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Dana-Farber researchers present key studies at ASCO annual meeting

Eurekalert - May 20 2021 - 00:05
Dana-Farber Cancer Institute researchers are presenting at the 2021 Annual Meeting of the American Society of Clinical Oncology (ASCO). Toni K. Choueiri, MD, will present results from the randomized, double-blind, phase III KEYNOTE-564 trial evaluating pembrolizumab versus placebo after surgery in patients with renal cell carcinoma during ASCO's Plenary Session.
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An inconstant Hubble constant? U-M research suggests fix to cosmological cornerstone

Eurekalert - May 20 2021 - 00:05
More than 90 years ago, astronomer Edwin Hubble observed the first hint of the rate at which the universe expands, called the Hubble constant.
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New research could lead to better treatment for epilepsy

Eurekalert - May 20 2021 - 00:05
Scientists have discovered that the way in which neurons are connected within regions of the brain, can be a better indicator of disease progression and treatment outcomes for people with brain disorders such as epilepsy.
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The driving force behind tropical mudslides

Eurekalert - May 20 2021 - 00:05
Ph.D. candidate Nicolás Pérez-Consuegra notes that geological knowledge is essential for predicting what areas in a tropical mountain range are more prone to have landslides, earthquakes and volcanic eruptions, and the catastrophic consequences that these events might have in the surrounding populations.
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Sheltering people with COVID-19 experiencing homelessness curbs spread

Eurekalert - May 20 2021 - 00:05
A new study provides public health planning authorities with a method of calculating the number of COVID-19 isolation beds they would need for people experiencing homelessness based on level of infection in the city. The research holds promise for controlling spread of the virus - or future infectious diseases - in a population that is highly vulnerable and less likely than many others to access health care services.
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Epigenetic mechanism can explain how chemicals in plastic may cause lower IQ levels

Eurekalert - May 20 2021 - 00:05
The chemical bisphenol F (found in plastics) can induce changes in a gene that is vital for neurological development. This discovery was made by researchers at the universities of Uppsala and Karlstad, Sweden. The mechanism could explain why exposure to this chemical during the fetal stage may be connected with a lower IQ at seven years of age -- an association previously seen by the same research group. The study is published in the scientific journal Environment International.
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Origins of life researchers develop a new ecological biosignature

Eurekalert - May 20 2021 - 00:05
In groundbreaking work, a team led by Santa Fe Institute Professor Chris Kempes has developed a new ecological biosignature that could help scientists detect life in vastly different environments.
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Not all theories can explain the black hole M87*

Eurekalert - May 20 2021 - 00:05
Theoretical physicists at Goethe University Frankfurt have analysed data from the black hole M87* as part of the Event Horizon Telescope (EHT) collaboration to test Albert Einstein's theory of general relativity. According to the tests, the size of the shadow from M87* is in excellent agreement being from a black hole in general relativity, but sets constraints on the properties of black holes in other theories.
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Study finds evidence emotional support animals benefit those with chronic mental illness

Eurekalert - May 20 2021 - 00:05
In a pilot study, researchers at the University of Toledo have brought scientific credence that backs anecdotal reports of emotional support animals having positive impacts on chronic mental health issues.
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Stress from 2016 US presidential election associated with increase in cardiac events

Eurekalert - May 20 2021 - 00:05
A new study in the Journal of the American Heart Association is the first to show that exposure to a stressful political election is strongly associated with an increase in potentially life-threatening cardiac events.
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Solar geoengineering may be effective in alleviating impacts of global warming on crops

Eurekalert - May 20 2021 - 00:05
Solar geoengineering is not a fix-all for climate change but it could be one of several tools to manage climate risks. A growing body of research has explored the ability of solar geoengineering to reduce physical climate changes. But much less is known about how solar geoengineering could affect the ecosystem and, particularly, agriculture. Now, research finds that solar geoengineering may be surprisingly effective in alleviating some of the worst impacts of global warming on crops.
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Immune cells promote proinflammatory fatty liver disease

Eurekalert - May 20 2021 - 00:05
A particular type of dendritic cell is responsible for the tissue damage that occurs in non-alcoholic steatohepatits (NASH) in mice and humans. The dendritic cells cause aggressive, proinflammatory behavior in T cells, as now discovered by researchers from the German Cancer Research Center (DKFZ) in collaboration with colleagues from Israeli research institutes. Blocking these dendritic cells alleviates symptoms in mice. This type of approach might also prevent the development of serious liver damage in NASH patients.
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These cognitive exercises help young children boost their math skills, study shows

Eurekalert - May 20 2021 - 00:05
Young children who practice visual working memory and reasoning tasks improve their math skills more than children who focus on spatial rotation exercises, according to a large study by researchers at Karolinska Institutet in Sweden. The findings support the notion that training spatial cognition can enhance academic performance and that when it comes to math, the type of training matters. The study is published in the journal Nature Human Behaviour.
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Nearly 3% of Americans take immune-weakening drugs that may limit COVID vaccine response

Eurekalert - May 20 2021 - 00:05
A study of more than 3 million insured US adult patients under 65 found that nearly 3% take immunosuppressive drugs that may elevate risk for severe COVID-19 symptoms and hospitalization if they became infected. There is growing evidence that immunosuppressive drugs may also reduce the COVID vaccine's efficacy.
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New AI-based tool can find rare cell populations in large single-cell datasets

Eurekalert - May 20 2021 - 00:05
MD Anderson researchers have developed a first-of-its-kind AI tool to identify rare groups of biologically important cells from the noise of large, complex single-cell datasets. The new tool, called SCMER, can help reserachers gain new insights across many applications.
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Molecule enlists patient's immune system to combat HIV

Eurekalert - May 20 2021 - 00:05
Antiretroviral therapy, the common approach in the treatment of HIV, halts replication of the virus and has saved the lives of millions of people. However, for patients the drug cocktail becomes a lifetime necessity because they continue to harbor latent HIV in a small number of immune system cells. In the absence of treatment, HIV can again replicate and rebound into full blown AIDs.
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Condensing by turning toward the crowd

Eurekalert - May 20 2021 - 00:05
Like water vapor on the bathroom mirror, gas molecules come together and condense into liquid droplets due to the attractive forces between them. In a study published in Nature Physics, researchers have discovered that active particles can condense by turning and moving toward crowded areas.
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New single-cell analysis tool links immune cells to kidney cancer recurrence

Eurekalert - May 20 2021 - 00:05
Newly identified immune cells infiltrate tumors in patients with localized kidney cancer and may be driving the cancer's recurrence, Columbia researchers have found.
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Cardioids -- heartbeat, heartbreak and recovery in a dish

Eurekalert - May 20 2021 - 00:05
Self-organizing heart organoids developed at IMBA -- Institute of Molecular Biotechnology of the Austrian Academy of Sciences -- are also effective injury- and in vitro congenital disease models. These "cardioids" may revolutionize research into cardiovascular disorders and malformations of the heart. The results are published in the journal Cell.
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Solving a natural riddle of water filtration

Eurekalert - May 20 2021 - 00:05
An international, interdisciplinary team of researchers that includes engineers from The University of Austin has found a way to replicate a natural process that moves water between cells, with a goal of improving how we filter out salt and other elements and molecules to create clean water while consuming less energy.
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