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New mapping technique reveals epigenetic drivers of cancers

Eurekalert - May 10 2021 - 00:05
Scientists have made major advances in understanding and developing treatments for many cancers by identifying genetic mutations that drive the disease. Now a team led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and the New York Genome Center (NYGC) has developed a machine learning technique for detecting other modifications to DNA that have a similar effect.
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Researchers use arcuate organoids to study development and disease of the hypothalamus

Eurekalert - May 10 2021 - 00:05
For the first time, researchers at Penn Medicine created organoids of the arcuate nucleus (ARC),providing an atlas of cell types in the human hypothalamus, which will be a blueprint to further understanding the development of brain disorders, such as certain causes of obesity and autism.
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Early screening tool leads to earlier diagnosis and treatment for autism spectrum disorder

Eurekalert - May 10 2021 - 00:05
Since it debuted in 2011, the Get SET Early program, which provides pediatricians and parents with a relatively simple process to screen for indicators of autism spectrum disorder (ASD) in children as young as age 1, has steadily grown in use and validation. Early screening and identification of ASD has been linked to more effective treatment.
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Invasive species alters marine community, interferes in post-disaster recovery

Eurekalert - May 10 2021 - 00:05
Clavelina oblonga, an invasive marine fouling species, not only reduces diversity in communities it invades, it also interferes in their recovery following natural disasters - a process known as "succession."
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CHEST releases updated guidelines to diagnose and evaluate hypersensitivity pneumonitis

Eurekalert - May 10 2021 - 00:05
The American College of Chest Physicians® (CHEST) recently released new clinical guidelines on the Diagnosis and Evaluation of Hypersensitivity Pneumonitis (HP).
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The formation of the Amazon Basin influenced the distribution of manatees

Eurekalert - May 10 2021 - 00:05
Whole mitochondrial DNA sequencing of the three extant species of the aquatic mammal shows that they first split from their common ancestor after geological events isolated the South American region from the sea. The African species may have originated in migration borne by marine currents.
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Volcanoes on Mars could be active

Eurekalert - May 10 2021 - 00:05
New observations reveal that Mars could still be volcanically active, raising the possibility for habitable conditions in the near surface of Mars in recent history. Ongoing research investigates the possibility that the most recent volcanic activity on Mars, which occurred about 50,000 years ago, might have been triggered by a nearby asteroid impact that happened around the same time.
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Controlling cholesterol in microglia alleviates chronic pain, opioid-free

Eurekalert - May 10 2021 - 00:05
Chemotherapy can induce a painful peripheral neuropathy (CIPN), a chronic condition and common adverse effect for cancer patients undergoing treatment. Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, have used a mouse model to demonstrate the pivotal role of cholesterol in CIPN, and proposed a novel therapeutic approach to reverse it.
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Solving the cocktail party problem

Eurekalert - May 10 2021 - 00:05
Conducting a discussion in a crowded room can be challenging when other conversations and background noise interfere with our ability to focus attention on our conversation partner. Can we absorb information from a few speakers in parallel, or are we limited to understanding speech from only one speaker at a time? Researchers have now moved closer to understanding how the brain deals with the abundance of sounds in our environments, and prioritizes among them.
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Even when they include them, gifted programs aren't serving Black or low-income kids

Eurekalert - May 10 2021 - 00:05
The first nationwide study of outcomes for different gifted subgroups shows the programs may not be adequately serving their Black and low-income students.
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Stanford researchers map how people in cities get a health boost from nature

Eurekalert - May 10 2021 - 00:05
Trees lining a street may encourage people to take a longer stroll or choose to bike to work. New research shows how access to natural areas in cities can improve human health by supporting physical activity. The researchers plan to equip city planners with tools to create healthier, more sustainable cities around the world.
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'Flipping' optical wavefront eliminates distortions in multimode fibers

Eurekalert - May 10 2021 - 00:05
University of Rochester researchers at the Institute of Optics have devised a novel technique, described in a paper in Nature Communications, to "flip" the optical wavefront of an image for both polarizations simultaneously, so that it can be transmitted through a multimode fiber without distortion.
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Does driving wear you out? You might be experiencing 'accelerousal'

Eurekalert - May 10 2021 - 00:05
If you're an anxious driver, accelerousal may be in your genes. Accelerousal is a term for stress provoked by acceleration events, even small ones. New research from the University of Houston takes a look at the phenomenon.
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New theory may revolutionize treatment of endometriosis

Eurekalert - May 10 2021 - 00:05
Endometriosis, a disease found in up to 10 per cent of women, has been enigmatic since it was first described. A new theory developed by researchers at Simon Fraser University suggests a previously overlooked hormone -- testosterone -- has a critical role in its development. The research could have direct impacts on diagnosis and treatment of the disease, signaling hope for women with endometriosis worldwide.
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Grand Challenge research harnesses AI to fight breast cancer

Eurekalert - May 10 2021 - 00:05
BreastPathQ Challenge participants were tasked with developing an automated method for analyzing microscopy images of breast tissue and ranking them according to their tumor cell content, to provide a reliable assessment score. As reported in SPIE's Journal of Medical Imaging (JMI), the challenge produced encouraging results that indicate a path toward integrating artificial intelligence (AI) to streamline clinical assessment of breast cancer.
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Geoscientists find that shallow wastewater injection drives deep earthquakes in Texas

Eurekalert - May 10 2021 - 00:05
In a newly published paper, Virginia Tech geoscientists have found that shallow wastewater injection -- not deep wastewater injections -- can drive widespread deep earthquake activity in unconventional oil and gas production fields.
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Flying at up to Mach 16 could become reality with UCF's developing propulsion system

Eurekalert - May 10 2021 - 00:05
University of Central Florida researchers are building on their technology that could pave the way for hypersonic flight, such as travel from New York to Los Angeles in under 30 minutes. In their latest research published in the journal Proceedings of the National Academy of Sciences, the researchers discovered a way to stabilize the detonation needed for hypersonic propulsion by creating a special hypersonic reaction chamber for jet engines.
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Turns out developing a taste for carbs wasn't a bad thing

Eurekalert - May 10 2021 - 00:05
A new study looking at the evolutionary history of the human oral microbiome shows that Neanderthals and ancient humans adapted to eating starch-rich foods as far back as 100,000 years ago, which is much earlier than previously thought.
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Time running out to save coral reefs

Eurekalert - May 10 2021 - 00:05
New data on the growth rates of coral reefs shows there is still a window of opportunity to save them from eroding by mid-century--but time is running out.
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Single-cell map of early stage lung cancer and normal lung sheds light on tumor development, new therapeutic targets

Eurekalert - May 10 2021 - 00:05
MD Anderson researchers have developed a first-of-its-kind atlas of early-stage lung cancer and surrounding normal lung tissue. The single-cell map provides a valuable resource to learn about tumor development and find new therapeutic targets.
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