, NY--A team of researchers led by chemists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory has studied an elusive property in cathode materials, called a valence gradient, to understand its effect on battery performance. The findings, published in Nature Communications, demonstrated that the valence gradient can serve as a new approach for stabilizing the structure of high-nickel-content cathodes against degradation and safety issues.
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COVID's impact on pregnancy, birth trends
The COVID-19 shutdown initially seemed to hit pause on pregnancy and birth rates, new research from one major hospital system suggests, but that trend is quickly reversing.
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URI scientists discover function of microbes living in oysters
Scientists from the University of Rhode Island have taken the first steps toward understanding the function of microbes that live on and in Eastern oysters, which may have implications for oyster health and the management of oyster reefs and aquaculture facilities.
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Researchers design simulation tool to predict disease, pest spread
North Carolina State University researchers have developed a computer simulation tool to predict when and where pests and diseases will attack crops or forests, and also test when to apply pesticides or other management strategies to contain them.
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Shoot better drone videos with a single word
A team from Carnegie Mellon University, the University of Sao Paulo and Facebook AI Research developed a model that enables a drone to shoot a video based on a desired emotion or viewer reaction. The drone uses camera angles, speeds and flight paths to generate a video that could be exciting, calm, enjoyable or nerve-wracking -- depending on what the filmmaker tells it.
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Analyzing tumor microenvironment at single cell level sheds light on metastatic melanoma outcomes
In a new article published in Clinical Cancer Research, Moffitt Cancer Center researchers reveal how different therapies impact the surrounding immune environment of metastatic melanoma tumors according to location and identify a rare population of immune cells that is associated with improved overall survival.
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CO2 emissions are rebounding, but clean energy revolutions are emerging
According to a new University of California San Diego article published in Nature Energy there are encouraging signs in emerging clean energy technology "niches"--countries, states or corporations--that are pioneering decarbonization.
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Linked faults under Salt Lake City may elevate risk of building damage
A complex zone of folding and faulting that links two faults underneath downtown Salt Lake City could deform the ground during a large earthquake, according to a new study.
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Immune therapy after surgery lowers relapse risk in patients with high-risk melanoma
Patients with high-risk melanoma who had a course of pembrolizumab after their surgery had a longer time before their disease recurred than patients who got either ipilimumab or high-dose interferon after surgery. These findings of a large SWOG Cancer Research Network clinical trial, S1404, will be presented at the ASCO annual meeting June 6, 2021.
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Study on heavy drinking in young adults and the psychological impacts of COVID-19
In a sample of nearly 500 young adults ranging in age from 18 to 25, researchers saw a reduction in problematic drinking and alcohol consequences during the initial phase of the pandemic for both men and women. Additional findings showed increased rates of depression and anxiety symptoms among young women.
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New method accurately reflects hotspots in epidemic
A new method to monitor epidemics like COVID-19 gives an accurate real-time estimate of the growth rate of an epidemic by carefully evaluating the relationship between the amount of viruses in infected people's bodies, called the viral load, and how fast the number of cases is increasing or decreasing.
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NIH researchers identify potential new antiviral drug for COVID-19
The experimental drug TEMPOL may be a promising oral antiviral treatment for COVID-19, suggests a study of cell cultures by researchers at the National Institutes of Health.
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Antarctica wasn't quite as cold during the last ice age as previously thought
A study of two methods for reconstructing ancient temperatures has given climate researchers a better understanding of just how cold it was in Antarctica during the last ice age around 20,000 years ago.
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Studies reveal skull as unexpected source of brain immunity
Researchers at Washington University School of Medicine in St. Louis have discovered that the immune cells that protect the brain and spinal cord come primarily from the skull. The finding opens up the possibility of developing therapies to target such cells as a way to prevent or treat brain conditions.
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