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New research by Joseph Wu (joewu@stanford.edu), Edgar Engelman (edgareng@stanford.edu), and colleagues at Stanford University, US has advanced an old concept to develop a new strategy to train the immune system of mice to recognize cancer cells.

A Sino-Swiss research team has revealed the dramatic increase in flood risk that could occur across Earth's icy Third Pole in response to ongoing climate change. Focusing on the threat from new lakes forming in front of rapidly retreating glaciers, a team (UNIGE) demonstrated that the related flood risk to communities and their infrastructure could almost triple. Important new hotspots of risk will emerge, including within politically sensitive transboundary regions of the Himalaya and Pamir.

Mini-organs or organoids play a big role in the future of medicine. Their countless applications can help develop and implement tailored therapies for each patient. The revolutionary development of organoids started in Utrecht with a group of curious scientists. But when organoid research starting booming, confusion arose. What exactly is an organoid? A group of experts from around the world now publishes the first consensus on what is - and what is not - an organoid.

Scientists in China and Germany have designed an artificial color-changing material that mimics chameleon skin, with luminogens (molecules that make crystals glow) organized into different core and shell hydrogel layers instead of one uniform matrix. The findings, published May 6, 2021 in the journal Cell Reports Physical Science, demonstrate that a two-luminogen hydrogel chemosensor developed with this design can detect seafood freshness by changing color in response to amine vapors released by microbes as fish spoils.

Sea turtles are known for relying on magnetic signatures to find their way across thousands of miles to the very beaches where they hatched. Now, researchers reporting in the journal Current Biology on May 6 have some of the first solid evidence that sharks also rely on magnetic fields for their long-distance forays across the sea.

Seals and sea lions are fast swimming ocean predators that use their flippers to literally fly through the water. But not all seals are the same: some swim with their front flippers while others propel themselves with their back feet.

Young people need additional support and protection in the criminal justice system because they are more susceptible to pleading guilty when innocent, a new study argues.

Developing a new generation of artificial muscles and soft nanorobots for drug delivery are some of the long-term goals of 4D-BIOMAP, an ERC research project being undertaken by the Universidad Carlos III de Madrid (UC3M).This project develops cross-cutting bio-magneto-mechanical methodologies to stimulate and control biological processes such as cell migration and proliferation, the organism's electrophysiological response, and the origin and development of soft tissue pathologies.

A study designed to enroll an equal number of Black and white men with advanced prostate cancer confirms key findings that have been evident in retrospective analyses and suggest potential new avenues for treating Black patients who disproportionately die of the disease.

A program that provides ongoing support to patients with painful conditions and complex medication regimens may also help them avoid using potentially risky opioid pain medications, or reduce the amount they use, a new study finds.

With mass shootings and other seemingly meaningless acts of violence in the headlines all too frequently, strategies to assess the risk and reduce the potential for violent acts are sorely needed. The fourth in a series of five columns devoted to therapeutic risk management of violence - focusing on a method called chain analysis to identify and target pathways leading to violent thoughts and behaviors - appears in the May issue of the Journal of Psychiatric Practice.

MIAMI--A new study led by scientists at the University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science tracked large sharks in Miami and The Bahamas to understand how these migratory animals respond to major storms, like hurricanes.

Humans are exposed to a variety of toxins and chemicals every day. According to the epithelial barrier hypothesis, exposure to many of these substances damages the epithelium, the thin layer of cells that covers the surface of our skin, lungs and intestine. Defective epithelial barriers have been linked to a rise in almost two billion allergic, autoimmune, neurodegenerative and psychiatric diseases.

Calculations predict that atom-thin sheets of carbon chalcogenides will grow wider when stretched in any direction.

Through a unique combination of computer simulations and laboratory experiments, researchers at the Paul Scherrer Institute PSI have discovered new binding sites for active agents - against cancer, for example - on a vital protein of the cell cytoskeleton. Eleven of the sites hadn't been known before. The study is now published in the journal Angewandte Chemie International Edition.

COVID-19 primarily involves the respiratory system, dysfunction in multiple organ systems is common, particularly in the cardiovascular, gastrointestinal, immune, renal, and nervous systems. Patients with transthyretin amyloidosis (ATTR) (a disease caused by an abnormal misfolded protein that causes buildup of amyloid deposits in the heart, peripheral nervous system including the autonomic nervous system, or other organs) represent a population particularly vulnerable to COVID-19 morbidity due to the multisystem nature of ATTR amyloidosis.

Researchers have found an independent association between COVID-19-related income loss and financial strain and depression, according to the latest study from the COVID-19 Resilience Project, run by the Lifespan Brain Institute (LiBI) of Children's Hospital of Philadelphia (CHOP) and Penn Medicine. This association was found in two separate cohorts - one primarily in the United States and one in Israel - and the depressive symptoms worsened over time in participants who were hit financially, above and beyond pandemic-related anxiety.

Researchers have developed an organic-inorganic hybrid crystal which consists of chains in a single direction, yet still forms two-dimensional layers in spite of this. This makes it possible to combine different material components, like pieces in a construction set, to create tailored materials with innovative properties.

A recent study analyses data collect4d at 44 of the darkest places in the world, including the Canary Island Observatories, to develop the first complete reference method to measure the natural brightness of the night sky using low-cost photometers.

Solar-power developers need to explore using lower-quality agricultural land for solar energy, incentivize dual-use (combined agriculture and solar) options, avoid concentrated solar development and engage communities early to achieve New York's green energy goals, according to forthcoming Cornell University research.