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How ethane-consuming archaea pick up their favorite dish

Eurekalert - Jul 02 2021 - 00:07
Hot vents in the deep sea are home to microbes that feed on ethane. They were discovered recently from scientists of the Max Planck Institute for Marine Microbiology. Now the researchers from Bremen succeeded in finding an important component in the microbial conversion of the gas. They were able to decode the structure of the enzyme responsible for the ethane fixation. The results have now been published in the renowned journal Science.
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Medical journal articles written by women are cited less than those written by men

Eurekalert - Jul 02 2021 - 00:07
Articles published by women in high-impact medical journals also have fewer citations than those written by men, especially when women are primary and senior authors, according to new research.
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Identifying hospitals with a high proportion of patients with social risk factors

Eurekalert - Jul 02 2021 - 00:07
What The Study Did: This study investigates whether different risk factors identify the same hospitals caring for a high proportion of disadvantaged patients using seven definitions of social risk.
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Surprise bills for childbirth

Eurekalert - Jul 02 2021 - 00:07
What The Study Did: Researchers estimated the frequency and magnitude of surprise bills for deliveries and newborn hospitalizations, which are the leading reasons for hospitalization in the United States, to illustrate the  potential benefits of federal legislation that will protect families from most surprise bills.
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Women's use of preventive health services during COVID-19

Eurekalert - Jul 02 2021 - 00:07
What The Study Did: Changes in the use of women's preventive health services during the COVID-19 pandemic, including screening for sexually transmitted infections, breast and cervical cancer, and obtaining contraceptives from pharmacies are described by researchers in this study.
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Evaluation of health equity in COVID-19 vaccine distribution plans in US

Eurekalert - Jul 02 2021 - 00:07
Researchers in this study aimed to determine how each state and the District of Columbia planned to ensure equitable COVID-19 vaccine distribution.
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Potential drug target for difficult-to-treat breast cancer: RNA-binding proteins

Eurekalert - Jul 02 2021 - 00:07
UC San Diego studies using human cell lines and tumors grown in mice provide early evidence that inhibiting RNA-binding proteins, a previously overlooked family of molecules, might provide a new approach for treating some cancers.
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Methylglyoxal detoxification deficits causes schizophrenia-like behavioral abnormalities

Eurekalert - Jul 02 2021 - 00:07
We generated a mouse model for a subgroup of schizophrenia patients by feeding Glo1 knockout mice VB6-deficent diets (KO/VB6(-)). We found that the KO/VB6(-) mice accumulated methylglyoxal (MG) in the brain and showed schizophrenia-like behavioral impairments. Furthermore, we found aberrant gene expression related to mitochondria function in the prefrontal cortex (PFC) of the KO/VB6(-) mice. Finally, we demonstrated abnormal mitochondrial respiratory function and enhanced oxidative stress in the PFC of KO/VB6(-) mice.
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Novel strategy for natural product biosynthesis

Eurekalert - Jul 02 2021 - 00:07
Researchers discover enzyme prototype for formation of ecologically and pharmaceutically important tropone compounds.
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Observation, simulation, and AI join forces to reveal a clear universe

Eurekalert - Jul 02 2021 - 00:07
Japanese astronomers have developed a new artificial intelligence (AI) technique to remove noise in astronomical data due to random variations in galaxy shapes. After extensive training and testing on large mock data created by supercomputer simulations, they then applied this new tool to actual data from Japan's Subaru Telescope and found that the mass distribution derived from using this method is consistent with the currently accepted models of the Universe.
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Uncovering the genetic mechanism behind Rett syndrome

Eurekalert - Jul 02 2021 - 00:07
Kyushu University researchers found that the main gene that causes Rett syndrome, MeCP2, controls the differentiation pattern of neural stem cells through the microRNA miR-199a. Dysfunction in MeCP2 or miR-199a cause neural stem cells to produce more astrocytes than neurons. Furthermore, the researchers found that miR-199a mediates the production of Smad1, a downstream transcription factor of bone morphogenetic protein (BMP) signaling.
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New solution for sleep apnoea

Eurekalert - Jul 02 2021 - 00:07
In an Australian world-first, researchers have successfully repurposed two existing medications to reduce the severity of sleep apnoea in people by at least 30 per cent. Affecting millions around the world, sleep apnoea is a condition where the upper airway from the back of the nose to the throat closes repetitively during sleep, restricting oxygen intake and causing people to wake as often as 100 times or more per hour.
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Guadalupe fur seals continue to recover as new colony discovered

Eurekalert - Jul 02 2021 - 00:07
Guadalupe fur seals (Arctocephalus townsendi) have established a large resting colony in the Gulf of California--bringing the total number of sites where this endangered species now occurs to just four. This new haul-out was discovered on El Farallón de San Ignacio Island, along the mainland coast of Mexico, according to researchers from Mexico and the University of British Columbia.
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Stanford research shows muskrats are a bellwether for a drying delta

Eurekalert - Jul 02 2021 - 00:07
Downstream of hydroelectric dams and Alberta's oil sands, one of the world's largest freshwater deltas is drying out. New Stanford University research suggests long-term drying is making it harder for muskrats to recover from massive die-offs. It's a sign of threats to come for many other species.
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Researchers explore how children learn language

Eurekalert - Jul 02 2021 - 00:07
New research pinpoints how young children quickly learn language, opening new paths to leverage for machine learning
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Bowel cancer data reinforce need to reduce unnecessary antibiotic use

Eurekalert - Jul 02 2021 - 00:07
Doctors and patients are being advised to reduce unnecessary antibiotic use following new data suggesting that these medicines may increase the risk of cancer of the large intestine (colon), especially in people under 50 years.
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Poorer survival in obese colorectal cancer patients possibly linked to lower chemotherapy doses

Eurekalert - Jul 02 2021 - 00:07
Obese patients with colorectal cancer receive lower cumulative doses of adjuvant chemotherapy, relative to their body surface area (BSA), than non-obese patients, show results from a large meta-analysis reported at the ESMO World Congress on Gastrointestinal Cancer 2021.
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Closer to cure: New imaging method tracks cancer treatment efficacy in preclinical studies

Eurekalert - Jul 02 2021 - 00:07
Several cancers grow through immunosuppression, making immunotherapy a promising approach to treating cancers. But several approaches against one highly sought-after target molecule for such treatment have failed in late stage clinical trials. To find out why, scientists will need to study what happens to the target molecule over time once the treatment is administered. Now, in a game-changer for this field, a team from Japan has discovered a new PET-imaging-based method to achieve this tracking.
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Novel technique decodes mechanisms controlling executive functions of the primate brain

Eurekalert - Jul 02 2021 - 00:07
Executive functions allow humans to manage daily activities, which use working memory, and decision-making. However, how these functions are mapped in a primate brain like that of humans, had evaded researchers for a long time. A group of researchers in Japan have now devised a novel chemogenetic method to dissect the neural pathways involved in high-order executive functions. Their findings are published in a new article in Science Advances.
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Oncotarget: Loss of CPAP in oral cancer

Eurekalert - Jul 02 2021 - 00:07
CPAP also plays a vital role in suppressing tumorigenesis in OSCC by facilitating EGFR homeostasis
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