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Researchers from University of Tsukuba, in collaboration with scientists in Germany, have created a mouse model of restrictive cardiomyopathy, a disease in which the heart muscle becomes stiff and the heart is unable to properly fill with blood. Their data suggest that the disease results from the accumulation of mutant BAG3 protein, which interferes with the protein quality control system and the machinery for breaking down and recycling damaged proteins, disrupting the heart muscle components.

Electrons are ubiquitous among atoms, subatomic tokens of energy that can independently change how a system behaves -- but they also can change each other. An international research collaboration found that collectively measuring electrons revealed unique and unanticipated findings.

Inhibiting necroptosis, a form of cell death, could yield a new treatment approach for chronic obstructive pulmonary disease (COPD), an inflammatory lung condition also known as emphysema, new research shows. The study, by a team of Australian and Belgian researchers, revealed elevated levels of necroptosis in patients with COPD. By inhibiting necroptosis activity in the lung tissue of COPD patients the researchers found a significant reduction in chronic airway inflammation and lung damage.

Conservationists have long warned of the dangers associated with bears becoming habituated to life in urban areas. Yet, it appears the message hasn't gotten through to everyone.News reports continue to cover seemingly similar situations -- a foraging bear enters a neighbourhood, easily finds high-value food and refuses to leave. The story often ends with conservation officers being forced to euthanize the animal for public safety purposes.

Since 2005, the guidelines for the care of unconscious cardiac arrest patients have been to cool the body temperature down to 33 degrees Celsius. A large, randomised clinical trial led by Lund University and Region Skåne in Sweden has shown that this treatment does not improve survival. The study is published in the New England Journal of Medicine.

African American mothers continue to have the lowest breastfeeding rates, even as the breastfeeding rates have risen in the US over the past 25 years.

New research published in BMJ Open shows that community pharmacy could play a 'key clinical role' in the future of COVID-19 vaccination programmes, according to a study led by Aston University in Birmingham, UK, in collaboration with UK and international researchers.

The role of people infected with malaria without showing symptoms presents a hidden risk to efforts to control the disease after they were found to be responsible for most infections in mosquitoes, according to a study published in The Lancet Infectious Diseases.

A new University of Washington study of requests and donations to the popular crowdfunding site GoFundMe, along with Census data, shows stark inequities in where the money went and how much was donated.

Corticosteroids may be an effective treatment for children who develop a rare but serious condition after COVID-19 infection.

Researchers at the National Eye Institute (NEI) have determined how certain short protein fragments, called peptides, can protect neuronal cells found in the light-sensing retina layer at the back of the eye. The peptides might someday be used to treat degenerative retinal diseases, such as age-related macular degeneration (AMD).

Human-caused wildfire ignitions in Central Oregon are expected to remain steady over the next four decades and lightning-caused ignitions are expected to decline, but the average size of a blaze from either cause is expected to rise, Oregon State University modeling suggests.

An innovative underwater robot known as Mesobot is providing researchers with deeper insight into the vast mid-ocean region known as the "twilight zone." Capable of tracking and recording high-resolution images of slow-moving and fragile zooplankton, gelatinous animals, and particles, Mesobot greatly expands scientists' ability to observe creatures in their mesopelagic habitat with minimal disturbance.

Scientists are already preparing for a possible next coronavirus pandemic to strike, keeping with the seven-year pattern since 2004. In future-looking research, scientists have identified a novel target for a drug to treat SARS-CoV-2 that also could impact a new emerging coronavirus. "God forbid we need this, but we will be ready," said the lead Northwestern scientist.

Researchers have managed to create a stable giant vortex in interacting polariton condensates, addressing a known challenge in quantized fluid dynamics. The findings open possibilities in creating uniquely structured coherent light sources and exploring many-body physics under unique extreme conditions.

Michigan State University entomologists Sarah Smith and Anthony Cognato have discovered more than three dozen species of ambrosia beetles -- beetles that eat ambrosia fungus -- previously unknown to science.

New study results indicate that different comorbid conditions affecting individuals diagnosed with COVID-19 may impact how long they continue to receive positive SARS-CoV-2 polymerase chain reaction (PCR) test results.

In a study of more than 10,600 adult patients hospitalized with COVID-19, women had significantly lower odds than men of in-hospital mortality. They also had fewer admissions to the intensive care unit and less need for mechanical ventilation.

We've seen robots take to the air, dive beneath the waves and perform all sorts of maneuvers on land. Now, researchers at UC Santa Barbara and Georgia Institute of Technology are exploring a new frontier: the ground beneath our feet. Taking their cues from plants and animals that have evolved to navigate subterranean spaces, they've developed a fast, controllable soft robot that can burrow through sand.

An alternate-day intermittent fasting schedule offered less fat-reducing benefits than a matched "traditional" diet that restricts daily energy intake, according to a new, 3-week randomized trial involving 36 participants.