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The fluorescence dyes were the dominant species of the near-infrared (NIR) dyes, but the energy gap of the NIR dyes between S1 and S0 is generally small to induce the ultrafast internal conversion dynamics to quench the NIR emission of the fluorescence dyes. Here, scientists based in China proposed a new assumption to construct efficient NIR materials based on the metal-free room-temperature phosphorescence materials, and a series of NIR materials were reported for the demonstration of the assumption.

A minimally invasive procedure that targets the nerves near the kidney has been found to significantly reduce blood pressure in hypertension patients, according to the results of a global multicenter clinical trial led in the UK by researchers at Queen Mary University of London and Barts Health NHS Trust.

How basic physics and chemistry constrain cellular functions in primitive and modern cells.

The study revealed extremely high genetic diversity in the Euphaea yayeyamana in Ishigaki and Iriomote. The genetic diversity within Taiwan's population of Euphaea formosa was significantly lower than that within either Ishigaki or Iriomote islands despite Taiwan being significantly larger with a diverse array of habitats including high mountain ranges that reach 4,000 meters above sea level.

Older people need digital skills training to learn to use digital technology more independently, but they also seek digital training opportunities because of the social benefits they offer, according to a recent study from the University of Eastern Finland.

Decades of research has revealed the remarkable morphological adaptations of sea snakes to aquatic life, which include paddle-shaped tails, salt-excreting glands, and the ability to breathe through their skin. In a new study published in Biological Journal of the Linnean Society, researchers at the University of Adelaide detail the enlarged touch receptors that evolved in male turtle-headed sea snakes (Emydocephalus annulatus), to help them locate and court females in aquatic environments.

A team of astronomers from the National Centre for Radio Astrophysics (NCRA-TIFR), Pune, and the Raman Research Institute, Bangalore, used the Giant Metrewave Radio Telescope to measure the atomic hydrogen gas content of galaxies 9 billion years ago. The new result is a confirmation of the group's earlier result, where they had measured the atomic hydrogen content of galaxies 8 billion years ago, and pushes our understanding of galaxies to even earlier in the universe.

A research team from the University of Copenhagen and University of Helsinki demonstrates it is possible to predict individual preferences based on how a person's brain responses match up to others. This could potentially be used to provide individually tailored media content -- and perhaps even to enlighten us about ourselves.

New research suggests that measuring how patterns of gene expression in white blood cells change in children starting in infancy - before autoantibodies appear indicating an autoimmune reaction against pancreatic β cells - can predict earlier and more robustly which genetically-susceptible individuals will progress to T1D. The international study, based on blood samples longitudinally collected from 400 children in The Environmental Determinants of Diabetes in the Young (TEDDY) consortium, included co-investigators from the University of South Florida Health Informatics Institute.

No one knows what happened in the universe for its first 400,000 years, but a new paper suggests discovering the hypothetical particle axion could shed light on the early history of the universe. What's more, current dark matter experiments may have already detected it in its data.

When we inhale isolated coronavirus particles, more than 65% reach the deepest region of our lungs, new research has discovered, and more of these aerosols reach the right lung than the left.

Monash University researchers have provided a fundamental advance regarding how T cells become activated when encountering pathogens such as viruses.

A preclinical study led by scientists at Sanford Burnham Prebys has established that AAV8-TNAP-D10--a gene therapy that replaces a key enzyme found in bone--may be a safe and effective single-dose treatment for hypophosphatasia (HPP). The study, published in the Journal of Bone and Mineral Research and performed in a murine model of the disease, further supports advancing the therapy toward human clinical trials.

A world-first international study led by the University of South Australia has identified a new drug to stop athletes developing dementia after sustaining repeated head injuries in their career.

Wider clean chemistry applications of the extraordinary Vortex Fluidic Device -- invented by Flinders University's Professor Colin Raston -- are likely in the wake of new research that has been published outlining the seemingly endless possible uses.The defining paper on understanding fluid flow in the Vortex Fluidic Device has just been comprehensively explained in an article published in Nanoscale Advances.

Due to the immunological pathogenesis of IgA nephropathy, patients used to be given immunosuppressive therapy; however, this was shown to have no long-term benefit over optimal supportive therapy. Promising data from the interim analysis of a Phase II study with iptacopan now show that the targeted inhibition of a specific factor of the immune system allows a specific approach to therapy for IgAN without burdening patients with the severe side effects of immunosuppression.

Researchers at Tel Aviv University discovered a process by which a "good" virus selectively destroys the DNA of "bad" bacteria, thereby stopping its reproduction. The discovery may assist in the development of treatments against antibiotic-resistant bacteria that cause infectious diseases.

In hemodialysis patients at high cardiovascular risk, including patients with coronary artery disease and heart failure, lung congestion, a condition predisposing to decompensated heart failure and pulmonary edema, is much common. By means of ultrasound examination of the lungs, the degree of lung congestion can be estimated relatively easily, and the therapy aimed at lung decongestion can be adapted individually.

Many patients with the rare kidney disease FSGS require dialysis in the course of the disease, despite anti-inflammatory corticosteroid therapies. The DAPA-CKD study showed a significant benefit in renal outcomes for chronic kidney disease patients with and without diabetes mellitus, following treatment with dapagliflozin, an SGLT-2 (sodium dependent glucose co-transporter 2) inhibitor [1]. A subgroup analysis of the DAPA-CKD study [2] suggests that the beneficial effect of dapagliflozin extends to patients with FSGS.

That viruses and bacteria can trigger autoimmune processes is well known. In autoimmune disease, the immune system attacks the body's own cells, which can become life-threatening, for example in lupus nephritis. In COVID-19, the same autoantibodies (antiphospholipid (aPL) antibodies) have been found repeatedly in lupus patients - a new study even describes a specific site of attack site where aPL antibodies could trigger a self-reinforcing continuous loop of autoantibody production and cause very severe COVID-19 courses.