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The experimental, lab-made antibody leronlimab can completely prevent nonhuman primates from being infected with the monkey form of HIV, new research published in Nature Communications shows. The results will inform a future human clinical trial evaluating leronlimab as a potential pre-exposure prophylaxis, or PrEP, therapy to prevent human infection from the virus that causes AIDS.

Despite the devastating impact the emerald ashborer beetle has had on forests in the eastern and midwestern parts of the U.S., climate change will have a much larger and widespread impact on these landscapes through the end of the century, according to researchers.

A team of researchers, led by Cornell University professors Chris Barrett and Miguel Gómez, has developed the "Global Food Dollar" method, which distributes the consumer's net purchasing dollar across all farm and post-farmgate activities.

MIT chemical engineers have devised a simpler process for incorporating hydrophobic drugs into tablets or other drug formulations, using nanoemulsions. With this method, it may be possible to make many pills smaller and easier to swallow.

The device was used for the first time to culture two maternal endometrial cell types, revealing the effects of alterations in glucose and insulin levels in the uterine environment.

Research reveals that viruses known as bacteriophages that undergo special evolutionary training increase their capacity to subdue bacteria. The results provide hope in the ongoing battle against antibiotic resistance, a rising threat as deadly bacteria continue to evolve to render many modern drugs ineffective.

A new study examined ERPO use in Oregon in the first 15 months after it was adopted. The study found that while extreme risk protection orders (ERPOs) are commonly considered as a tool to remove guns from dangerous individuals, they should also be considered as a tool to prevent gun purchases by dangerous individuals.

Cowpea mosaic virus, when injected into cancerous tumors, stimulates the immune system to attack and often eliminate the tumor. In a new study, immunology researchers in Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center, in collaboration with researchers at the University of California San Diego Jacobs School of Engineering, characterize the previously unidentified pathways through which CPMV is recognized by the immune system, opening the door for pursuit of CPMV as a new biological cancer treatment.

Artificial intelligence natural language computer applications are becoming increasingly sophisticated, raising the possibility that they could assume a greater role in health care, including interacting with patients. But before these applications enter the clinic, their potential and pitfalls need thoughtful exploration, states a new article in NPJ Digital Medicine.

Youth brain activation data from the largest longitudinal neuroimaging study to date provides valuable new information on the cognitive processes and brain systems that underlie adolescent development and might contribute to mental and physical health challenges in adulthood.

New findings published in JAMA Neurology suggest there is no difference in cognitive outcomes at age 2 among children of healthy women and children of women with epilepsy who took antiseizure medication during pregnancy.

Scientists at the Salk Institute are developing a promising approach for treating type 1 diabetes by using stem cells to create insulin-producing cells (called beta cells) that could replace nonfunctional pancreatic cells.

Customer loyalty programs have been around for decades and are used to help businesses, marketers and sellers build a sustainable relationship with their customers. But do they work? A recent study sought to find out and researchers learned that while yes, customer loyalty programs do work, perhaps not in ways most may assume.

Two new papers explore this question and provide examples of conditions that lead to massive plankton blooms with vastly different potential impacts on the ecosystem, according to McGillicuddy, co-author of both papers. Both papers also point to the importance of using advanced technology--including Video Plankton Recorders, autonomous underwater vehicles, and the Ocean Observatories Initiative's Coastal Pioneer Array--to find and monitor these blooms.

A new study from researchers at Johns Hopkins Bloomberg School of Public Health and colleagues suggests a slowdown in the use of convalescent plasma to treat hospitalized COVID-19 patients led to a higher COVID-19 mortality during a critical period during this past winter's surge.

Microgravity in space perturbs human physiology and is detrimental for astronaut health, a fact first realized during early Apollo missions when astronauts experienced inner ear disturbances, heart arrhythmia, low blood pressure, dehydration, and loss of calcium from their bones after their missions.

RUDN University chemists and their colleagues from Novosibirsk State University, Novosibirsk Institute of Organic Chemistry and The State Research Center of Virology and Biotechnology VECTOR have obtained a new class of compounds that inhibit the replication of the deadly Hantaan virus that affects blood vessels and internal organs of humans. The resulting substances were five times more effective than existing antiviral drugs.

Employees who received automated, personalized feedback on their cafeteria purchases at work made healthier food choices. Although the intervention led to dietary changes, it did not prevent weight gain.

In a subset of patients with partial lipodystrophy and/or NASH, the hormone leptin can be leveraged as a therapeutic agent to move fat out of the liver.

Researchers used protein mapping to show how abnormal levels of the neurotransmitter glutamate impair the functioning of neurons and oligodendrocytes. The findings could serve as a basis for more effective treatment.