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Toward a feasible alternative to liver organ transplant

Eurekalert - Apr 27 2021 - 00:04
New insights into how fetal and adult liver cells differ could be used to help make liver cell transplants successful long term. Transplanting functioning liver cells into a patient's liver can help replace liver function that is impaired due to disease.
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Study illuminates how COVID-19 worms its way into the brain

Eurekalert - Apr 27 2021 - 00:04
New research offers an up-close view of how SARS-CoV-2, the virus that causes COVID-19, can spread to the brain. The study helps explain the alarming array of neurological symptoms reported in some patients with COVID-19, as well as why some patients suffer severe neurological effects while others experience none at all.
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'Smart shirt' takes a trip to space for science

Eurekalert - Apr 27 2021 - 00:04
A technology-packed tank top offers a simple, effective way to track astronauts' vital signs and physiological changes during spaceflight, according to research being presented at the American Physiological Society annual meeting during the Experimental Biology (EB) 2021 meeting, held virtually April 27-30.
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SARS-CoV-2 spike protein alone may cause lung damage

Eurekalert - Apr 27 2021 - 00:04
Using a newly developed mouse model of acute lung injury, researchers found that exposure to the SARS-CoV-2 spike protein alone was enough to induce COVID-19-like symptoms including severe inflammation of the lungs.
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Researchers uncover potential new way to treat dry mouth

Eurekalert - Apr 27 2021 - 00:04
Researchers studying mice made a serendipitous discovery that could lead to a new dry mouth treatment. More than 10% of people experience dry mouth, which can be caused by medical conditions, radiation treatment, certain medications and aging.
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Researchers design sensor for fast, inexpensive on-site Ebola detection

Eurekalert - Apr 27 2021 - 00:04
Researchers are developing a new sensor that can detect Ebola in a single drop of blood and provides results in just an hour. With further development, the technology might also enable fast and inexpensive detection of other viruses, including the virus that causes COVID-19.
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Plant compound shows promise against triple-negative breast cancer

Eurekalert - Apr 27 2021 - 00:04
Findings from a new cell study suggest that the natural plant compound sanguinarine could be a promising tool for targeting triple-negative breast cancer cells. The researchers also found that breast cancer cells derived from people with African American ancestry were more sensitive to sanguinarine than those of European origin.
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How does a nose evolve into a blowhole? Study suggests there's more than one way

Eurekalert - Apr 27 2021 - 00:04
The two major types of cetaceans appear to have evolved their characteristic blowholes through different anatomical transformations, according to a study being presented at the American Association for Anatomy annual meeting during the Experimental Biology (EB) 2021 meeting, held virtually April 27-30.
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Gene changes might explain long-haul COVID-19 symptoms

Eurekalert - Apr 27 2021 - 00:04
Results from a new cell study suggest that the SARS-CoV-2 spike protein can bring about long-term gene expression changes. The findings could help explain why some COVID-19 patients -- referred to as COVID long-haulers -- experience symptoms such as shortness of breath and dizziness long after clearing the infection.
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Five studies point to dangers of environmental exposures

Eurekalert - Apr 27 2021 - 00:04
Recent years have brought increased attention to the lasting effects of chemicals we unwittingly inhale, touch and ingest while going about our daily lives. The Experimental Biology (EB) 2021 meeting features the latest research on how environmental exposures affect health.
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Five new insights in the fight against COVID-19

Eurekalert - Apr 27 2021 - 00:04
Scientists from around the world are gathering to share the latest research at the forefront of biology during the Experimental Biology (EB) 2021 meeting. Many sessions focus on the year's most pressing priorities in bioscience: COVID-19 and the virus that causes it, SARS-CoV-2.
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Depression medication could also protect against heart disease

Eurekalert - Apr 27 2021 - 00:04
The antidepression drug duloxetine could be beneficial to patients with both depression and cardiovascular disease, according to new studies performed in human blood and in mice. Globally, more than 300 million people have depression, which comes with an increased risk of developing cardiovascular disease.
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Could corals use sound to communicate?

Eurekalert - Apr 27 2021 - 00:04
Corals are part of a highly complex ecosystem, but it remains a mystery if and how they might communicate within their biological community. In a new study, researchers found evidence of sound-related genes in corals, suggesting that the marine invertebrates could use sound to interact with their surroundings.
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Compound found in some vegetables may reduce diabetes-related kidney damage

Eurekalert - Apr 27 2021 - 00:04
New research conducted in rats suggests a compound that gives some cruciferous vegetables their pungent taste could help to reverse kidney problems associated with diabetes.
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Capsaicin analog could help treatment-resistant lung cancer

Eurekalert - Apr 27 2021 - 00:04
A new study found that non-pungent synthetic analog of capsaicin -- the compound that makes chili peppers hot -- made small cell lung cancer cells more responsive to treatment. Small cell lung cancer is a very aggressive form of cancer with a low survival rate.
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Using big data to save babies

Eurekalert - Apr 27 2021 - 00:04
Although bronchopulmonary dysplasia (BPD)--a chronic lung disease affecting newborns--is the most common complication of preterm birth, it remains difficult to diagnose and treat. Researchers from Fundación INFANT in Buenos Aires, Argentina, and The University of Oklahoma Health Sciences Center, hope to address these difficulties using machine learning to inform the clinical care of preemies with BPD. The team will present their work virtually at the American Physiological Society's (APS) annual meeting at Experimental Biology 2021.
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Brain development is surprisingly similar between humans and other primates

Eurekalert - Apr 27 2021 - 00:04
What makes the human brain special? It's not the time it takes to mature, according to new research. Scientists report the human frontal cortex, the part of the brain involved in higher-level thinking and reasoning, follows a developmental trajectory similar to that of other primates including chimpanzees and macaques.
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Urine of COVID-19 patients could predict who will develop severe disease

Eurekalert - Apr 27 2021 - 00:04
Urine analysis of COVID-19 patients revealed elevated levels of specific biomarkers of the immune system compared to those who were not infected with the coronavirus. In addition, levels of these inflammatory markers were higher in patients with comorbidities such as high blood pressure and diabetes, according to researchers from Wayne State University in Detroit. The findings will be presented virtually at the American Physiological Society's (APS) annual meeting at Experimental Biology 2021.
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Self-reported daytime sleepiness is associated with telomere shortening

Eurekalert - Apr 27 2021 - 00:04
People who self-report daytime sleepiness were found to have shorter telomeres regardless of whether they had obstructive sleep apnea, according to a new study from researchers at the Mayo Clinic in Rochester, Minnesota. The findings will be presented virtually at the American Physiological Society's (APS) annual meeting at Experimental Biology 2021.
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Rapamycin may exacerbate age-related arthritis despite life-extending benefits

Eurekalert - Apr 27 2021 - 00:04
New research to be presented this week virtually at the American Physiological Society's (APS) annual meeting at Experimental Biology 2021 explores the positive and negative effects of lifespan-extending drugs on mitochondrial function and age-related osteoarthritis (OA).
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