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Multimodal therapy may hold key to treating aggressive childhood cancer

Eurekalert - May 16 2021 - 00:05
Scientists at Children's Cancer Institute found combination of therapies appears to be effective against high-risk neuroblastoma.
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Removal of 'race correction' in pulmonary function tests highlights health disparity

Eurekalert - May 16 2021 - 00:05
By removing "race correction" from the interpretation of pulmonary function test (PFT) results, Black individuals were shown to have a significantly higher prevalence and severity of lung disease, according to research presented at the ATS 2021 International Conference.
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Poverty associated with worse survival, fewer lung transplants in lung disease patients

Eurekalert - May 16 2021 - 00:05
Patients with idiopathic pulmonary fibrosis (IPF), a rare lung disease that causes shortness of breath and low oxygen levels because of lung scarring, have worse outcomes if they live in poor neighborhoods, according to research presented at the ATS 2021 International Conference.
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Novel monoclonal antibody can substantially lower triglycerides in patients with acute pancreatitis

Eurekalert - May 16 2021 - 00:05
The investigational drug evinacumab reduced triglycerides in patients with severe hypertriglyceridemia (sHTG) and a history of hospitalizations for acute pancreatitis in a phase 2 global study led by Mount Sinai.
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Tailored, earlier heart failure rehab has physical, emotional benefits for patients

Eurekalert - May 16 2021 - 00:05
An innovative cardiac rehabilitation intervention started earlier and more custom-tailored to the individual improved physical function, frailty, quality-of-life, and depression in hospitalized heart failure patients, compared to traditional rehab programs.
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Novel rehab program improves outcome for older heart-failure patients, study finds

Eurekalert - May 16 2021 - 00:05
Heart failure (HF) - when the heart can't pump enough blood and oxygen through the body - affects approximately 6.2 million adults in the United States and is the primary cause of hospitalization in the elderly. Unfortunately, older adults with heart failure often have poor outcomes resulting in reduced quality of life, high mortality and frequent rehospitalizations.
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Weighted "lottery" provides greater access to scarce COVID-19 medications

Eurekalert - May 16 2021 - 00:05
A weighted "lottery" designed to increase access to the antiviral drug remdesivir during the May-July 2020 COVID-19 surge for those most affected by the coronavirus, including members of the Black, Latinx and indigenous communities, led to more equitable distribution of the badly needed medication, according to research presented at the ATS 2021 International Conference.
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Baby and regular-strength aspirin work equally well to protect heart health

Eurekalert - May 15 2021 - 00:05
Researchers found no significant differences in cardiovascular events or major bleeding in patients with pre-existing cardiovascular disease who were taking 81 milligrams (mg), also called baby aspirin, versus 325 mg of daily aspirin, according to new data presented at the American College of Cardiology's 70th Annual Scientific Session
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Sacubitril/valsartan does not outperform ACE inhibitor after heart attack

Eurekalert - May 15 2021 - 00:05
The heart failure drug sacubitril/valsartan did not significantly reduce the rate of heart failure or cardiovascular death following a heart attack compared to ramipril, an angiotensin converting enzyme (ACE) inhibitor proven effective in improving survival following heart attacks. Findings from the PARADISE-MI trial were presented at the American College of Cardiology's 70th Annual Scientific Session.
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Left atrial appendage occlusion reduces stroke after heart surgery

Eurekalert - May 15 2021 - 00:05
Patients with an elevated risk of stroke due to heart rhythm problems, or atrial fibrillation (AFib), were much less likely to suffer a stroke after undergoing heart surgery if doctors concurrently performed an additional procedure, called left atrial appendage occlusion (LAAO), according to the results of a trial presented at the American College of Cardiology's 70th Annual Scientific Session.
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Left atrial appendage occlusion associated with low rate of stroke

Eurekalert - May 15 2021 - 00:05
Transcatheter left atrial appendage occlusion (LAAO) with a WATCHMAN device was associated with a low rate of stroke at one year even among older patients with atrial fibrillation (AFib) who faced a high risk for stroke or bleeding based on their previous health history, according to new data presented at the American College of Cardiology's 70th Annual Scientific Session.
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Apixaban not superior to standard care after TAVR

Eurekalert - May 15 2021 - 00:05
The blood thinner apixaban was not superior to standard of care following transcatheter aortic valve replacement (TAVR), according to findings from a new trial called ATLANTIS presented at the American College of Cardiology's 70th Annual Scientific Session.
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Shrinking planets could explain mystery of universe's missing worlds

Eurekalert - May 15 2021 - 00:05
Flatiron Institute researchers have made a breakthrough in accounting for the mysterious lack of exoplanets roughly double Earth's radius -- an enigma called the radius gap. Using data from the Kepler spacecraft, the researchers found that the sizes of the 'missing planets' depends on the ages of the planetary systems. Specifically, the researchers propose that gas-shrouded exoplanets shrink drastically over billions of years, leaping over the radius gap to become relatively smaller rocky super-Earths.
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Early biomarker warning of heart disease for diabetic patients

Eurekalert - May 15 2021 - 00:05
New research has shown that people with type 1 diabetes may have features of premature heart disease induced by the condition often before they even get their diagnosis.
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Low- and high-dose aspirin achieve similar protection, safety for those with heart disease

Eurekalert - May 15 2021 - 00:05
As presented at ACC.21 and published in NEJM, the findings from ADAPTABLE are from the largest aspirin dosing trial conducted in routine care and clinical settings using PCORnet, a national resource advancing more efficient clinical research. The study and trial were funded by the Patient-Centered Outcomes Research Institute and conducted by a research team led by the Duke Clinical Research Institute.
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Simple surgery prevents strokes in heart patients

Eurekalert - May 15 2021 - 00:05
The study tracked 4,811 people in 27 countries who are living with atrial fibrillation and taking blood thinners. Consenting patients undertaking cardiopulmonary bypass surgery were randomly selected for the additional left atrial appendage occlusion surgery; their outcomes compared with those who only took medicine. They were all followed for a median of four years.
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Rutgers reports first instance of COVID-19 triggering recurrent blood clots in arms

Eurekalert - May 15 2021 - 00:05
Researchers at Rutgers Robert Wood Johnson Medical School are reporting the first instance of COVID-19 triggering a rare recurrence of potentially serious blood clots in people's arms.
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Pandemic boosts demand for postal delivery of abortion pill

Eurekalert - May 14 2021 - 00:05
A new study has found that even with clinics nearby, many women choose telehealth visits and the US Postal Service for prescriptions. 
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Terpen-tales: The mystery behind the unique fragrance of the lovely lavender

Eurekalert - May 14 2021 - 00:05
Scientists from China have sequenced and analyzed the genome of lavender to provide insights into what causes its distinct aroma. Their findings shed light into the evolution of this uniquely fragrant plant, which could pave the way for creating improved lavender varieties besides adding to existing knowledge on the evolution, phytochemistry, and ecology of Lamiaceae, the plant family to which lavender belongs.
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Etching process enhances the extraction of hydrogen during water electrolysis

Eurekalert - May 14 2021 - 00:05
Etching the oxide overlayers of metal phosphide electrocatalysts can accelerate the process of surface reconstruction and facilitate the formation of key intermediate phases for catalyzing water electrolysis.
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