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New study: Lack of consideration of sex and gender in COVID-19 clinical studies

Eurekalert - Jul 09 2021 - 00:07
Although COVID-19 affects men and women differently, the large majority of current clinical studies of SARS-CoV-2 and COVID-19 makes no mention of sex/gender. Indeed, only a fraction, 4 percent, explicitly plan to address sex and gender in their analysis, concludes a new analysis of nearly 4,500 studies. 21 percent only take this variable into account when selecting participants while 5.4 % go as far as planning to have sex-matched or representative subgroups and samples.
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New genetic driver of autism and other developmental disorders identified

Eurekalert - Jul 09 2021 - 00:07
An international research group led by Kobe University's Professor TAKUMI Toru has revealed a causal gene (Necdin, NDN) in autism model mice that have the chromosomal abnormality called copy number variation. The researchers hope to illuminate this gene's molecular mechanism in order to contribute towards the creation of new treatment strategies for developmental disorders.
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Recess quality influences student behavior, social-emotional development, OSU study finds

Eurekalert - Jul 09 2021 - 00:07
Recess quality, not just the amount of time spent away from the classroom, plays a major role in whether children experience the full physical, mental and social-emotional benefits of recess, a new study from Oregon State University found.
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Programmable structures from the printer

Eurekalert - Jul 09 2021 - 00:07
Research team develops new method for 3D-printing materials systems that move like a climbing plant.
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Interactive police line-ups improve eyewitness accuracy - study

Eurekalert - Jul 09 2021 - 00:07
Eyewitnesses can identify perpetrators more accurately when they are able to manipulate 3D images of suspects, according to a new study.
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Match matters: The right combination of parents can turn a gene off indefinitely

Eurekalert - Jul 09 2021 - 00:07
A new study by researchers at the University of Maryland provides a potential tool for unraveling the mystery of how experiences can cause inheritable changes to an animal's biology. By mating nematode worms, they produced permanent epigenetic changes that lasted for more than 300 generations. The research was published in the journal Nature Communications.
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MRI can cut overdiagnoses in prostate-cancer screening by half

Eurekalert - Jul 09 2021 - 00:07
Most countries have not introduced nationwide prostate-cancer screening, as current methods result in overdiagnoses and excessive and unnecessary biopsies. A new study by researchers at Karolinska Institutet in Sweden, which is published in The New England Journal of Medicine, indicates that screening by magnetic resonance imaging (MRI) and targeted biopsies could potentially cut overdiagnoses by half. The results are presented today at the European Association of Urology Congress.
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Passing the ball: Shifting responsibility for care coordination from patient to provider

Eurekalert - Jul 09 2021 - 00:07
A new study from U.S. Department of Veterans Affairs, Regenstrief Institute, IUPUI and Icahn School of Medicine at Mount Sinai researchers reports that primary care physicians recognize the need for better coordination and welcome health information exchange (HIE) event notifications as a means of improving the flow of information to enable provision of better patient care.
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Gender pay gap means fewer female candidates on the ballot

Eurekalert - Jul 09 2021 - 00:07
Study analyzing electoral data finds that where gender pay gaps are larger, women candidates obtain fewer votes and are less present on the ballot
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Oncotarget: Urine RNA reveal tumor markers for human bladder cancer

Eurekalert - Jul 09 2021 - 00:07
This Oncotarget work strongly suggests exploiting urine RNAs as diagnostic markers of bladder cancer and it suggests specific novel markers.
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Red Dead Redemption 2 teaches players about wildlife

Eurekalert - Jul 09 2021 - 00:07
Players of the popular game Red Dead Redemption 2 learn how to identify real American wildlife, new research shows.
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To splice or not to splice...

Eurekalert - Jul 08 2021 - 00:07
University of Michigan Center for RNA Biomedicine scientists investigated the efficiency of splicing across different human cell types. The results were surprising in that the splicing process appears to be quite inefficient, leaving most intronic sequences untouched as the transcripts are being synthesized. The study also reports variable patterns between the different introns within a gene and across cell lines, and it further highlights the complexity of how newly transcripts are processed into mature mRNAs.
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Should we delay COVID-19 vaccination in children?

Eurekalert - Jul 08 2021 - 00:07
The net benefit of vaccinating children is unclear, and vulnerable people worldwide should be prioritised instead, say experts in The BMJ today. But others argue that covid-19 vaccines have been approved for some children and that children should not be disadvantaged because of policy choices that impede global vaccination.
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Nearly 8% of men who have sex with men estimated to have syphilis globally

Eurekalert - Jul 08 2021 - 00:07
The global burden of syphilis among men who have sex with men (MSM) has been estimated for the first time in a new study published in The Lancet Global Health.
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The Lancet: CoronaVac COVID-19 vaccine is safe and protects against disease, interim analysis

Eurekalert - Jul 08 2021 - 00:07
Interim data from a phase 3 trial of a COVID-19 vaccine developed in China (CoronaVac) suggests that two doses offer 83.5% protection against symptomatic COVID-19.
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Study shows that antibodies generated by CoronaVac COVID-19 vaccine are less effective against the P.1 Brazil variant

Eurekalert - Jul 08 2021 - 00:07
A new study presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) and published in The Lancet Microbe, shows that antibodies generated by CoronaVac, an inactivated COVID-19 vaccine, work less well against the P.1 Brazil (Gamma) variant.
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Antibody but not T-cell response after first dose of Pfizer COVID-19 vaccine is weakened in patients receiving methotrexate

Eurekalert - Jul 08 2021 - 00:07
A new study presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) and published in The Lancet Rheumatology, shows that the antibody - but not the T-cell - response to the first dose of the Pfizer COVID-19 vaccine is weakened in patients taking the immunosuppressant methotrexate.
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Longest known continuous record of the Paleozoic discovered in Yukon wilderness

Eurekalert - Jul 08 2021 - 00:07
Stanford-led expeditions to a remote area of Yukon, Canada, have uncovered a 120-million-year-long geological record of a time when land plants and complex animals first evolved and ocean oxygen levels began to approach those in the modern world.
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Ecologists compare accuracy of lidar technologies for monitoring forest vegetation

Eurekalert - Jul 08 2021 - 00:07
Andrew Sánchez Meador led a study recently published in Remote Sensing, "Adjudicating Perspectives on Forest Structure: How Do Airborne, Terrestrial, and Mobile Lidar-Derived Estimates Compare?." The study compared vegetation attributes at multiple scales derived from piloted airborne (ALS), fixed-location terrestrial (TLS) and mobile lidar scanning (MLS) to see how these tools might be used to provide detailed information on forest structure and composition.
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Obscuring the truth can promote cooperation

Eurekalert - Jul 08 2021 - 00:07
Obscuring the truth can promote cooperation, according to new research by theoretical biologists from the University of Pennsylvania. Inspired by the example of the file-sharing platform Napster, they show that overstating the level of cooperation in a community can push the community to cooperate more overall.
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